Phosome 50 mg Injection is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills fungi by destroying the fungal cell membrane.

Phosome 50 mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood

It may lead to a few common side effects like headache, nausea and vomiting. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Phosome Injection

Phosome Injection side effects

Common

Headache
Vomiting
Nausea
Stomach cramp
Fever
Anemia (low number of red blood cells)
Heartburn
Rapid breathing

How to use Phosome Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Phosome Injection works

Phosome 50 mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.

Phosome Injection related warnings

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Phosome 50 mg Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Phosome 50 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Lactation

CONSULT YOUR DOCTOR

Phosome 50 mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Phosome 50 mg Injection may cause side effects which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Phosome 50 mg Injection is safe to use in patients with kidney disease. No dose adjustment of Phosome 50 mg Injection is recommended.
However, inform your doctor if you have any underlying kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Phosome 50 mg Injection in patients with liver disease. Please consult your doctor.

What if you miss a dose of Phosome Injection?

If you miss a dose of Phosome 50 mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

Phosome 50 mg Injection

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Expert Advice

It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
Phosome 50 mg Injection can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Interaction with Drugs

Taking Phosome with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Prednisolone

Brand(s): Ranisol

SERIOUS

Deflazacort

Brand(s): Defmark

SERIOUS

Amikacin

Brand(s): Mikasun, Vizocin, Amricin

SERIOUS

Tobramycin

Brand(s): Bactob

SERIOUS

Methylprednisolone

Brand(s): Zencort-M

SERIOUS

Budesonide

Brand(s): Budojet

SERIOUS

Gentamicin

Brand(s): Begenta, Indogenta

SERIOUS

Itraconazole

Brand(s): Itraspan, Canzit, Cositra

SERIOUS

Fluconazole

Brand(s): Fungis

SERIOUS

Ketoconazole

Brand(s): Ketozoe, Ketazol

SERIOUS

View all interactions

Patient Concerns

Questions Related to Phosome

I have some type of fungal infections under and over my private parts.

Dr. Ravi Shankar M.

Ayurveda

Apply Gandhaka Malahar, and Cap Tiktamrit 1-0-1 for one month after food, Aragwadhadhi Kashayam 15 ml twice a day with equal qty of water before food. Dry those parts completely after bath and use Candid dusting powder

Red dot eaching fungal infections last one monthHi doctor good morning

Dr. Deepak Kumar Soni

Skin Specialist

Take Giloy juice daily 10 -15ml with add same quantity of water before breakfast.

Do you have any questions related to Phosome 50 mg Injection?

CONSULT A DOCTOR ONLINE

User Feedback

What were the side-effects while using Phosome 50 mg Injection?

No Side Effec*

60%

Chills

20%

Vomiting

20%

*No Side Effect

How do you take Phosome Injection?

With or witho*

50%

With food

25%

Empty stomach

25%

*With or without food

How much was the improvement?

Excellent59%

Average41%

Please rate Phosome 50 mg Injection on price

Not Expensive16%

Average8%

Expensive76%

What are you using Phosome Injection for?

Severe fungal*

60%

Kala-azar

40%

*Severe fungal infections

FAQs

Q. Is Phosome fungistatic or fungicidal?

Phosome is fungicidal in nature, it acts by killing the fungus

Q. Is Phosome light sensitive?

Phosome is not light sensitive

Q. What is Phosome liposomal?

Liposomal Phosome is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Phosome can substantially improves drug safety especially nephrotoxicity associated with the drug

Q. Is Phosome an antibiotic?

Yes, Phosome is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)

Q. Is Phosome testing dose needed?

Yes, administration of Phosome is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity

Q. How is Phosome administered?

Phosome is either administered as intravenous injection or infusion by a registered medical professional only

Q. How does Phosome cause nephrotoxicity and hyperkalemia?

Phosome can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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References

Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1424.
Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1571-75.
Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 836-38.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 68-69.
Medsacpe. Amphotericin. [Accessed 29 Mar. 2019] (online) Available from:
Amphotericin B. San Dimas, California: Gilead Sciences, Inc.; 2000. [Accessed 04 Feb. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5):4-6. [Accessed 29 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:

Manufacturer/Marketer Address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

A licensed pharmacy from your nearest location will deliver Phosome 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.