Olmesafe AM Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 06 Feb 2026 | 05:04 PM (IST)

Olmesafe AM Tablet contains two medicines, both of which help to control high blood pressure. Lowering blood pressure helps to reduce your risk of having a heart attack or a stroke in the future.

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₹94 MRP ₹104.0610% off

Olmesafe AM Tablet is currently sold out

Same composition alternative:

Olmo AM 20mg/5mg Tablet

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Olmesafe AM Tablet

strip of 10 tablets

₹94

~~₹104.06~~

Same composition

Olmo AM 20mg/5mg Tablet

strip of 10 tablets

Olmesartan Medoxomil (20mg) + Amlodipine (5mg)

by Knoll Pharmaceuticals Ltd

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General Information

Contains

Olmesartan Medoxomil (20mg)+ Amlodipine (5mg)

Marketer

Aristo Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Olmesafe AM Tablet may be taken on an empty stomach or along with food. However, it is better to take it regularly at a fixed time each day, as prescribed by your doctor. The dose will depend on your condition and how you respond to the medicine. It is important to keep taking this medicine even if you feel well. By lowering your blood pressure, it is reducing your risk of heart attack or stroke so do not stop taking it unless your doctor tells you to. You can help this medication work better by making a few changes to your lifestyle by being active, stopping smoking and eating low salt and low-fat diet.

The most common side effects of this medicine include swelling in your ankles or feet (edema), sleepiness, dizziness, headache, taste change, upset stomach, and tiredness. Since it may cause sleepiness and dizziness, do not drive or do anything requiring concentration until you know how it affects you. Talk to your doctor if any of the side effects bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems or severe dehydration. Pregnant or breastfeeding women should also consult their doctor before taking it. While using this medicine, your blood pressure will be monitored regularly and your kidney function may also need to be tested.

Uses of Olmesafe AM Tablet

Hypertension (high blood pressure)

Benefits of Olmesafe AM Tablet

Hypertension (high blood pressure)
Both of the medicines in this combination work to lower blood pressure but in different ways. Together they help to relax blood vessels and make it easier for your heart to pump blood around your body. This lowers blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Side effects of Olmesafe AM Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Olmesafe AM

Sleepiness
Taste change
Ankle swelling
Headache
Flushing (sense of warmth in the face, ears, neck and trunk)
Dizziness
Tiredness
Palpitations
Upset stomach
Peripheral edema
Increased triglyceride level in blood
Increased uric acid level in blood
Bronchitis (inflammation of the airways)
Muscle cramp
Urinary tract infection
Increased liver enzymes

How to use Olmesafe AM Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olmesafe AM Tablet may be taken with or without food.

How Olmesafe AM Tablet works

Olmesafe AM Tablet is a combination of two medicines: Olmesartan Medoxomil and Amlodipine which lower blood pressure effectively. Olmesartan Medoxomil is an angiotensin receptor blocker (ARB) and Amlodipine is a calcium channel blocker (CCB). They work by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body.

All substitutes for Olmesafe AM Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Olmesafe AM Tablet is a combination of two medicines that provides better blood pressure control than either medicine alone.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
It may cause you to feel lightheaded or weak especially when you stand up. Rise slowly if you have been sitting or lying down.
Avoid consuming alcohol as it may enhance the blood pressure lowering effect of Olmesafe AM Tablet.
It can cause ankle or foot swelling. Raise your legs while you are sitting down and talk to your doctor if it does not go away.
Do not take Olmesafe AM Tablet Tablet if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Olmesafe AM Tablet.

Pregnancy

UNSAFE

Olmesafe AM Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Olmesafe AM Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Olmesafe AM Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Olmesafe AM Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Olmesafe AM Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Olmesafe AM Tablet is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.

Frequently asked questions

How long does it take for Olmesafe AM Tablet to work?

You may notice a decrease in your blood pressure effectively within 2 weeks of starting Olmesafe AM Tablet. However, it may take about 8 weeks to see the full benefits of this medicine. Talk to your doctor in case you have any concerns regarding Olmesafe AM Tablet, but do not stop taking it without consulting the doctor.

At what time of the day should you take Olmesafe AM Tablet?

Your doctor may suggest to take your first dose before bedtime, considering that this medicine can make you feel dizzy. After the very first dose you can take Olmesafe AM Tablet at any time of the day. It is important to take this medicine at the same time every day.

