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Orzyme-Plus Tablet is a combination medicine used to treat indigestion and bloating. It relieves symptoms such as heartburn, stomach pain, or irritation. It also neutralizes excessive acid in the stomach and helps in easy passage of gas.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 Feb 2026 | 06:32 PM (IST)
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Orzyme-Plus Tablet image
Orzyme-Plus Tablet image
Orzyme-Plus Tablet image
Orzyme-Plus Tablet image

Product introduction

Orzyme-Plus Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, stomach pain, bloating, constipation, and black colored stools. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. To overcome constipation, you should add fiber-rich foods in your diet and stay hydrated.

Before you start taking this medicine it is important to inform your doctor if you are suffering from liver or kidney disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Lifestyle modifications like having fiber-rich diet, increase fluid intake and regular exercise can help you to get better results.

Uses of Orzyme-Plus Tablet

Benefits of Orzyme-Plus Tablet

Indigestion
Indigestion means discomfort of mainly the upper part of your stomach which may also have other symptoms such as stomach pain, bloating, feeling full etc. Orzyme-Plus Tablet improves the movement of food in your stomach and gut (intestine). This relieves these symptoms and helps in proper digestion of food.
Take Orzyme-Plus Tablet as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Bloating
Bloating refers to excessive buildup of gas in our stomach due to abnormal muscle movement in our stomach and intestines. Orzyme-Plus Tablet improves the movement of food in the stomach and helps prevent bloating.
You should take it exactly as it is prescribed or as it says on the label for it to be effective. Some simple lifestyle changes can help stop or reduce bloating. Eat healthy, avoid spicy or oily food, exercise daily for at least 30 minutes and do not overeat.

Side effects of Orzyme-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Orzyme-Plus
  • Nausea
  • Stomach pain
  • Bloating
  • Constipation
  • Black colored stool

How to use Orzyme-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Orzyme-Plus Tablet should be taken with or after food.

How Orzyme-Plus Tablet works

Orzyme-Plus Tablet is a combination of three medicines: Pancreatin, Simethicone and charcoal. Pancreatin is a digestive enzyme that helps in digestion of food. Simethicone and charcoal are antifoaming medicines which disintegrate gas bubbles and allow easy passage of gas.

Quick tips

  • You have been prescribed Orzyme-Plus Tablet to get relief from indigestion and bloating.
  • Drink plenty of water while taking it.
  • Before taking Orzyme-Plus Tablet inform your doctor if you are allergic to pork or any pig product.
  • Inform your doctor if you experience severe or long-lasting abdominal pain.
  • Do not go to bed immediately after taking a meal. Sit in a relaxed position for some time for better digestion.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Orzyme-Plus Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Orzyme-Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Orzyme-Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Orzyme-Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Orzyme-Plus Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Orzyme-Plus Tablet in patients with liver disease.

Frequently asked questions

Orzyme-Plus Tablet is used to treat indigestion and bloating. It relieves symptoms such as heartburn, stomach pain, or irritation. It also neutralizes excessive acid in the stomach and helps in the easy passage of gas.
Orzyme-Plus Tablet is generally safe, but should not be used if you are allergic to any ingredients. It is not recommended for children under twelve years of age, unless prescribed by a doctor. Always inform your doctor about your allergies and medical history before taking this medicine.
No, you should avoid Orzyme-Plus Tablet if you have intestinal obstruction, recent abdominal surgery, or sudden unexplained stomach pain. These conditions are contraindications, because the medicine could worsen your situation.
Serious side effects of Orzyme-Plus Tablet are rare, but include severe stomach pain, persistent nausea, or black stools that do not improve. If any such symptoms occur, stop the medicine and seek medical attention promptly.
Black stools are common and caused by the activated charcoal present in Orzyme-Plus Tablet. This side effect is harmless, but if the black color is accompanied by pain or bleeding, consult a doctor immediately.
Orzyme-Plus Tablet should not be used if you have active pancreatitis or worsening chronic pancreatic diseases without a doctor's supervision, because it may aggravate your condition.
Mild constipation or diarrhea may occur after taking Orzyme-Plus Tablet, but usually resolves on its own. Drink plenty of water to help manage constipation, and contact your doctor if diarrhea is severe or persistent.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biocyte Organics Pvt Ltd
Address: House No. 112, Meerpur Cantt, Kanpur - 208004, Uttar Pradesh

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Orzyme-Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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