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Picon Lotion is a medicine used to treat mild to moderate atopic dermatitis (eczema). It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 17 Jan 2026 | 01:24 AM (IST)
₹711 MRP ₹786.9510% off 
 
 
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General Information

The content is shown in English
Picon Lotion image
Picon Lotion image

Product introduction

Picon Lotion is used for external use only. It should be used 2-4 times a day on the affected area, or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often, and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.


Common side effects of Picon Lotion include application site reactions such as burning, irritation, itching, and redness. If you experience any side effects that persist or get worse, stop the treatment and consult your doctor. Avoid excessive application and do not cover the area with tight dressings, as that can cause irritation.


Picon Lotion should not be used in people who are allergic to pimecrolimus or any of its ingredients, or in those with a weakened immune system. It is not recommended for children under 2 years of age. It should not be applied to infected skin, areas affected by viral infections such as herpes simplex or chickenpox, or to potentially malignant or pre-malignant skin lesions.


Long-term continuous use should be avoided, as the long-term effects on local skin immunity are not fully known, and rare cases of skin cancer and lymphoma have been reported. Excessive sun exposure and UV treatments should also be avoided during treatment. Use of Picon Lotion during pregnancy is not recommended, and caution is advised during breastfeeding.

Uses of Picon Lotion

Benefits of Picon Lotion

Treatment of Atopic dermatitis
Picon Lotion is a non-steroidal anti-inflammatory treatment for mild to moderate atopic dermatitis. It helps reduce redness, itching and rash when topical steroids cannot be used, and can be used intermittently over the long term to help prevent flares, as advised by your doctor.

Side effects of Picon Lotion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Picon
  • Application site reactions (burning, irritation, itching and redness)

How to use Picon Lotion

This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Picon Lotion works

Picon Lotion is an immunomodulating agent that works by blocking the activation of T-cells, a type of immune cell involved in skin inflammation. It specifically inhibits an enzyme called calcineurin, which reduces the release of inflammatory substances like cytokines.

Quick tips

  • Clean the affected area and dry well, and apply a thin layer to the affected areas of skin only. Avoid contact with water (shower, swimming) right after application.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • Inform your doctor if there is no improvement even after two weeks of treatment, or if the skin gets worse.
  • Stop using Picon Lotion and consult your doctor if your eczema becomes infected.
  • Continuous long-term use of the ointment should be avoided. Use as prescribed by your doctor.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Picon Lotion during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Picon Lotion during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

No. Picon Lotion is not a steroid but a non-steroidal immunomodulator. It works differently from steroids and does not cause steroid-related side effects such as skin thinning when used as directed.
Picon Lotion is used to treat mild to moderate atopic dermatitis (eczema) in adults and children aged 2 years and above, especially in cases where topical corticosteroids are not suitable or should be avoided.
Apply a thin layer of Picon Lotion to the affected skin twice daily, or as advised by your doctor. It should be applied only to areas affected by eczema and gently rubbed in. Avoid contact with the eyes, mouth, and mucous membranes.
Yes. Picon Lotion can be used on sensitive areas such as the face, neck, and skin folds, as advised by your doctor. However, it should not be applied to infected skin.
Picon Lotion can be used in children aged 2 years and above. It is not recommended for use in children under 2 years of age.
Picon Lotion should be used for short treatment periods and stopped once symptoms clear. Long-term continuous use is not recommended unless advised by a doctor.
Yes. Excessive exposure to sunlight, sunlamps, or UV therapy should be avoided during treatment. Protective clothing and sun protection measures are advised.
Stop using Picon Lotion and consult your doctor if symptoms worsen, do not improve, or if you develop signs of skin infection, severe irritation, or unusual skin changes.

Fact Box

Chemical Class

Macrolide lactams

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Calcineurin Inhibitors

References

  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
  2. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1053-54.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1121.
  4. Pimecrolimus. Bishop's, Stortford: Meda Pharmaceuticals; 2011 [revised Oct. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
  5. Pimercrolimus. Wehr, Germany: Novartis Pharma Produktions; 2010. [Accessed 06 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
  7. Pimecrolimus [Prescribing Information]. Mississauga, Ontario: Contract Pharmaceutical Limited; 2014. [Accessed 20 Feb. 2024] (online) Available from:
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User feedback

Once A Day
72%
Twice A Day
23%
Twice A Week
2%
Alternate Day
1%
Thrice A Day
1%
Atopic dermatitis
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Eris Lifesciences Ltd
Address: 8th Floor, Commerce House IV, Prahladnagar, Ahmedabad – 380015 Gujarat, India \ 7th Floor, Commerce House-4, Prahlad Nagar, Ahmedabad, Gujarat - 380015

Vendor Details

Country of origin: India
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