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Nicip Plus Tablet is a combination medicine that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)
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General Information

Contains

Nimesulide (100mg)+ Paracetamol (325mg)

Marketer

Cipla Ltd

Storage

Store below 25°C
The content is shown in English
Nicip Plus Tablet image
Nicip Plus Tablet image
Nicip Plus Tablet image
Nicip Plus Tablet image

Product introduction

Nicip Plus Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, and increased liver enzymes. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcers or bleeding in your stomach, high blood pressure, or any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Nicip Plus Tablet

  • Pain relief : Nicip Plus Tablet helps relieve pain in conditions such as headache, body ache, muscle pain, toothache, menstrual cramps, and minor injuries.

Benefits of Nicip Plus Tablet

Pain relief
Pain and inflammation can occur due to injury or conditions affecting the joints and muscles. Nicip Plus Tablet helps reduce pain, inflammation, and swelling. This helps relieve discomfort in conditions such as arthritis, muscle pain, and other short-term painful conditions. It improves movement and supports better daily functioning.

Side effects of Nicip Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nicip Plus
  • Nausea
  • Vomiting
  • Diarrhea
  • Increased liver enzymes

How to use Nicip Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nicip Plus Tablet should be taken with or after food.

How Nicip Plus Tablet works

Nicip Plus Tablet is a combination of two medicines: Nimesulide and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).

All substitutes for Nicip Plus Tablet

For information purposes only. Consult a doctor before taking any medicine.

Nedolide-P Tablet

by Leeford Healthcare Ltd
₹1.72/tablet
58% cheaper
<h3 class=bodySemiBold>Nedolide-P Tablet</h3>

Nimucet 100mg/325mg Tablet

by Intas Pharmaceuticals Ltd
₹3.56/tablet
13% cheaper
<h3 class=bodySemiBold>Nimucet 100mg/325mg Tablet</h3>

Nodard Plus Tablet

by Cipla Ltd
₹3.65/tablet
11% cheaper
<h3 class=bodySemiBold>Nodard Plus Tablet</h3>

Nimucet Gold 100mg/325mg Tablet

by Intas Pharmaceuticals Ltd
₹3.68/tablet
10% cheaper
<h3 class=bodySemiBold>Nimucet Gold 100mg/325mg Tablet</h3>

Nicip-P Tablet

by Cipla Ltd
₹5.88/tablet
43% costlier
<h3 class=bodySemiBold>Nicip-P Tablet</h3>

Quick tips

  • Take Nicip Plus Tablet with food to reduce the risk of stomach irritation.
  • Nicip Plus Tablet may cause dizziness or sleepiness, so avoid driving or operating machinery until you know how it affects you.
  • Avoid alcohol while taking Nicip Plus Tablet, as it may increase drowsiness and the risk of liver problems.
  • Do not take Nicip Plus Tablet with other medicines containing paracetamol unless advised by your doctor.
  • Avoid taking Nicip Plus Tablet with other NSAIDs unless your doctor recommends it.
  • Use Nicip Plus Tablet only for the duration prescribed, as prolonged or excessive use may increase the risk of liver-related side effects.
  • Stop taking Nicip Plus Tablet and seek medical attention if you notice yellowing of the skin or eyes, which may indicate liver problems.
  • Watch for warning signs such as severe stomach pain or black/tarry stools, and seek medical attention if they occur.
  • Inform your doctor if you have a history of liver disease before taking Nicip Plus Tablet.
  • Stop using Nicip Plus Tablet and consult your doctor if rash, swelling, or signs of an allergic reaction occur.
  • Consult your doctor if pain or fever persists despite taking Nicip Plus Tablet.
  • Do not increase the dose or extend the duration of Nicip Plus Tablet without medical advice.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Nicip Plus Tablet.
Pregnancy

