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MD (Pharmacology), MBBS
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MD (Pharmacology), MBBS
Last updated on:
19 Aug 2019 | 05:05 PM (IST)
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Nales Plus 50mg/10mg Tablet


Overview

Introduction

Nales Plus 50mg/10mg Tablet is a combination of two medicines used to reduce excess fluid levels in the body while maintaining the potassium balance. It is used to treat edema (fluid overload) and some cases of hypertension. It is best to take this medicine in the morning along with food in order to avoid frequent urination at night time. This medicine may cause dehydration, so it is better to take plenty of fluids whole day. Regular monitoring of kidney function and electrolytes is important while using this medicine. This medicine may produce enlargement of breast in male patients as a side effect but it gets back to normal after the medicine is discontinued. Dizziness may occur as a side effect initially, but this improves with time.

Uses of Nales Plus Tablet

Nales Plus Tablet side effects

Common
  • Dehydration
  • Decreased magnesium level in blood
  • Decreased sodium level in blood
  • Increased blood uric acid
  • Breast enlargement in male
  • Decreased calcium level in blood

How to use Nales Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nales Plus 50mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nales Plus Tablet works

Nales Plus 50mg/10mg Tablet is a combination of two medicines: Spironolactone and Torasemide. These medicines act on different parts of your kidney to remove extra water and certain electrolytes, while maintaining the potassium balance in your body.

Nales Plus Tablet related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Nales Plus 50mg/10mg Tablet. Taking Torsamide with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Pregnancy
WEIGH RISKS VS BENEFITS
Nales Plus 50mg/10mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Nales Plus 50mg/10mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Nales Plus 50mg/10mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Kidney
CAUTION
Nales Plus 50mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nales Plus 50mg/10mg Tablet may be needed. Please consult your doctor.
Use of Nales Plus 50mg/10mg Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Nales Plus 50mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Nales Plus 50mg/10mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Nales Plus 50mg/10mg Tablet
₹8.25/Tablet
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save 46%
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4% costlier
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₹4.51/Tablet
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Expert Advice

  • Nales Plus 50mg/10mg Tablet helps removes excess water from your body.
  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away.
  • Your doctor may regularly monitor your blood pressure, kidney function and the level of salts such as potassium and sodium in your blood while you're taking this medication.

Patient Concerns

Questions Related to Nales Plus

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FAQs

Q. Can the use of Nales Plus cause dizziness?

Yes, the use of Nales Plus can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.

Q. Can the use of Nales Plus cause gout?

Yes, Nales Plus can cause gout. Nales Plus contains torasemide which can increase the blood uric acid levels by increasing its absorption from the kidneys. Increased uric acid levels can cause a gout attack. Inform your doctor if you have hyperuricemia (excess of uric acid in blood) or a history of gout before taking this medicine. Use of Nales Plus should be avoided in patients with gout.

Q. Can the use of Nales Plus cause dehydration (excessive loss of fluid)?

Yes, the use of Nales Plus can cause dehydration (excessive loss of fluid). The patient may experience dryness of the mouth, thirst, drowsiness, restlessness, muscle pain, weakness, tiredness, fall in blood pressure (hypotension), decreased urination (oliguria), increased heart rate (tachycardia), nausea and vomiting. Inform your doctor if you experience persistent problems while taking this medicine.

Q. Can the use of Nales Plus cause hyperkalemia (increased potassium levels)?

Yes, Nales Plus can cause hyperkalemia (increased potassium levels). This occurs more commonly in patients with underlying kidney disease or in patients taking excessive potassium in their diet. High potassium levels can cause fatal heart problems. It is very important to get electrolytes and kidney function tests done on a regular basis while you are taking this medicine.

Q. What are the contraindications to the use of Nales Plus?

The use of Nales Plus should be avoided in patients with hypersensitivity to torasemide, sulfonylureas or spironolactone or any other ingredient of the product. The use of this medicine should also be avoided in patients with anuria, acute renal insufficiency, hepatic coma and pre-coma, low blood pressure (hypotension), cardiac arrhythmias, patients taking aminoglycosides or cephalosporins, kidney dysfunction due to drugs which cause renal damage, patients with high potassium levels (hyperkalemia), Addison's disease and in children with moderate to severe renal impairment.

Q. What is the storage condition for the Nales Plus?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Nales Plus?

Nales Plus is a fixed-dose combination of torasemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics and they help to remove excess fluid from the body. The use of this combination is advised in patients of congestive heart failure (heart failure leading to fluid accumulation in the lung and rest of the body), nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (edema) and swelling of the abdomen (ascites).

Q. Is it safe to use Nales Plus?

Yes, Nales Plus is safe to use in most of the patients. However, in some patients it may cause common side effects like dizziness, dehydration, decreased sodium level in blood, breast enlargement in males, decreased magnesium level in blood, decreased calcium level in blood, increased blood uric acid. Inform your doctor if you experience any persistent problem while taking this medicine.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. MedIndia. Spironolactone. [Accessed 11 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Spironolactone Pregnancy and Breastfeeding Warnings. [Accessed 11 Apr. 2019] (online) Available from:External Link
  3. Torsemide. Leganes Spain: Roche Farma S.A.; 2010. [Accessed 11 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Proqol Healthcare Pvt. Ltd., No 6 , Shop No 5, 2nd Floor, Sneham Commercial complex, MTH Road, Padi, Chennai- 600050
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