


Pilo 2 Eye Drop
Pilocarpine (2% w/v)
Pilo 2 Eye Drop belongs to a group of medicine called miotics. It is used in the treatment of glaucoma and other eye conditions. It lowers the high pressure inside the eye and helps prevent vision loss and nerve damage.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)
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General Information
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Product introduction
Pilo 2 Eye Drop is for external use only. Use it in the dose and duration as advised by the doctor. If you wear contact lenses, remove them before using the medicine. Do not touch the tip of the dropper to any surface, as it may contaminate the eye drop.
The common side effects are headache, eye irritation, eye pain, blurred vision, and visual impairment. These are usually temporary and only last for a short time. However, if these symptoms persist or worsen, check with your doctor. It is not advised to drive after using this medicine.
Uses of Pilo Eye Drop
Benefits of Pilo Eye Drop
Treatment of Glaucoma
Glaucoma is an eye disease that damages the optic nerve which is essential for proper vision. This damage is often caused by abnormally high pressure in the eye. Pilo 2 Eye Drop is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented. Frequent monitoring, regular checkups can help detect the disease in its early stages.
Glaucoma is an eye disease that damages the optic nerve which is essential for proper vision. This damage is often caused by abnormally high pressure in the eye. Pilo 2 Eye Drop is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented. Frequent monitoring, regular checkups can help detect the disease in its early stages.
Side effects of Pilo Eye Drop
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pilo
- Changes in eye lens
- Headache
- Eye irritation
- Eye pain
- Blurred vision
- Visual impairment
- Eyebrow pain
How to use Pilo Eye Drop
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
How Pilo Eye Drop works
Pilo 2 Eye Drop is a cholinergic agonist. It works by allowing excess aqueous humour (fluid in the eye) to drain from the eye, thereby lowering the increased eye pressure. It also helps reverse the effect of medicines that increase the size of the pupil.
All substitutes for Pilo 2 Eye Drop
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Wash your hands before and after using Pilo 2 Eye Drop to keep your eyes and medicine clean.
- Tilt your head back, pull down your lower eyelid, and apply the exact amount of medicine prescribed.
- Avoid touching the tip of the medicine to your eye or any surface to prevent germs from getting in.
- Your vision may get blurry, or you may have trouble seeing in the dark. Be cautious while driving or moving around.
- Store the medicine in a cool, dry place and do not use it beyond the advised treatment duration, even if some is left or not expired.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- You may experience a stinging sensation for 1-2 mins. Notify your doctor if it persists for longer.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
The safety of Pilo 2 Eye Drop during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Pilo 2 Eye Drop during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Pilo 2 Eye Drop may cause temporary visual disturbances. Do not drive until your vision is clear.
Pilo 2 Eye Drop can cause difficulty in adapting to the dark and blurred vision which may affect your ability to drive.
Pilo 2 Eye Drop can cause difficulty in adapting to the dark and blurred vision which may affect your ability to drive.

Kidney
No interaction found/established

Liver
No interaction found/established
Frequently asked questions
Pilo 2 Eye Drop is used to reduce high pressure inside the eye caused by glaucoma or ocular hypertension. It also helps prepare the eye for laser surgery or eye exams by shrinking the pupil (miosis).
The common side effects of Pilo 2 Eye Drop include headache, blurred vision, eye irritation, dim vision, eye pain, and sometimes nausea. These are usually mild and temporary.
Do not use Pilo 2 Eye Drop if you are allergic to any of its ingredients. Avoid using it if you have conditions where narrow pupils (miosis) can be harmful, such as iritis or uveitis.
Yes, Pilo 2 Eye Drop may cause pupil constriction, which can make it harder to see in dim light or while driving at night. It is advised to exercise caution in low-light situations.
Although rare, serious side effects of Pilo 2 Eye Drop include retinal detachment, especially in people with a history of retinal issues or high myopia. Regular eye exams are important.
Be careful about driving, especially at night, because Pilo 2 Eye Drop makes your pupils smaller, can cause dim vision, and may affect your ability to see in dark conditions. You should wait until you know how the drops affect you before driving or using machinery.
Pilo 2 Eye Drop begins working within 20 minutes after putting Pilo 2 Eye Drop in the eye. The effects typically last for 4 to 6 hours, which is why multiple doses throughout the day are usually needed.
Contact your doctor immediately if you experience severe eye pain, sudden vision changes, signs of eye infection, allergic reactions, severe headache, or nausea or vomiting.
Unlike some other glaucoma medicines, pilocarpine (present in Pilo 2 Eye Drop) usually does not change eye color. However, it can make the pupils smaller, which may temporarily affect the appearance of the eyes while using the medicine.
Fact Box
Chemical Class
Alkaloid derivative
Habit Forming
No
Therapeutic Class
OPHTHAL
Action Class
Cholinomimetic Alkaloids- Pilocarpine
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1120-21.
- PubChem. Pilocarpine. [Accessed 04 Apr. 2019] (online) Available from:
- Pilocarpine. 1974: Alcon Laboratories, INC.; 2009. [Accessed 04 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
- Pilocarpine hydrochloride ophthalmic solution [Prescribing Information]. North Chicago, IL: AbbVie Inc.; 2023. [Accessed 25 Jul. 2024] (online) Available from:
- Pilocarpine Hydrochloride. Somerset Therapeutics, LLC.; 2025. [Acessed 10 Sep. 2025] (online) Available from:
- Pilocarpine hydrochloride ophthalmic solution [Prescribing Information]. Somerset, NJ: Somerset Therapeutics Pvt. Ltd.; 2025. [Accessed 25 Nov. 2025] (online)
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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