Information about Naloxone

Naloxone Uses

Naloxone is used in the treatment of opioid toxicity.

How Naloxone works

Naloxone is an opioid antagonist. Opioid medicines are strong painkillers, which in high doses can cause life-threatening side effects such as difficulty in breathing. Naloxone works by blocking the effects of opioids leading to reversal of these side effects.

Common side effects of Naloxone

Dizziness, Injection site redness, Arrhythmia (irregular heartbeats), Decreased blood pressure, Headache, High blood pressure
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 11:51 AM (UTC)

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Available Medicine for Naloxone

NaloxSamarth Life Sciences Pvt Ltd
841 variant(s)
NarcotanTroikaa Pharmaceuticals Ltd
45 to ₹2003 variant(s)

Expert advice for Naloxone

  • It is given as an injection into veins, muscle or under the skin by the healthcare professionals only.
  • Naloxone might make you feel dizzy. If this happens, avoid driving or operating on machinery.
  • Inform the doctor if you are taking any pain killers, sleeping pills (sedatives), narcotic painkillers, or other medicines
  • Avoid consuming alcohol while taking the medicine as it can affect the working of the medicine.

Frequently asked questions for Naloxone


Q. Is naloxone a controlled substance?

No. Naloxone is not a controlled substance

Q. Is naloxone addictive?

No. Naloxone is not addictive

Q. Is naloxone water soluble?

Yes. Naloxone is soluble in water

Q. Is naloxone absorbed orally?

Yes. Naloxone is relatively well absorbed after oral administration. However, it undergoes extensive first-pass metabolism, making this route of delivery ineffective

Q. Is naloxone in subutex?

No. Naloxone is not present in subutex

Q. Does naloxone block tramadol?

No. naloxone does not block tramadol

Q. Does naloxone cause constipation?

No. Naloxone does not cause constipation

Q. Does naloxone reverse methadone?

Yes. Naloxone reverses the effects of methadone

Q. Does naloxone reverse ketamine?

No. Naloxone does not reverse the effect of ketamine as it is an anaesthetic agent

Q. Does naloxone block buprenorphine?

Naloxone does not block buprenorphine if it is taken in pill form, but when injected or snorted it will.


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