


Osra MR Tablet
Mefenamic Acid (500mg)+ Tizanidine (2mg)
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Osra MR Tablet is a medicine used in the treatment of abdominal cramps. It relaxes the muscles in the stomach or intestine and stops sudden muscle contractions, thereby relieving cramps, pain, bloating, and discomfort.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 26 Dec 2025 | 05:16 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 26 Dec 2025 | 05:16 PM (IST)
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General Information
Contains
Mefenamic Acid (500mg)+ Tizanidine (2mg)
Marketer
Bennet Pharmaceuticals Limited
Storage
Store below 30°C
The content is shown in English



Product introduction
Osra MR Tablet should be taken with food. This will prevent you from getting an upset stomach. Take it in the dose and duration as directed by your doctor. Do not take more or use it for longer duration than recommended by the doctor.
The most common side effects of this medicine include nausea, vomiting, diarrhea, indigestion, loss of appetite, sleepiness, weakness, and dryness in mouth. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.
Before taking it, you should let your doctor know if you have any medical conditions or disorders. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you. Pregnant or breastfeeding women should consult their doctor before starting treatment.
The most common side effects of this medicine include nausea, vomiting, diarrhea, indigestion, loss of appetite, sleepiness, weakness, and dryness in mouth. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.
Before taking it, you should let your doctor know if you have any medical conditions or disorders. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you. Pregnant or breastfeeding women should consult their doctor before starting treatment.
Uses of Osra MR Tablet
Benefits of Osra MR Tablet
Abdominal cramp
Osra MR Tablet gives relief from pain and cramps and works best if they are used when the first signs of pain occur. It slows the natural movements of the gut and relaxes the muscles in the stomach and intestines. It also reduces the activity of certain chemicals that causes pain. Inform your doctor if your pain persists or worsens.
Osra MR Tablet gives relief from pain and cramps and works best if they are used when the first signs of pain occur. It slows the natural movements of the gut and relaxes the muscles in the stomach and intestines. It also reduces the activity of certain chemicals that causes pain. Inform your doctor if your pain persists or worsens.
Side effects of Osra MR Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Osra MR
- Nausea
- Vomiting
- Diarrhea
- Indigestion
- Loss of appetite
- Sleepiness
- Weakness
- Dryness in mouth
- Heartburn
How to use Osra MR Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Osra MR Tablet should be taken with or after food.
How Osra MR Tablet works
Osra MR Tablet is a combination of two medicines: Mefenamic acid and Tizanidine which relieve abdominal pain. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Tizanidine is a muscle relaxant which works by acting on the centers in the brain and spinal cord to relieve the muscle stiffness or spasm.
Quick tips
- You have been prescribed Osra MR Tablet to relieve abdominal cramps.
- It is best to take it when the first sign of pain occurs.
- Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
- If you get diarrhea while taking this medicine, consult your doctor immediately.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Do not take indigestion remedies (antacids) within two hours of taking Osra MR Tablet.
- If you develop any new symptoms, or if your symptoms get worse, make an appointment to see your doctor for further advice.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Osra MR Tablet

Pregnancy
CONSULT YOUR DOCTOR
The safety of Osra MR Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CONSULT YOUR DOCTOR
Osra MR Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
UNSAFE
Osra MR Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Osra MR Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Osra MR Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Osra MR Tablet is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.
Use of Osra MR Tablet is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.
Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
References
- FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
- Tizanidine. Ardsley, New York: Acorda Therapeutics Inc.; 1996 [revised 2013]. [Accessed 02 Apr. 20191] (online) Available from:
- ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
- Tizanidine. Hawthorne, New York: Acorda Therapeutics Inc.; 2006]. [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Bennet Pharmaceuticals Limited
Address: 6th Floor, “B” Wing, Manubhai Towers,Sayajigunj, Vadodara - 390005 Gujarat. India
Address: 6th Floor, “B” Wing, Manubhai Towers,Sayajigunj, Vadodara - 390005 Gujarat. India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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