Can I feel dizzy after taking Olmesafe AM Tablet?

Yes, the use of Olmesafe AM Tablet can make you feel dizzy. This may occur when you suddenly get up from a lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

What are the other lifestyle changes I should make while using Olmesafe AM Tablet?

Lifestyle changes play a major role in keeping you healthy if you are taking Olmesafe AM Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Olmesafe AM Tablet and to keep yourself healthy.

Can Olmesafe AM Tablet cause weight gain?

No, Olmesafe AM Tablet does not cause weight gain. However, in very rare cases, chronic diarrhea with substantial weight loss may occur. If a patient develops diarrhea while taking Olmesafe AM Tablet and no other cause of diarrhea can be deduced, the doctor may suggest discontinuation of the medicine and recommend another medicine.

What are the serious side effects of Olmesafe AM Tablet?

The serious side effects of Olmesafe AM Tablet include skin rash or itchiness, painful joints, fast heart beat, shortness of breath or tightness in the chest. Serious side effects may also include aching, tender or weak muscles (not caused by exercise), and swelling of the hands, feet or ankles. Olmesafe AM Tablet may also cause symptoms that may indicate high potassium levels in the blood, such as nausea, diarrhea, muscle weakness and change in heart rhythm. If you experience any of these symptoms, call your doctor immediately.

Can Olmesafe AM Tablet affect my fertility or sex life?

Some blood pressure medicines (including water pills like hydrochlorothiazide) may affect a man’s ability to gain or maintain an erection (erectile dysfunction). However, it is thought that other blood pressure medicines can actually improve erectile dysfunction. If you are worried or notice some changes, talk to your doctor. There is no firm evidence which suggests any effect on the fertility of either men or women with the use of Olmesafe AM Tablet.

For how long do I need to take Olmesafe AM Tablet? Is it safe to take long term?

You may have to take Olmesafe AM Tablet life long. Olmesafe AM Tablet controls high blood pressure but does not cure it. Do not stop taking it even if your blood pressure is well controlled. Olmesafe AM Tablet is generally considered safe to be taken for a long term. In some cases, long-term use may adversely affect the kidneys and the kidneys may not function as they should. Therefore, your doctor may prescribe regular blood tests to check urea, creatinine and potassium levels to keep a track of how well your kidneys are working.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Related lab tests

Kidney Function Test

References

User feedback

Patients taking Olmesafe AM Tablet

Once A Day

89%

Twice A Day

Alternate Day

What are you using Olmesafe AM Tablet for?

Hypertension (high blood pressure)

100%

How much was the improvement?

Average

100%

What were the side-effects while using Olmesafe AM Tablet?

Sleepiness

67%

Weakness

33%

How do you take Olmesafe AM Tablet?

With food

100%

Please rate Olmesafe AM Tablet on price

Average

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India. / Regd, Office: 23 -A Shah Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai-400053 Maharashtra, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Olmesafe AM Tablet

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Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Olmesafe AM Tablet

Benefits of Olmesafe AM Tablet

Side effects of Olmesafe AM Tablet

How to use Olmesafe AM Tablet

How Olmesafe AM Tablet works

All substitutes for Olmesafe AM Tablet

Olmo AM 20mg/5mg Tablet

Olmezest AM Tablet

OLsar-A 20 Tablet

Olmetrack AM Tablet

Olmy-A Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

How long does it take for Olmesafe AM Tablet to work?

At what time of the day should you take Olmesafe AM Tablet?

Can I feel dizzy after taking Olmesafe AM Tablet?

What are the other lifestyle changes I should make while using Olmesafe AM Tablet?

Can Olmesafe AM Tablet cause weight gain?

What are the serious side effects of Olmesafe AM Tablet?

Can Olmesafe AM Tablet affect my fertility or sex life?

For how long do I need to take Olmesafe AM Tablet? Is it safe to take long term?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Kidney Function Test

References

User feedback

Patients taking Olmesafe AM Tablet

What are you using Olmesafe AM Tablet for?

How much was the improvement?

What were the side-effects while using Olmesafe AM Tablet?

How do you take Olmesafe AM Tablet?

Please rate Olmesafe AM Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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