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Olpress-CT 40 Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 17 Feb 2026 | 06:28 PM (IST)
Olpress-CT 40 Tablet is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.
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Omnipres CH 40mg/12.5mg Tablet
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Olpress-CT 40 Tablet
Olpress-CT 40 Tablet
strip of 15 tablets
₹193
₹213.75
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Omnipres CH 40mg/12.5mg Tablet
Omnipres CH 40mg/12.5mg Tablet
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Olpress-CT 40 Tablet image
Olpress-CT 40 Tablet image

Product introduction

You can take Olpress-CT 40 Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.


The most common side effect is dizziness. Other side effects include feeling a headache, nausea, indigestion, and stomachache. Frequent urination is not a side effect of this medicine. It is the purpose of chlorthalidone and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.


This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.

Uses of Olpress-CT Tablet

Benefits of Olpress-CT Tablet

Hypertension (high blood pressure)
Olpress-CT 40 Tablet is a combination of two medicines namely Olmesartan and chlorthalidone. It is generally used when one medicine alone is not controlling your blood pressure effectively. Olmesartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Chlorthalidone is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Side effects of Olpress-CT Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Olpress-CT
  • Nausea
  • Headache
  • Dizziness
  • Indigestion
  • Diarrhea
  • Stomach pain
  • Gastroenteritis
  • Tiredness
  • Sore throat
  • Runny nose
  • Bronchitis (inflammation of the airways)
  • Flu-like symptoms
  • Cough
  • Joint pain
  • Urinary tract infection
  • Blood in urine

How to use Olpress-CT Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olpress-CT 40 Tablet may be taken with or without food.

How Olpress-CT Tablet works

Olpress-CT 40 Tablet is a combination of olmesartan medoxomil and chlorthalidone. Olmesartan medoxomil works by blocking the action of angiotensin II, a substance that causes blood vessels to narrow, thereby relaxing and widening the blood vessels to lower blood pressure. Chlorthalidone is a diuretic that helps remove excess salt and water from the body through urine, reducing fluid volume and easing the workload on the heart. Together, they help lower and control blood pressure effectively.

Quick tips

  • You have been prescribed Olpress-CT 40 Tablet for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Olpress-CT 40 Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position. 
  • Use of Olpress-CT 40 Tablet during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Olpress-CT 40 Tablet.
Pregnancy

Pregnancy

UNSAFE
Olpress-CT 40 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Olpress-CT 40 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Olpress-CT 40 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Olpress-CT 40 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Olpress-CT 40 Tablet is not recommended in these patients.
Liver

Liver

UNSAFE
Olpress-CT 40 Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Olpress-CT 40 Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

You may notice a decrease in your blood pressure effectively within 2 weeks of starting Olpress-CT 40 Tablet. However, it may take about 8 weeks to see the full benefits of this medicine. Talk to your doctor in case you have any concerns regarding Olpress-CT 40 Tablet, but do not stop taking it without consulting the doctor.
Your doctor may suggest to take your first dose before bedtime, considering that this medicine can make you feel dizzy. After the very first dose you can take Olpress-CT 40 Tablet at any time of the day. It is important to take this medicine at the same time every day. If not sure, contact your doctor.
Yes, the use of Olpress-CT 40 Tablet can make you feel dizzy. This may occur when you suddenly get up from a lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Lifestyle changes play a major role in keeping you healthy if you are taking Olpress-CT 40 Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Olpress-CT 40 Tablet and to keep yourself healthy.
No, Olpress-CT 40 Tablet does not cause weight gain. However, in very rare cases, chronic diarrhea with substantial weight loss may occur. If a patient develops diarrhea while taking Olpress-CT 40 Tablet and no other cause of diarrhea can be deduced, the doctor may suggest discontinuation of the medicine and recommend another medicine.
The serious side effects of Olpress-CT 40 Tablet include skin rash or itchiness, painful joints, fast heart beat, shortness of breath or tightness in the chest. Serious side effects may also include aching, tender or weak muscles not caused by exercise and swelling of the hands, feet or ankles. Olpress-CT 40 Tablet may also cause symptoms that may indicate high potassium levels in the blood, such as nausea, diarrhea, muscle weakness and change in heart rhythm. If you experience any of these symptoms, call your doctor immediately.
Some blood pressure medicines (including water pills like hydrochlorothiazide) may affect a man’s ability to gain or maintain an erection (erectile dysfunction). However, it is thought that other blood pressure medicines can actually improve erectile dysfunction. If you are worried or notice some changes, talk to your doctor. There is no firm evidence which suggests any effect on the fertility of either men or women with the use of Olpress-CT 40 Tablet.
You may have to take Olpress-CT 40 Tablet life long. Olpress-CT 40 Tablet controls high blood pressure but does not cure it. Do not stop taking it even if your blood pressure is well controlled. Olpress-CT 40 Tablet is generally considered safe to be taken for a long term. In some cases, long-term use may adversely affect the kidneys and the kidneys may not function as they should. Therefore, your doctor may prescribe regular blood tests to check urea, creatinine and potassium levels to keep a track of your kidneys functions.
Your doctor may advise you to stop taking Olpress-CT 40 Tablet 24 hours before surgery. This is because Olpress-CT 40 Tablet can further reduce your blood pressure when used with anesthetics. So, inform your doctor that you are taking Olpress-CT 40 Tablet if you will be given general anesthetics (medicines that put you to sleep) or are scheduled to have any surgery.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Arche Medichem Pvt Ltd
Address: 2210-A SF, TURKMAN GATE NEW DELHI North East DL 110006 IN

Vendor Details

Country of origin: India
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