Propranolol + Flunarizine

Information about Propranolol + Flunarizine

Propranolol + Flunarizine Uses

Propranolol+Flunarizine is used for Prevention of migraine and Migraine.

How Propranolol + Flunarizine works

Propranolol + Flunarizine is a combination of two medicines: Propranolol and Flunarizine, which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).

Common side effects of Propranolol + Flunarizine

Weight gain, Slow heart rate, Tiredness, Depression, Drowsiness, Abnormal dreams, Cold extremities
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated
15 Apr 2020 | 12:15 PM (UTC)

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Expert advice for Propranolol + Flunarizine

  • You have been prescribed Propranolol + Flunarizine for prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get sufficient sleep and avoid stress
  • It should be taken at night-time before going to bed.
  • It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Propranolol + Flunarizine affects you.
  • keep taking it regularly every day, even if you don't have any symptoms.

Frequently asked questions for Propranolol + Flunarizine

Propranolol + Flunarizine

Q. Can Propranolol+Flunarizine be used for the treatment of a migraine headache?

No, Propranolol+Flunarizine does not help in relieving a migraine headache that has already started. It can only be used for preventing any new episode of migraine headaches.

Q. In which conditions is the use of Propranolol+Flunarizine contraindicated?

Use of Propranolol+Flunarizine is considered to be harmful for patients with allergy to any of the ingredients or excipients of this medicine. This medicine contains propranolol, so its use should be avoided in patients with asthma, slow heart rate, abnormal heart rhythms, or heart conditions like AV block or sick sinus syndrome. Since this medicine also contains flunarizine, the use of this medicine should be avoided in patients with the history of depression or Parkinson's disease.

Q. Can I stop taking Propranolol+Flunarizine when my symptoms are improved?

Propranolol+Flunarizine is given as a prophylactic treatment for the prevention of migraine headaches. Do not stop taking this medicine until advised by your doctor as it may cause your migraine episodes to return. This medicine contains propranolol and a sudden withdrawal of propranolol may cause sweating, shaking, irregular or fast heartbeat, worsening of underlying angina or heart attack. You must take Propranolol+Flunarizine exactly as advised by your doctor.

Q. What are the instructions for the storage and disposal of Propranolol+Flunarizine?

Keep Propranolol+Flunarizine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.


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