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MRP: Rs. 40 for 1 packet(s) (5 ML eye drop each)
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Composition for NIZOLINE Z


food interaction for NIZOLINE Z

alcohol interaction for NIZOLINE Z

pregnancy interaction for NIZOLINE Z

lactation interaction for NIZOLINE Z

There is no data available. Please consult doctor before consuming the drug.
Nizoline z 0.056%/0.01% eye drops may cause excessive drowsiness and calmness with alcohol.
Nizoline z 0.056%/0.01% eye drops may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Naphazoline is used to treat congestion/ clogging of nose or stuffy nose or as an accompaniment to treatment of sinusitis (inflammation of the hollow areas of the skull called sinuses around the nose).

How it works

Naphazoline nitrate belongs to a class of medication called alpha 2 agonist. It works by temporarily narrowing swollen blood vessels and reduces swelling of mucous membrane in the nose to relieve congestion or irritation.

Common side effects

Blurred vision, Headache, Increased intraocular pressure, Dilatation of the pupil of the eye, Tingling sensation


Chlorpheniramine is used to relieve symptoms of  runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu and allergies due to food and insect bites and hay fever.

How it works

Chlorpheniramine belongs to class of medications called antihistamines. It acts by blocking a natural chemical (histamine) that your body makes during an allergic reaction. Histamine is responsible for many symptoms of allergy. 

Common side effects

Nausea, Constipation, Drowsiness, Dry mouth, Dry throat, Dry skin, Headache, Inability to empty the urinary bladder, Loss of appetite, Nasal congestion, Chest congestion, Vomiting


8 Substitutes
Sorted By
  • MIL 0.056%/0.01% EYE DROPS
    (10 ML eye drop in packet)
    Sun Pharma Laboratories Ltd
    Rs. 5.90/ML of eye drop
    Rs. 59
    save 26% more per ML of eye drop
  • OPTIHIST 0.056%/0.01% EYE DROP
    (5 ML eye drop in packet)
    Entod Pharmaceuticals Ltd
    Rs. 9.60/ML of eye drop
    Rs. 48
    pay 20% more per ML of eye drop
  • OPTI ZEE 0.056%/0.01% EYE DROP
    (10 ML eye drop in packet)
    Jawa Pharmaceuticals Pvt Ltd
    Rs. 5.24/ML of eye drop
    Rs. 52.36
    save 35% more per ML of eye drop
    (10 ML eye drop in packet)
    FDC Ltd
    Rs. 3.95/ML of eye drop
    Rs. 39.50
    save 51% more per ML of eye drop
  • RED-RID PLUS 0.056%/0.01% EYE DROPS
    (10 ML eye drop in packet)
    Yash Pharma Laboratories Pvt Ltd
    Rs. 4.46/ML of eye drop
    Rs. 44.55
    save 44% more per ML of eye drop

Expert advice for NIZOLINE Z

• Seek medical advice if the symptoms persist or worsen after 3 days of treatment.
• Avoid prolonged use of medication as it may affect normal mucosal layer of nose and can cause loss of sensation of smell. 
• Seek immediate medical attention if you experience chest pain, fast/ irregular heart beat; severe headache, sweating, blurred vision, ringing in ears, anxiety, confusion, or breathlessness.
• Tell your doctor if you are or planning to become pregnant or are breastfeeding.
• Should not be given to patients allergic to naphazoline nasal or any of its ingredients.
• Should not be given to children < 12 years
• Should not be given to patients with heart disease, diabetes, depression, disorders related to thyroid glands.
• Should not be given to patients with high blood pressure and taking medication for the same.

Frequently asked questions for NIZOLINE Z


Q. Is Naphazoline safe?
Naphazoline is safe if taken at prescribed dose and duration as advised by your doctor.


Q. Does chlorpheniramine or chlorpheniramine maleate cause increase in blood pressure/ drowsy/non drowsy/sedating/get you high/keep you awake/sleepiness/make you tired/weight gain?
Chlorpheniramine causing these side effects is common or rare. Always consult your doctor, if you experience any of these side effects.
Q. Is chlorpheniramine like Benadryl?
No, chlorpheniramine is different from Benadryl.
Q. Is chlorpheniramine prescription?
Yes, it is available with doctor’s prescription only.
Q.Can I take chlorpheniramine or chlorpheniramine maleate with Panadol/ cetirizine /Zyrtec/ Allegra/ warfarin/ diphenhydramine/ ibuprofen/Claritin/guaifenesin/Benadryl?
Yes, but taking other medicines may alter the effects of chlorpheniramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does chlorpheniramine contain aspirin?
No, it does not contain aspirin in it. Chlorpheniramine is a different drug than aspirin.


Content on this page was last updated on 14 October, 2015, by Dr. Varun Gupta (MD Pharmacology)