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METOLACTONE 2.5 MG/50 MG TABLET

Tablet
MRP: Rs. 46.65 for 1 strip(s) (10 tablets each)
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Composition for METOLACTONE

Metolazone(2.5 mg),Spironolactone(50 mg)

food interaction for METOLACTONE

alcohol interaction for METOLACTONE

pregnancy interaction for METOLACTONE

lactation interaction for METOLACTONE

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Taking Metolazone with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
UNSAFE
Metolactone 2.5 mg/50 mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Metolactone 2.5 mg/50 mg tablet is probably safe to use during breastfeeding. Please consult your doctor.
SAFE

SALT INFORMATION for METOLACTONE

Metolazone(2.5 mg)

Uses

Metolazone is used in fluid retention (edema), heart failure, increased blood pressure and kidney stone.

How it works

Metolazone lowers blood pressure and swelling by increasing the amount of urine, which removes extra water and certain electrolytes from the body.

Common side effects

Nausea, Nerve injury, Orthostatic hypotension (low blood pressure), Palpitations, Petechiae (red or purple spot caused by bleeding into the skin), Increased sensitivity to light, Abdominal bloating, Acute gouty attacks, Joint pain, Blood vessel inflammation, Blurred vision, Bone marrow failure, Chest discomfort, Chest pain, Chills, Constipation, Dehydration, Depression, Diarrhoea, Dizziness, Drowsiness, Gastrointestinal discomfort, Fainting, Fatigue, Bleeding gums, Headache, Inflammation of liver, Pancreatic inflammation, Increased glucose level in blood, Increased uric acid level in blood, Impotence, Increased blood urea nitrogen, Increased creatine level in blood, Increased glucose in urine, Insomnia, Jaundice, Loss of appetite, Muscle cramp, Rash, Restlessness, Tarry stools, Unpleasant breath odour, Vertigo, Vomiting, Weakness, Abnormal sensation in skin, Decreased potassium level in blood, Decreased white blood cell count
Spironolactone(50 mg)

Uses

Spironolactone is used in the treatment of increased blood pressure , heart failure, cirrhosis and low potassium.

How it works

Spironolactone lowers blood pressure and swelling by increasing the amount of urine, which removes extra water and certain electrolytes from the body. Spironolactone does this without loss of potassium from the body.

Common side effects

Abdominal pain, Abnormal vaginal bleeding, Bloody diarrhea, Breast tenderness, Breast enlargement, Dizziness, Drowsiness, Dry mouth, Fatigue, Headache, Hoarseness of voice, Increased hair growth, Impotence, Restlessness, Unsteadiness, Bloating, Vomiting, Absence of menstrual periods, Irregular menstrual cycle, Excessive thirst

SUBSTITUTES for METOLACTONE

No substitutes found

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Expert advice for METOLACTONE

  • Do not take metolazone tablets, if you are allergic (hypersensitive) to sulfa drugs, thiazides, any other medications, metolazone or any of the other ingredients of metolazone tablet.
  • Do not take metolazone, if you are unable to urinate; if you have precoma or are in a coma caused by severe liver disease; if you have kidney or liver problem.
  • Avoid using metolazone, if you are pregnant or breastfeeding.
  • Consult your doctor, if you have or ever had diabetes, gout, low blood sodium or potassium levels, systemic lupus erythematosus.
  • Avoid prolonged exposure to sunlight.
  • Do not drive or operate machinery after taking metolazone.

Frequently asked questions for METOLACTONE

Metolazone

Q.Is metolazone potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic?
Metolazone belongs to the group of medicines called quinazoline and thiazide-like diuretic and it is not potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic

Q.Is metolazone discontinued?
No, metolazone is not discontinued

Q.Is metolazone stronger than Lasix?
Metolazone and furosemide (Lasix) belongs to same category of drugs (diuretics), but their effect may vary upon individual response

Q.Can you take metolazone with Lasix?
Metolazone and furosemide (Lasix) may sometimes be prescribed, but these combinations can lead to dehydration and electrolyte abnormalities. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required

Q.Does metolazone contain sulfa?
Yes, it contains sulfa. Chemically it is called as 7-chloro-2-methyl-4-oxo-3-o-tolyl-1, 2, 3, 4-tetrahydroquinazoline-6-sulfonamide

Q.Does metolazone get you high/ deplete potassium?
Metolazone causing the above side effects is uncommon or rare. However consult your doctor if you experience any of these side effects

Q.Does metolazone appear in breast milk?
Yes, metolazone gets excreted in breast milk. Patient should follow the advice of the doctor regarding its use

Q.How long does metolazone take to work?
It depends upon disease condition and lot of other factors. Patient should follow the advice of the doctor regarding its use.

Spironolactone

Q.Is spironolactone an ACE inhibitor/thiazide diuretic/corticosteroid/steroid/ beta blocker?
No, spironolactone belongs to a class of medications called aldosterone receptor antagonists

Q.Is spironolactone safe?
Spironolactone is safe, if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is spironolactone over the counter drug?
No, it is available as prescription drug

Q.Is spironolactone used for weight control, birth control, for acne, loss of hair?
No, spironolactone is used in the treatment of failure of heart, resulting in fluid build-up in lungs or other body tissue (congestive cardiac failure), chronic liver disease (hepatic cirrhosis) with accumulation of fluid in peritoneum liver (ascites and edema), malignant ascites, nephrotic syndrome, diagnosis and treatment of primary aldosteronism

Q.What is spironolactone/Dytor plus/Aldactone?
Spironolactone/Dytor plus/Aldactone belongs to a class of medications called aldosterone receptor antagonists

Q.Can spironolactone/Dytor plus/Aldactone cause cancer, hair loss, depression, insomnia, lower blood pressure, constipation, increase estrogen, weight loss?
Spironolactone/Dytor plus/Aldactone can causes hair loss, increase estrogen constipation. Always consult your doctor about possible side effects

Q.Can i take spironolactone/Aldactone with ibuprofen/vitamins/ antibiotics/ phentermine/ metformin amoxicillin/ Adderall(amphetamine and dextroamphitamine/ Accutane (isotretinoin)/ Benadryl (diphenhydramine)/ Tylenol (acetaminophen)/ Lasix (furosemide)?
Indometacin may increase the diuretic effect of spironolactone. Patients should follow doctors advice regarding its use

Q.Does spironolactone affect birth control?
No, Always consult your doctor about possible effects.

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Content on this page was last updated on 17 March, 2015, by Dr. Varun Gupta (MD Pharmacology)