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Oflo Plus Cream

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 31 Jan 2026 | 02:03 AM (IST)
Oflo Plus Cream is a combination of medicine that is used to treat various types of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching. It also has antimicrobial action against infection-causing microorganisms.
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Oflo Plus Cream
Oflo Plus Cream
tube of 15 gm Cream
₹76.3
₹83.44
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Itrostred OC Cream
tube of 15 gm Cream
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The content is shown in English
Oflo Plus Cream image
Oflo Plus Cream image

Product introduction

Oflo Plus Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor. 

This medicine is generally safe to use. However, you might experience application site irritation, redness and burning sensation at the application site. If these side effects persist for a longer duration, inform your doctor. Regular application of moisturizer to the skin can help to overcome or prevent dryness of the skin. 

It is not likely that other medicines you take by mouth or injection will affect the way it works, but talk to your doctor before using it if you have used a similar medicine before and had an allergic reaction. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Oflo Plus Cream

Benefits of Oflo Plus Cream

Skin infections
Oflo Plus Cream is used to treat skin infections caused by microorganisms such as bacteria and fungi. It works by killing and stopping the growth of infection causing microorganisms, thereby clearing the infection and relieving the symptoms. It also blocks the release of chemicals that cause symptoms such as itching, redness and swelling. Therefore this medicine relieves the inflammation due to these infections.

You should use this medicine for as long as it is prescribed, even if your symptoms disappear, otherwise they may come back. Depending on the type of infection you are treating, this may be several weeks. Even after your infection is completely cured, you may have to apply it occasionally to prevent the symptoms from returning.

Side effects of Oflo Plus Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oflo Plus
  • Limited data available

How to use Oflo Plus Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Oflo Plus Cream works

Oflo Plus Cream is a combination of four medicines: Ofloxacin, Ornidazole, Itraconazole and Clobetasol. Ofloxacin is an antibiotic that kills bacteria by preventing them from reproducing and repairing themselves. Ornidazole is also an antibiotic that kills other infectious microorganisms in addition to bacteria by damaging the DNA. Itraconazole is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection. Clobetasol is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.

Quick tips

  • You have been prescribed Oflo Plus Cream to get relief from itching, swelling, and other discomforts due to skin infections.
  • Apply it as a thin layer onto a clean, dry, unbroken infected area of skin.
  • Don't use this medicine more often or for longer than advised by your doctor. Inform your doctor if the treated skin area does not show any improvement after 1 week of treatment.
  • Do not share your towel or clothes with anyone and wear clean clothes every day to prevent infection.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Oflo Plus Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Oflo Plus Cream may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Oflo Plus Cream is prescribed for complex or mixed skin infections where bacteria, fungi, and parasites may all be involved, along with severe inflammation.
Yes, Oflo Plus Cream is often prescribed when ringworm (tinea) gets severely inflamed or develops a secondary bacterial infection, helping calm the area while clearing multiple types of germs.
Yes, moist skin folds are prone to mixed infections. Your doctor may advise applying a thin layer of Oflo Plus Cream on clean, dry skin.
Many people notice less itching and redness within a few days of using Oflo Plus Cream, with clearer improvement in infection signs over 1 to 2 weeks of consistent topical use.
If your skin gets worse or shows new symptoms during Oflo Plus Cream treatment, stop the medicine and contact your doctor immediately. Worsening redness, spreading rash, or new blisters may indicate resistance, allergy, or a different underlying condition.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA
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100% genuine products
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aman Healthcare
Address: 3rd Floor, Office No..05, Raipur kalan, 160102, Chandigarh, India

Vendor Details

Country of origin: India
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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