Pregnancy

UNSAFE
Nicip Plus Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Nicip Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Nicip Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Nicip Plus Tablet in patients with kidney disease. Please consult your doctor.
Use of Nicip Plus Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Nicip Plus Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Nicip Plus Tablet is a medicine used for short-term relief of pain, fever, and inflammation. Your doctor may prescribe it for conditions such as a toothache, body pain, joint pain, muscle pain, or pain related to injuries. It works by reducing pain signals and inflammation in the body, which helps relieve discomfort. However, Nicip Plus Tablet only helps control symptoms and does not treat the underlying cause of pain. Because it contains strong pain-relieving ingredients, it should be taken only under a doctor’s supervision and not used for long periods without medical advice.
Nicip Plus Tablet is usually prescribed for short-term pain relief. If your pain improves, you may be able to stop taking it. However, if your doctor has advised you to take it for a specific period or for a particular condition, you should continue it as directed. Always follow your doctor’s instructions before stopping the medicine.
Nicip Plus Tablet may cause side effects such as nausea, vomiting, stomach discomfort, dizziness, or tiredness in some people. Taking the medicine with food or milk may help reduce stomach upset. Most people do not feel sleepy while taking it, but some may feel light-headed or weak. Drinking enough fluids may help if you feel unwell. Consult your doctor if these symptoms persist or if you experience severe vomiting, dizziness, or unusual discomfort.
Nicip Plus Tablet should not be taken by people who are allergic to this medicine or to other similar pain relievers known as NSAIDs. It is also not recommended for individuals with stomach ulcers or bleeding, severe liver disease, kidney problems, heart failure, or uncontrolled high blood pressure unless advised by a doctor. The medicine may carry a risk of liver injury, especially with repeated use or when combined with alcohol. Always inform your doctor about your medical history before taking Nicip Plus Tablet.
Yes, Nicip Plus Tablet can usually be taken with vitamin B-complex supplements. While Nicip Plus Tablet helps relieve pain, vitamin B-complex may help correct vitamin deficiencies that sometimes contribute to symptoms such as nerve pain or fatigue. However, it is always best to consult your doctor before combining medicines or supplements.
Nicip Plus Tablet should not be taken for stomach pain without consulting a doctor. The medicine may increase the risk of stomach irritation and could worsen certain underlying stomach conditions, such as gastritis or ulcers. If you have persistent stomach pain, seek medical advice rather than self-medicating.
Yes, Nicip Plus Tablet may affect the liver if it is taken in higher-than-recommended doses or used for a long time. The risk increases if you drink alcohol, already have liver disease, or take other medicines that contain similar ingredients. Stop taking the medicine and seek medical help if you notice symptoms such as yellowing of the skin or eyes, dark urine, severe tiredness, or unusual weakness.
Nicip Plus Tablet should generally be avoided during pregnancy unless a doctor specifically advises it. Certain anti-inflammatory pain medicines can affect pregnancy and the baby, particularly during the later stages. If you experience pain during pregnancy, consult your doctor so that a safer treatment option can be recommended.
While taking Nicip Plus Tablet, avoid drinking alcohol because it increases the risk of liver damage. Do not take other medicines that contain paracetamol or similar pain-relieving ingredients at the same time unless advised by your doctor. If you are prone to acidity, avoid taking the medicine on an empty stomach and try to eat light meals while using it. Staying well hydrated may also help reduce discomfort.
Nicip Plus Tablet is not intended for long-term or daily use for chronic pain unless your doctor closely supervises the treatment. Repeated or prolonged use can increase the risk of liver problems and may hide the underlying cause of the pain. Chronic pain conditions often require proper evaluation and a long-term treatment plan. Consult your doctor for safer options rather than using Nicip Plus Tablet regularly for extended periods.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
  2. ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
  4. ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
  5. Nimesulide and paracetamol. Panchkula, Haryana: Biofield Pharma Pvt. Ltd.; [Accessed 12 Feb. 2026] (online). Available from:
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User feedback

Twice A Day
60%
Once A Day
40%
Pain relief
51%
Others
21%
Fever
15%
Headache
9%
Dental pain
2%
Excellent
48%
Average
36%
Poor
16%
No Side Effect
70%
Diarrhea
9%
Vomiting
7%
Increased liver enzymes
7%
Nausea
4%
With food
86%
With or without food
12%
Empty stomach
3%
Average
44%
Expensive
36%
Not Expensive
20%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Nicip Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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