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Nacyres Injection

Acetylcysteine (NA)
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Nacyres Injection is an antidote medication. It is used in the treatment of paracetamol overdose (when you may have taken too much paracetamol medicine). It protects your liver and helps to reduce the extent of the injury.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 13 Oct 2025 | 04:21 PM (IST)
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5 ml Injection
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General Information

The content is shown in English
Nacyres Injection image
Nacyres Injection image

Product introduction

Nacyres Injection is given as an injection under the supervision of a doctor. It must be injected within 8 hours of a paracetamol overdose. It can be given up to 24 hours, but the medicine’s effectiveness slows down when given after 24 hours of the overdose. Your doctor will decide how much you need to improve your symptoms. Always follow your doctor's advice while taking this medicine.


The most common side effects of this medicine include rash, urticaria, flushing, and itching. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.


Before taking this medicine, let your doctor know if you suffer from asthma, as close monitoring is required while taking this medicine. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Nacyres Injection

  • Treatment of Paracetamol toxicity

Benefits of Nacyres Injection

Treatment of Paracetamol toxicity
Nacyres Injection is an antidote medicine that prevents serious side effects if a person has taken more than the normal or recommended amount of a medicine called paracetamol. Paracetamol overdose may cause serious liver damage, which may even lead to liver failure. Rarely, an excessive overdose may lead to a coma. Nacyres Injection is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit from this medication.

Side effects of Nacyres Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nacyres
  • Rash
  • Red spots or bumps
  • Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Nacyres Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nacyres Injection works

Nacyres Injection is an antidote for paracetamol poisoning. It works by increasing the level of glutathione, an antioxidant that neutralizes the toxic products of paracetamol. Glutathione helps the liver safely break down and remove harmful substances formed when paracetamol is taken in excessive amounts. If glutathione levels drop too low, these toxic substances can cause severe liver damage. By restoring glutathione, Nacyres Injection protects liver cells and reduces the risk of serious harm.

Quick tips

  • Do not wait for symptoms to appear—seek medical help immediately after a suspected overdose.
  • Let your doctor know if you have asthma or a history of stomach ulcers, as precautions may be needed.
  • After treatment, follow-up blood tests may be required to check liver function.
  • Always keep paracetamol out of reach of children to prevent accidental overdose.
  • Nacyres Injection protects the liver from damage by the high levels of paracetamol.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nacyres Injection. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Nacyres Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

CAUTION
Nacyres Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Nacyres Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

SAFE IF PRESCRIBED
Nacyres Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nacyres Injection may not be needed in these patients. Please consult your doctor.
Liver

Liver

CAUTION
Nacyres Injection should be used with caution in patients with severe liver disease. Dose adjustment of Nacyres Injection may be needed. Please consult your doctor.

Frequently asked questions

Nacyres Injection is mainly used to treat paracetamol (acetaminophen) overdose. It helps protect the liver from serious damage by breaking down harmful substances formed when too much paracetamol is taken.
For best results, Nacyres Injection should be given as soon as possible—ideally within 8 hours of the overdose. It can still help if given up to 24 hours later, but the sooner it is given, the better the chances of preventing liver damage.
Nacyres Injection is usually given in a hospital through a drip (intravenous infusion) into a vein. The dose and duration depend on the amount of paracetamol taken and how long it has been since the overdose. The doctor will monitor closely during the treatment to ensure safety and effectiveness.

Fact Box

Chemical Class

N-Acylated Alpha Amino Acids

Habit Forming

No

Therapeutic Class

OTHERS

Action Class

Mucolytics

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 13-15.
  2. Acetylcysteine (N-Acetylcysteine). In: Hitchings A, Lonsdale D, Burrage D, et al., editors. The Top 100 Drugs: Clinical Pharmacology and Practical Pescribng. Churchil Livingstone Elsevier; 2015.
  3. Acetylcysteine [EMC Label]. Romford, Essex: Martindale Pharma; 2017. [Accessed 01 Apr. 2019] (online) Available from:
  4. Acetylcysteine [Prescribing Information]. Nashville, Tennessee: Cumberland Pharmaceuticals Inc.; 2013. [Accessed 31 Jan. 2019] (online) Available from:
  5. Acetylcysteine Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2018. [Accessed 09 Jun 2023] (online) Available from:
  6. Acetadote® (acetylcysteine) Injection [Package insert]. Nashville, TN: Cumberland Pharmaceuticals Inc.; 2006. [Accessed 10 Feb 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: La Renon Healthcare Pvt Ltd
Address: Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Nacyres Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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