Nexvir Z Tablet is a combination of antiretroviral medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It improves the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Nexvir Z Tablet can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed, as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.

The most common side effects of this medicine are headaches, diarrhea, nausea, abdominal pain, and rash. These side effects are generally temporary, but if they persist or become serious, inform your doctor. However, if you experience hypersensitivity, consult your doctor immediately. Drinking plenty of fluid can help you cope with the side effects, so stay hydrated.

Before starting the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any other health conditions. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to learn about safe sex methods to prevent transmission of HIV during intercourse.

Uses of Nexvir Z Tablet

Treatment of HIV infection

Benefits of Nexvir Z Tablet

In Treatment of HIV infection

Nexvir Z Tablet prevents the HIV from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves the quality of your life.

Nexvir Z Tablet is not a cure for HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. Take it exactly as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines.

Side effects of Nexvir Z Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nexvir Z

Rash
Headache
Abdominal pain
Muscle pain

How to use Nexvir Z Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nexvir Z Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nexvir Z Tablet works

Nexvir Z Tablet is a combination of three medicines: lamivudine, zidovudine, and nevirapine that work together to fight HIV by preventing the virus from multiplying in the body. Lamivudine and zidovudine belong to a class of medicines called nucleoside reverse transcriptase inhibitors (NRTIs). They work by blocking an enzyme called reverse transcriptase, which HIV needs to make more copies of itself. This helps slow down the spread of the virus. Nevirapine, on the other hand, is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It attaches to the same enzyme but differently, making it even harder for HIV to multiply. By working together, these three medicines help protect the immune system and lower the risk of complications.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Nexvir Z Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Nexvir Z Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Nexvir Z Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Nexvir Z Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Nexvir Z Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nexvir Z Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Nexvir Z Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Nexvir Z Tablet may be needed. Please consult your doctor.

What if you forget to take Nexvir Z Tablet?

If you miss a dose of Nexvir Z Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nexvir Z Tablet

₹21.8/Tablet

Duovir N Tablet

Cipla Ltd

₹23.57/tablet

8% costlier

Lazid N Tablet

Emcure Pharmaceuticals Ltd

₹19.4/tablet

11% cheaper

ZIDOLAM N 150 MG/300 MG/200 MG TABLET

Hetero Drugs Ltd

₹20.4/tablet

6% cheaper

Zidolam N N 150 mg/300 mg/200 mg Tablet

Hetero Drugs Ltd

₹18.47/tablet

15% cheaper

Lazid N Tablet

Emcure Pharmaceuticals Ltd

₹20.47/tablet

6% cheaper

Quick tips

Do not skip doses, as that can increase the risk of treatment failure. Make sure that you take all your doses at the correct time.
Nexvir Z Tablet may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine, or yellowing of the eyes or skin.
Do not stop taking Nexvir Z Tablet without your doctor’s advice.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta

Dermatology

You still need to be on ART even if the viral load is undetectable

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

Top Physicians

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4.2 ★

Dr. Jai Bhagwan Bansal

MBBS, MD, Fellowship, Fellowship, Fellowship

4.6 ★

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Lamivudine+Zidovudine+Nevirapine [Prescribing Information]. Goa: Cipla Ltd.; 2011. [Accessed 19 Apr. 2019] (online) Available from:
Lamivudine+zidovudine [EMC Label]. South Ruislip, Middlesex: Milpharm Limited; 2017. [Accessed on 10 Apr. 2019] (online) Available from:
Lamivudine [EMC Label]. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2018. [Accessed 10 Apr. 2019] (online) Available from:
Zidovudine [EMC Label]. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2018. [Accessed 31 Mar. 2019] (online) Available from:
Lamivudine, Nevirapine and Zidovudine [Drug Label]. Secunderabad, India: Matrix Laboratories Limited; 2008. [Accessed 16 Sep. 2024] (online) Available from:
Lamivudine, Nevirapine and Zidovudine [FDA Label]. Hyderabad, Telangana.:Hetero Labs Limited; 2021. [Accessed 11 Mar. 2025] (online) Available from:

Marketer details

Name: Nexus India

Address: H-1 Building, Flat No 1, Phase III, Chintamani Nagar, Bibvewadi, Pune 411037.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.