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Nucef SB Injection

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Nucef SB Injection is a combination medicine. It is prescribed to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.
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Nucef SB Injection is currently sold out
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Ceptidar S 1.5G Injection
₹324₹367.97
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Nucef SB Injection
Nucef SB Injection
vial of 1 Injection
₹150
₹164.48
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Same composition
Ceptidar S 1.5G Injection
Ceptidar S 1.5G Injection
vial of 1 ml Injection
by Lupin Ltd
Get by Thu, 9 Apr
₹324
₹275.0 per unit

₹275

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₹1200

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Nucef SB Injection image
Nucef SB Injection image

Product introduction

Nucef SB Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Nucef SB Injection

Benefits of Nucef SB Injection

Treatment of Bacterial infections
Nucef SB Injection contains two different medicines, Cefoperazone and Sulbactum, that work together to kill the bacteria that cause infections. Cefoperazone works by stopping the growth of bacteria. Sulbactam reduces resistance and enhances the activity of Cefoperazone against bacteria.

Nucef SB Injection can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Nucef SB Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nucef SB
  • Decreased white blood cell count (neutrophils)
  • Decreased white blood cell count (lymphocytes)
  • Decreased hemoglobin
  • Decreased hematocrit level
  • Low blood platelets
  • Coagulation disorder
  • Increased white blood cell count (eosinophils)
  • Diarrhea
  • Nausea
  • Increased alanine aminotransferase
  • Increased aspartate aminotransferase
  • Increased alkaline phosphatase level in blood
  • Vomiting
  • Increased bilirubin in the blood

How to use Nucef SB Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nucef SB Injection works

Nucef SB Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

Quick tips

  • You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance. 
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Nucef SB Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Stop taking Nucef SB Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Safety advice

Alcohol

Alcohol

UNSAFE
Consumption of alcohol with Nucef SB Injection may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Nucef SB Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Nucef SB Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Nucef SB Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Nucef SB Injection in patients with liver disease.

Frequently asked questions

Nucef SB Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.
Usually, Nucef SB Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Fact Box

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Therapeutic Class

ANTI INFECTIVES
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Neuron Pharmaceuticals
Address: OFFICE NO.404/B,4th FLOOR HAASH COMPLEX LAW GARDEN ROAD ELLIS BRIDGE AHMEDABAD-380006

Vendor Details

Country of origin: India
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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