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Composition for METOZ R

Ramipril(5 mg),Metolazone(2.5 mg)

food interaction for METOZ R

alcohol interaction for METOZ R

pregnancy interaction for METOZ R

lactation interaction for METOZ R

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Taking Metolazone with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
UNSAFE
Metoz r tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Metoz r tablet is probably safe to use during breastfeeding. Please consult your doctor.
SAFE

SALT INFORMATION for METOZ R

Ramipril(5 mg)

Uses

Ramipril is used in the treatment of increased blood pressure , heart failure, heart attack and diabetic kidney disease.

How it works

Ramipril relaxes blood vessels which lowers blood pressure and also reduces the workload of the heart.

Common side effects

Allergic reaction, Cough, Dizziness, Difficulty in swalloing, Shortness of breath, Facial swelling, Generalised swelling, Headache, Vomiting, Stomach upset
Metolazone(2.5 mg)

Uses

Metolazone is used in fluid retention (edema), heart failure, increased blood pressure and kidney stone.

How it works

Metolazone lowers blood pressure and swelling by increasing the amount of urine, which removes extra water and certain electrolytes from the body.

Common side effects

Nausea, Nerve injury, Orthostatic hypotension (low blood pressure), Palpitations, Petechiae (red or purple spot caused by bleeding into the skin), Increased sensitivity to light, Abdominal bloating, Acute gouty attacks, Joint pain, Blood vessel inflammation, Blurred vision, Bone marrow failure, Chest discomfort, Chest pain, Chills, Constipation, Dehydration, Depression, Diarrhoea, Dizziness, Drowsiness, Gastrointestinal discomfort, Fainting, Fatigue, Bleeding gums, Headache, Inflammation of liver, Pancreatic inflammation, Increased glucose level in blood, Increased uric acid level in blood, Impotence, Increased blood urea nitrogen, Increased creatine level in blood, Increased glucose in urine, Insomnia, Jaundice, Loss of appetite, Muscle cramp, Rash, Restlessness, Tarry stools, Unpleasant breath odour, Vertigo, Vomiting, Weakness, Abnormal sensation in skin, Decreased potassium level in blood, Decreased white blood cell count

SUBSTITUTES for METOZ R

No substitutes found

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Expert advice for METOZ R

  • Notify your doctor immediately if you are or planning to become pregnant during the administration of this medicine.
  • Notify the doctor if you have signs of recurrent infections (sore throat, chills, fever), these may be signs of neutropenia (unusually low number of cells called neutrophils, a type of white blood cells). 
     
  • Ramipril should be discontinued a day prior to any surgery.
  • Notify your doctor if you have rapid swelling of the lips, tongue, and throat that may affect breathing. This may occur in 1 out of 100 patients taking the Ramipril.
  • Your doctor may recommend a change in the lifestyle to lower your blood pressure. It may include:
    • Maintain a normal body weight (body mass index, 18.5-24.9 kg/m2). 
    • Consume fruits, vegetables, low-fat dairy products, and reduce saturated-total fat.
    • Reduce daily dietary sodium intake as much as possible, ideally to 65 mmol/day (1.5 g/day sodium or 3.8 g/day sodium chloride).
    • Regular aerobic physical activity (at least 30 minutes/day, most days of the week).
    • Limit alcohol consumption to less than or equal to 2 drinks per day (1oz or 30ml ethanol eg 24oz beer, 10 oz wine, or 3 oz 80-proof whiskey).
     
  • A persistent dry cough is common with Ramipril. Notify the doctor if the cough becomes bothersome. Do not take any cough medicines.
  • Ramipril may cause dizziness in the first few days of starting the treatment, especially after the first dose. To avoid this, take the Ramipril at bedtime, drink plenty of water and get up slowly after sitting or lying down.
  •  
    Avoid driving if you feel dizzy after consuming Ramipril.
  • Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.

Frequently asked questions for METOZ R

Ramipril

Q.Is ramipril a diuretic?
No, ramipril is not a diuretic It belongs to a class of drugs called ACE inhibitors (angiotensin converting enzyme inhibitors), mainly used to reduce high blood pressure

Q.Is ramipril safe?
Ramipril is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is ramipril or cardace a calcium channel blocker/alpha blocker/ beta blocker?
No, ramipril or cardace is an ACE inhibitor and shows no known effects on calcium channels or alpha receptors or beta receptors

Q.Is ramipril a nitrate or a statin?
Ramipril is neither a nitrate nor a statin. It is an ACE inhibitor used to treat high blood pressure

Q.What are Cardace / Ramistar/Hopace used for?
Cardace, Ramistar, Hopace are all trade names for the active drug ramipril. Ramipril is an ACE inhibitor used to treat high blood pressure

Q.Can I take ramipril with simvastatin/amlodipine/ Viagra/naproxen/prednisolone/ metformin/ Sudafed (pseudoephedrine-decongestant preparation)?
There are no known serious drug interactions between ramipril when taken with simvastatin/ amlodipine/ Viagra/naproxen/prednisolone/ metformin/Sudafed. However, consult your doctor about all medications currently taken before starting and while on ramipril

Q.Can I take ramipril with ibuprofen?
Ibuprofen can be taken with ramipril, however, it is known that ibuprofen and other NSAIDs may reduce the antihypertensive effects of ramipril. Consult your doctor about any medications currently taken before starting and while on ramipril

Q.Does ramipril cause coughing?
Yes, non-productive tickling cough, is one of the common side effects or ramipril

Q.Does ramipril cause frequent urination?
No, ramipril has no known effect on increasing the frequency of urination. It may rarely increase the urine output but not affect the frequency of urination

Q.Does ramipril cause itching?
Yes, ramipril may cause itching of skin. It is not very commonly observed

Q.Does ramipril cause an increase in potassium levels in the blood?
Yes, increased potassium levels is one a common side effects of ramipril

Q.Does ramipril cause depression?
Yes, ramipril may cause depression; however, it is not very commonly observed

Q.Does ramipril thin the blood?
No. ramipril has no known effect on blood thinning

Q.Is ramipril available in India?
Yes, ramipril is available in India with more than 100 brand names.

Metolazone

Q.Is metolazone potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic?
Metolazone belongs to the group of medicines called quinazoline and thiazide-like diuretic and it is not potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic

Q.Is metolazone discontinued?
No, metolazone is not discontinued

Q.Is metolazone stronger than Lasix?
Metolazone and furosemide (Lasix) belongs to same category of drugs (diuretics), but their effect may vary upon individual response

Q.Can you take metolazone with Lasix?
Metolazone and furosemide (Lasix) may sometimes be prescribed, but these combinations can lead to dehydration and electrolyte abnormalities. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required

Q.Does metolazone contain sulfa?
Yes, it contains sulfa. Chemically it is called as 7-chloro-2-methyl-4-oxo-3-o-tolyl-1, 2, 3, 4-tetrahydroquinazoline-6-sulfonamide

Q.Does metolazone get you high/ deplete potassium?
Metolazone causing the above side effects is uncommon or rare. However consult your doctor if you experience any of these side effects

Q.Does metolazone appear in breast milk?
Yes, metolazone gets excreted in breast milk. Patient should follow the advice of the doctor regarding its use

Q.How long does metolazone take to work?
It depends upon disease condition and lot of other factors. Patient should follow the advice of the doctor regarding its use.

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Content on this page was last updated on 01 February, 2016, by Dr. Varun Gupta (MD Pharmacology)