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NSD Plus Suspension

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 21 Sep 2025 | 05:40 PM (IST)
NSD Plus Suspension is a mixture of two medicines. They belong to a class of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDS). Such medicines, including NSD Plus Suspension, help lower body temperature (fever) and reduce pain and inflammation (redness and swelling) both in infants and children.
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General Information

Contains

Nimesulide (50mg)+ Paracetamol (125mg)

Marketer

Raphael Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
NSD Plus Suspension image
NSD Plus Suspension image

Your child’s medicine at a glance

NSD Plus Suspension works by blocking the action of a chemical messenger that is known to cause fever and inflammation. Adhere to the prescribed dose, time, and way while giving this medicine to your child. It can be given orally before or after meals. However, it is best to give this medicine to your child after meals as this will prevent the chance of developing an upset stomach. Try giving it at a fixed time so that it becomes a part of your child’s daily routine and helps prevent missing a dose.

If your child vomits within 30 minutes of taking this medicine, give the same dose again but do skip it if it's time for the next dose. Avoid giving more than the recommended dose for fast relief as that may cause unwanted effects in your child. Complete the full dose of the medicine even if your child feels better after a few doses because stopping the medicine in between may worsen the condition.

Your child may exhibit side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea after taking this medicine. These side effects are temporary and are likely to subside once your child’s body adapts to the medicine. In case they persist or become bothersome for your child, do consult your child’s doctor on a priority basis.


Note: As per the Ministry of Health and Family Welfare, NSD Plus Suspension is banned for children under 12 years of age.

Uses of NSD Plus Suspension in children

Benefits of NSD Plus Suspension for your child

Pain relief
NSD Plus Suspension is a combination of two medicines that belong to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of NSD Plus Suspension in children

NSD Plus Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of NSD Plus
  • Allergy
  • Nausea
  • Vomiting
  • Diarrhea
  • Increased liver enzymes

How can I give NSD Plus Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. NSD Plus Suspension is to be taken with food.

How NSD Plus Suspension works

NSD Plus Suspension comprises two active ingredients: Nimesulide and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever, and inflammation (redness and swelling).

Quick tips

  • Maintain a log of your child's temperature. If you do not see any improvement, contact your child's doctor for advice.
  • Give plenty of fluids to your child, if diarrhea occurs as a side-effect.
  • If your child exhibits signs of inflammation like redness or swelling,try placing an ice-pack over the affected area to reduce redness and swelling.
  • Never give any other medicine formulation containing paracetamol along with this medicine as that may lead to serious side effects.
  • Stop the medicine and consult your child’s doctor in case your child exhibits allergic rash or stomach pain soon after taking this medicine.
  • If NSD Plus Suspension does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.

Safety advice

Kidney

Kidney

CAUTION
NSD Plus Suspension should be used with caution in patients with kidney disease. Dose adjustment of NSD Plus Suspension may be needed. Please consult your doctor.
However, the use of NSD Plus Suspension is not recommended in children with severe kidney disease.
Liver

Liver

CAUTION
NSD Plus Suspension should be used with caution in patients with liver disease. Dose adjustment of NSD Plus Suspension may be needed. Please consult your doctor.
Discuss with your doctor thoroughly before giving NSD Plus Suspension to your child. Regular monitoring of Liver Function Tests (LFT) is recommended while your child is taking this medicine.

Frequently asked questions

No, it is not recommended to alter the dose of the medicine without consulting a doctor. While increasing the dose without proper judgment may lead to toxicity, decreasing it may cause recurrence of symptoms. So, for best results, speak to your child’s doctor if you feel a change in dose may be needed.
Your doctor will prescribe the dose according to your child’s condition and body weight. Stick to the prescribed dosing schedule as that is the best way to ensure the safe and complete recovery of your child.
NSD Plus Suspension should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all medicines out of the reach and sight of children to avoid any accidental intake.
No. NSD Plus Suspension cannot be given to everyone in the same dose. The doctor decides the appropriate dose of NSD Plus Suspension based on the child’s age and body weight.
You may be required to give NSD Plus Suspension to your child for a few days to weeks, depending upon the severity of the infection.If your child continues to feel unwell even after completion of the full prescribed course of the medicine, consult your child’s doctor as soon as possible.
Although NSD Plus Suspension is well-tolerated by children, if you notice your child experiencing any intolerable episodes like persistent vomiting, body swelling, decreased urine frequency, or serious allergic reaction, rush to your doctor on an immediate basis.
NSD Plus Suspension is a combination of two medicines: Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
NSD Plus Suspension is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if your physician has advised you to do so.
Yes, the use of NSD Plus Suspension can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice any signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
The use of NSD Plus Suspension is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should also be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.
Yes, NSD Plus Suspension can be taken with Vitamin B-complex preparations. While NSD Plus Suspension helps to relieve pain, Vitamin B-complex helps to correct the vitamin deficiency that might be causing your symptoms.
No, NSD Plus Suspension preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
NSD Plus Suspension contains Nimesulide and Paracetamol and both these medicines are known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.
No, you should avoid taking a higher than the recommended dose of NSD Plus Suspension as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Nimesulide [Amendments to the Summary of Product Characteristics and Package Leaflet]. [Accessed 10 Feb. 2021] (online) Available from:
  2. Chandra J, Kumar Bhatnagar S. Antipyretics in children. Indian J Pediatr. 2002;69:69-74. [Accessed 10 Feb. 2021] (online) Available from:
  3. National Health Service. Paracetamol for children (including Calpol). [Accessed 10 Feb. 2021] (online) Available from:
  4. Health Navigator, New Zealand. Paracetamol for children. [Accessed 10 Feb. 2021] (online) Available from:
  5. Best Practice e-Journal. Paracetamol dosing for children in primary care. [Accessed 10 Feb. 2021] (online) Available from:
  6. The Royal Children’s Hospital Melbourne. Pain relief for children – paracetamol and ibuprofen. [Reviewed Jul. 2020]. [Accessed 10 Feb. 2021] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Raphael Pharmaceuticals Pvt Ltd
Address: 558 GALI NO 1JANAKPURI LUDHIANA PUNJAB PB 000000 IN

Vendor Details

Country of origin: India

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