Cefoperazone + Sulbactam

Written By Dr. Syeda Aafia

Reviewed By Dr. Rajeev Sharma

Last updated 25 Nov 2025 | 09:37 AM (UTC)

Cefoperazone + Sulbactam Uses

Cefoperazone+Sulbactam is used in the treatment of bacterial infections.

Available generics for Cefoperazone + Sulbactam

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Cekozef-S 250mg/125mg Injection

vial of 1 injection

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₹75.9

~~₹84~~

10% off

Minimum order quantity: 1

Saltumax 1000 mg/1000 mg Injection

vial of 5 ml injection

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₹237

~~₹262.5~~

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Minimum order quantity: 1

How Cefoperazone + Sulbactam works

Cefoperazone + Sulbactam is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

Common side effects of Cefoperazone + Sulbactam

Decreased white blood cell count (neutrophils), Decreased white blood cell count (lymphocytes), Decreased hemoglobin, Decreased hematocrit level, Low blood platelets, Coagulation disorder, Increased white blood cell count (eosinophils), Diarrhea, Nausea, Increased alanine aminotransferase, Increased aspartate aminotransferase, Increased alkaline phosphatase level in blood, Vomiting, Increased bilirubin in the blood

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Medicine brands for Cefoperazone + Sulbactam

Ipca Laboratories Ltd

Macleods Pharmaceuticals Pvt Ltd

₹171 to ₹275

2 variant(s)

3Cef Novo

Alkem Laboratories Ltd

₹81 to ₹279

3 variant(s)

Fytobact

Cadila Pharmaceuticals Ltd

₹153 to ₹362

4 variant(s)

Troyperazone S

Troikaa Pharmaceuticals Ltd.

₹372 to ₹489

2 variant(s)

Kephazon S Forte

United Biotech Pvt Ltd

Aristo Pharmaceuticals Pvt Ltd

₹240 to ₹240

1 variant(s)

Expert advice for Cefoperazone + Sulbactam

You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Cefoperazone + Sulbactam may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Cefoperazone + Sulbactam and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Frequently asked questions for Cefoperazone + Sulbactam

Q. What is Cefoperazone+Sulbactam?

Cefoperazone+Sulbactam is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

Q. How long does Cefoperazone+Sulbactam takes to work?

Usually, Cefoperazone+Sulbactam starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Q. What if I don't get better after using Cefoperazone+Sulbactam?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.