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18 Feb 2020 | 05:25 PM (IST)
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Nalox 400mcg Injection



Nalox 400mcg Injection is an opioid antagonist. It is used for the treatment of opioid toxicity. It helps to reverse the depressant effect on breathing, and on other parts of the body. It also helps to determine if a patient has taken the overdose of opioid.

Nalox 400mcg Injection is given as an injection into veins, muscle or under the skin by a doctor or nurse. It is advisable not to self-administer the injection. Your doctor or nurse will train your family member or caregiver about how to inject the medicine in case of an emergency. It is advisable to follow your doctor's advice while being on the treatment. 

The most common side effects of this medicine include injection site redness, dizziness, headache and increased or decreased blood pressure. Most of these usually go away within a short time of the injection. If you are bothered by them or they go on for longer, talk to your doctor or nurse. You should not drive if this medicine makes you feel dizzy. 

Before taking it, tell your doctor if you have heart problems, high blood pressure or high heart rate. This may affect your treatment. Pregnant or breastfeeding women should consult their doctor before taking this medicine.  Some other medicines you are taking may interfere with it, so make sure your doctor knows about all the other medicines you are using.

Uses of Nalox Injection

  • Opioid toxicity

Side effects of Nalox Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nalox

  • Dizziness
  • Injection site redness
  • Decreased blood pressure
  • Headache
  • High blood pressure

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Injection site redness
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.
  • Coping with Decreased blood pressure
    Get up slowly from a sitting or lying position. Try to avoid changing positions suddenly even in general. Try crossing your legs when you are sitting and wearing compression stockings. Drink plenty of water and try eating smaller, more frequent meals. Although salt is not good for everyone (and bad for some people), if you have low blood pressure increasing your intake of salt (sodium) can raise your blood pressure. Cut down the amount of alcohol you drink. If your blood pressure becomes very low, you should talk to your doctor.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with High blood pressure
    You can reduce your blood pressure by eating less salt, eating more fruit and vegetables, reducing the amount of alcohol you drink, being more active and losing weight. You could also reduce your caffeine intake (found in tea, coffee and cola drinks). Also, if you smoke, seek advice about quitting. High blood pressure can be treated with a range of different medicines. You should ask your doctor whether you need medication. Keep in touch with your doctor and get your blood pressure checked regularly.

How to use Nalox Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nalox Injection works

Nalox 400mcg Injection is an opioid antagonist. Opioid medicines are strong painkillers, which in high doses can cause life-threatening side effects such as difficulty in breathing. Nalox 400mcg Injection works by blocking the effects of opioids leading to reversal of these side effects.

Safety Advice

It is unsafe to consume alcohol with Nalox 400mcg Injection.
Nalox 400mcg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Nalox 400mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Nalox 400mcg Injection does not usually affect your ability to drive.
Nalox 400mcg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nalox 400mcg Injection may not be needed in these patients. Please consult your doctor.
There is limited information available on the use of Nalox 400mcg Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Nalox Injection?

If you miss a dose of Nalox 400mcg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Nalox 400mcg Injection
₹84.5/ml of Injection
Nex 400mcg Injection
Neon Laboratories Ltd
₹102/ml of Injection
21% costlier
Narcotan 400mcg Injection
Troikaa Pharmaceuticals Ltd
₹200/ml of Injection
137% costlier

Quick Tips

  • It is given as an injection into veins, muscle or under the skin by the healthcare professionals only.
  • Nalox 400mcg Injection might make you feel dizzy. If this happens, avoid driving or operating on machinery.
  • Inform the doctor if you are taking any pain killers, sleeping pills (sedatives), narcotic painkillers, or other medicines
  • Avoid consuming alcohol while taking the medicine as it can affect the working of the medicine.

Patient Concerns

Ferrous sulphate tablets toxicity
Dr. Megha Tuli
Obstetrics and Gynaecology
There is no toxicity as such. Please be specific in what respect are you asking.
Diazepam toxicity about 45 tablets
Dr. Ambrish Dharmadhikari
Rush immediately to emergency services
Do you have any questions related to Nalox 400mcg Injection ?

User Feedback


Q. Is naloxone a controlled substance?

No. Naloxone is not a controlled substance

Q. Is naloxone addictive?

No. Naloxone is not addictive

Q. Is naloxone water soluble?

Yes. Naloxone is soluble in water

Q. Is naloxone absorbed orally?

Yes. Naloxone is relatively well absorbed after oral administration. However, it undergoes extensive first-pass metabolism, making this route of delivery ineffective

Q. Is naloxone in subutex?

No. Naloxone is not present in subutex

Q. Does naloxone block tramadol?

No. naloxone does not block tramadol

Q. Does naloxone cause constipation?

No. Naloxone does not cause constipation

Q. Does naloxone reverse methadone?

Yes. Naloxone reverses the effects of methadone

Q. Does naloxone reverse ketamine?

No. Naloxone does not reverse the effect of ketamine as it is an anaesthetic agent

Q. Does naloxone block buprenorphine?

Naloxone does not block buprenorphine if it is taken in pill form, but when injected or snorted it will.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


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  2. Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 547-48.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 952-53.
  4. Naloxone hydrochloride dihydrate. King William Street, London: Advanz Pharma; 1990 [revised 30 Aug. 2012]. [Accessed 6 Apr. 2019] (online) Available from:External Link
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Manufacturer/Marketer Address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
We do not facilitate sale of this product at present


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