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NIGRAIN PLUS 40 MG/5 MG TABLET

Tablet
MRP: Rs. 50 for 1 strip(s) (10 tablets each)
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Composition for NIGRAIN PLUS

Propranolol(40 mg),Flunarizine(5 mg)

food interaction for NIGRAIN PLUS

alcohol interaction for NIGRAIN PLUS

pregnancy interaction for NIGRAIN PLUS

lactation interaction for NIGRAIN PLUS

food
alcohol
pregnancy
lactation
Avoid Nigrain plus 40 mg/5 mg tablet with high-fat meals such as olive oil, nuts & seeds (Brazil nuts), dark chocolate, butter and meat.
UNSAFE
Nigrain plus 40 mg/5 mg tablet may cause excessive drowsiness and calmness with alcohol.
Taking Propranolol with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
UNSAFE
Nigrain plus 40 mg/5 mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION for NIGRAIN PLUS

Propranolol(40 mg)

Uses

Propranolol is used in the treatment of angina (chest pain), arrhythmias (abnormal heart beat), heart attack, increased blood pressure , anxiety and migraine.

How it works

Propranolol belongs to a class of medications called beta blockers. Propranolol works by blocking the action of certain natural chemicals in the body (such as epinephrine) that affect the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

Common side effects

Altered sleep, Bradycardia, Bronchospasm, Cardiac conduction abnormalities, Decreased sexual function, Decreased libido, Shortness of breath, Fatigue, Gastrointesinal symptoms, Increased glucose level in blood, Decreased blood pressure, Ischemia
Flunarizine(5 mg)

Uses

Flunarizine is used to prevent migraine.

How it works

Migraine headaches are thought to result from the dilatation of blood vessels in the head. Flunarizine works by constricting (narrowing) these blood vessels, thus relieving the migraine headache.

Common side effects

Constipation, Depression, Drowsiness, Increased appetite, Irregular menstrual cycle, Running nose, Nasal congestion

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Expert advice for NIGRAIN PLUS

  • Propranolol may cause dizziness and lightheadedness. To avoid this, get up slowly after sitting or lying down.
  • The Propranolol may affect your blood sugar and cover up the symptoms of low blood sugar if you have diabetes.
  • Propranolol may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid the use of tobacco.
  • Consult your doctor whether to continue Propranolol before any scheduled surgery.
  • It is not the first-choice treatment for high blood pressure according to the latest guidelines, except if you have a heart failure or heart disease.
  • Adults over the age of 65 may be at greater risk for the side-effects.
  • Your doctor may recommend a change in the lifestyle to lower your blood pressure. It may include:
     
    • Maintain a normal body weight (body mass index, 18.5-24.9 kg/m2).
    • Consume fruits, vegetables, low-fat dairy products, and reduce saturated-total fat.
    • Reduce daily dietary sodium intake as much as possible, ideally to 65 mmol/day (1.5 g/day sodium or 3.8 g/day sodium chloride).
    • Regular aerobic physical activity (at least 30 minutes/day, most days of the week).
    • Limit alcohol consumption to less than or equal to 2 drinks per day (1oz or 30ml ethanol eg 24oz beer, 10 oz wine, or 3 oz 80-proof whiskey).

Frequently asked questions for NIGRAIN PLUS

Propranolol

Q.What is betacap tr, inderal, and ciplar?
These are various brand (proprietary) names for propranolol medicine. Propranolol is a beta blocker drug which works to correct the heart rhythm

Q.Is propranolol safe?
Propranolol belongs to beta blocker class and works on heart rhythm so caution has to be observed before usage. Always ask your doctor or pharmacist for advice before taking propranolol. Propranolol is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is propranolol addictive?
No. Propranolol doesn’t seem to have habit forming potential

Q.Is propranolol MAO inhibitor or a statin?
No. Propranolol belongs to a medical class called beta blockers and works to correct abnormal heart rhythm along with other uses

Q.Is propranolol safe for long term use?
Yes, it can be used for long term based on indication

Q.Is propranolol available over the counter?
No. Propranolol is available only when a valid prescription is produced

Q.Is propranolol used to treat anxiety?
Yes. Propranolol can be used to mitigate tremors associated with the anxiety

Q.Is propranolol used for migraines?
In certain situations, propranolol has proved to be effective in preventing migraine attacks but additional data is required to support this usage.

Flunarizine

Q.What is flunarizine dihydrochloride/flunarizine hydrochloride/flunarizine 5 mg used for?
These are the names of drugs containing flunarizine and used for the treatment of preventing migraine attacks

Q.Does flunarizine cause weight gain?
Yes, it may cause weight gain. Always consult your doctor, if you experience this side effect

Q.Does flunarizine work?
Flunarizine works at prescribed dose and duration for the treatment of preventing migraine attacks as advised by your doctor

Q.How long does flunarizine take to work?
It depends on disease severity and lot of other factors.

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Content on this page was last updated on 11 January, 2015, by Dr. Varun Gupta (MD Pharmacology)