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Pitsafe-Plus Tablet is a combination medicine used in the treatment of high cholesterol. It prevents your body from making bad cholesterol and raise the levels of good cholesterol. It also prevents absorption of cholesterol from the intestines.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 21 Sep 2025 | 09:47 PM (IST)
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Pitsafe-Plus Tablet image
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Product introduction

Pitsafe-Plus Tablet can be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. You can help this medicine work better by making a few changes to your lifestyle such as keeping active, stopping smoking, eating a healthy low fat diet and exercise regularly.

Headache, tiredness, muscle pain and back pain are some common side effects of this medicine. These are usually mild but let your doctor know if they bother you or last more than a few days. Let your doctor know if you notice yellowing of skin or eyes, unusually dark urine or dark stools as it might be symptoms of liver damage. You may be asked for regular monitoring of blood sugar level, and liver function while taking this medicine.

Before taking this medicine, let your doctor know if you have any kidney or liver problems or high blood pressure. Pregnant or breastfeeding women should also consult their doctor before taking it.  You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

Uses of Pitsafe-Plus Tablet

Benefits of Pitsafe-Plus Tablet

High cholesterol
Pitsafe-Plus Tablet effectively reduces the high cholesterol levels in your body. Lowering the amount of cholesterol reduces the chances of heart diseases and helps you remain healthier for longer. Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.

Side effects of Pitsafe-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pitsafe-Plus
  • Headache
  • Tiredness
  • Muscle pain
  • Back pain
  • Flatulence
  • Diarrhea
  • Stomach pain
  • Increased liver enzymes

How to use Pitsafe-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pitsafe-Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pitsafe-Plus Tablet works

Pitsafe-Plus Tablet is a combination of two medicines: Pitavastatin and Ezetimibe. Pitavastatin is a lipid-lowering medicine which prevents your body from making "bad" cholesterol (LDL) while raising "good" cholesterol (HDL) levels. Ezetimibe is a cholesterol absorption inhibitor which prevents absorption of cholesterol from the intestines. Together, they provide better reduction of cholesterol in your body.

All substitutes for Pitsafe-Plus Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Pitsafe-Plus Tablet for the treatment of high cholesterol.
  • Take it in addition to regular exercise and low-fat diet to lower levels of fat in the blood.
  • It can be taken with or without food.
  • Notify your doctor if you experience muscle symptoms (pain or weakness), particularly if accompanied with fever.
  • Notify your doctor if you experience stomach pain, loss of hunger, a sick feeling or dark urine.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Pitsafe-Plus Tablet.
Pregnancy

Pregnancy

UNSAFE
Pitsafe-Plus Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Pitsafe-Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

SAFE
Pitsafe-Plus Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Pitsafe-Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pitsafe-Plus Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Pitsafe-Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Pitsafe-Plus Tablet may be needed. Please consult your doctor.
Use of Pitsafe-Plus Tablet is not recommended in patients with moderate to severe liver disease.

Fact Box

Habit Forming

No

Therapeutic Class

CARDIAC
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AAR ESS Remedies Pvt Ltd
Address: Aar Ess Remedies Private Limited, C-28, Sector-65, Noida-201301, Uttar Pradesh, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Pitsafe-Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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