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Opel Plus Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 16 Mar 2026 | 02:55 AM (IST)
Opel Plus Tablet is a combination medicine that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.
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Opel Plus Tablet is currently sold out
Same composition alternative:
Nicip Plus 100mg/500mg Tablet
₹69₹75
Available alternative from Cipla
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Opel Plus Tablet
Opel Plus Tablet
strip of 10 tablets
₹23.6
₹25.78
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Same composition
Nicip Plus 100mg/500mg Tablet
Nicip Plus 100mg/500mg Tablet
strip of 10 tablets
Nimesulide (100mg) + Paracetamol (500mg)
by Cipla Ltd
Get by Tomorrow
₹69
₹5.86 per tablet

₹58.6

order for
₹1200

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General Information

Contains

Nimesulide (100mg)+ Paracetamol (500mg)

Marketer

Stanford Biotech Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Opel Plus Tablet image
Opel Plus Tablet image

Product introduction

Opel Plus Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, and increased liver enzymes. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.


Before taking it, you should let your doctor know if you have a history of ulcers or bleeding in your stomach, high blood pressure, or any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.


Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.


Note: As per the Ministry of Health and Family Welfare, Opel Plus Tablet is banned for children under 12 years of age.

Uses of Opel Plus Tablet

Benefits of Opel Plus Tablet

Pain relief
Opel Plus Tablet is a combination of two medicines that belong to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Side effects of Opel Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Opel Plus
  • Nausea
  • Vomiting
  • Diarrhea
  • Increased liver enzymes

How to use Opel Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Opel Plus Tablet should be taken with or after food.

How Opel Plus Tablet works

Opel Plus Tablet is a combination of two medicines: Nimesulide and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).

All substitutes for Opel Plus Tablet

For information purposes only. Consult a doctor before taking any medicine.

Nicip Plus 100mg/500mg Tablet

by Cipla Ltd
₹6.9/tablet
192% costlier
<h3 class=bodySemiBold>Nicip Plus 100mg/500mg Tablet</h3>

Dolide Cold 100 mg/500 mg Tablet

by Embiotic Laboratories Pvt Ltd
₹5.6/tablet
137% costlier
<h3 class=bodySemiBold>Dolide Cold 100 mg/500 mg Tablet</h3>

Nimol Plus Tablet

by Ben Pharmaceuticals
₹5.1/tablet
116% costlier
<h3 class=bodySemiBold>Nimol Plus Tablet</h3>

Algiril 100 mg/500 mg Tablet

by P & B Pharmaceuticals Ltd
₹4.63/tablet
96% costlier
<h3 class=bodySemiBold>Algiril 100 mg/500 mg Tablet</h3>

Nimisun Plus Tablet

by Baksun Healthcare Pvt Ltd
₹4.28/tablet
81% costlier
<h3 class=bodySemiBold>Nimisun Plus Tablet</h3>

Quick tips

  • You have been prescribed this combination medicine for relieving pain and inflammation.
  • Take it with food to avoid getting an upset stomach.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Opel Plus Tablet.
Pregnancy

Pregnancy

UNSAFE
Opel Plus Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Opel Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Opel Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Opel Plus Tablet in patients with kidney disease. Please consult your doctor.
Use of Opel Plus Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Opel Plus Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Opel Plus Tablet is a combination of two medicines: Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Opel Plus Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if your physician has advised you to do so.
Yes, the use of Opel Plus Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice any signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
The use of Opel Plus Tablet is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should also be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.
Yes, Opel Plus Tablet can be taken with Vitamin B-complex preparations. While Opel Plus Tablet helps to relieve pain, Vitamin B-complex helps to correct the vitamin deficiency that might be causing your symptoms.
No, Opel Plus Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Opel Plus Tablet contains Nimesulide and Paracetamol and both these medicines are known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.
No, you should avoid taking a higher than the recommended dose of Opel Plus Tablet as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
  2. ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
  4. ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
  5. Nimesulide and paracetamol. Panchkula, Haryana: Biofield Pharma Pvt. Ltd.; [Accessed 12 Feb. 2026] (online). Available from:
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Pain relief
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Average
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Stanford Biotech Pvt Ltd
Address: 8 , Industrial Area Mahatpur,(H.P) -174315

Vendor Details

Country of origin: India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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