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Pimecrolimus is used topically for the treatment of mild or moderate atopic dermatitis (eczema) of the skin in patients aged 2 years and above, especially when topical corticosteroids cannot be used.

How it works

Pimecrolimus belongs to a class of drugs called as immunosupressants. It prevents specific cells of immune system (T cells) from aggravating the symptoms of eczema such as redness and itching.

Common side effects

Edema, Pain, Paresthesia (tingling or pricking sensation), Application site burning, Skin malignancy, Skin peeling, Worsening of eczema, Itching, Irritation


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Expert advice

  • Do not use the pimecrolimus tablet if you are allergic to pimecrolimus or to any other ingredient in the medicine.
  • Do not use pimecrolimus if you have skin conditions other than atopic dermatitis; or affected by a viral infection.
  • Avoid using pimecrolimus if you are pregnant or planning to become pregnant or breast-feeding.
  • Do not use pimecrolimus if you have skin allergies or erythroderma (redness all over the skin) or skin tumors (cancers or swelling of lymph nodes).
  • Avoid exposure to the sun while on pimecrolimus treatment. Use sunscreen and wear protective clothing while going out in the sun.
  • Avoid alcohol intake while using this drug as it may cause flushing.

Frequently asked questions


Q. Is pimecrolimus a steroid?
No. Pimecrolimus is an immuno-suppressant. It is not a steroid.
Q. Is pimecrolimus safe?
Yes. Pimecrolimus is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is pimecrolimus available over the counter?
No. Pimecrolimus is a prescription drug. It is not available over the counter.
Q. What is pimecrolimus cream used for?
Pimecrolimus topical cream is used for treating mild or moderate atopic dermatitis (eczema) of the skin, in cases where corticosteroids cannot be used.

Q. How does it work?
 Pimecrolimus acts by preventing the immune system from worsening the symptoms of eczema, such as itching and redness.

Content on this page was last updated on 19 October, 2016, by Dr. Varun Gupta (MD Pharmacology)