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Metacin Exs Tablet is a combination of two medicines used in the treatment of headache. It helps relieve headache by blocking the release of certain chemical messengers that causes headache.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 06 Jan 2026 | 04:52 PM (IST)
MRP ₹22.63
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Metacin Exs  Tablet image
Metacin Exs  Tablet image

Product introduction

Your doctor will advise how much Metacin Exs Tablet you need to take. It can be taken with or without food. You should take the medicine regularly while you do need it and try not to miss doses as it will become less effective. It should be used with caution in people who have any problems with their heart, kidneys, or liver.

Using this medicine may cause sleep problems (insomnia), nervousness, irritation, or restlessness. If you experience any of such side effects that do not go away or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. Do not consume alcohol when on treatment with this medicine as it may cause excessive sleepiness. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Metacin Exs Tablet

Benefits of Metacin Exs Tablet

Treatment of Headache
Metacin Exs Tablet is a painkiller used to treat headache. It works by blocking chemical messengers in the brain that tell us we have pain. By treating headache, it can help you carry out your daily activities and have a better quality of life. Take Metacin Exs Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

Side effects of Metacin Exs Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metacin Exs
  • Restlessness
  • Insomnia (difficulty in sleeping)
  • Nervousness
  • Irritation

How to use Metacin Exs Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metacin Exs Tablet may be taken with or without food.
Avoid Metacin Exs Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.

How Metacin Exs Tablet works

Metacin Exs Tablet is a combination of two medicines: Caffeine and Paracetamol. Caffeine narrows the blood vessels in the brain to reduce headache. Paracetamol is an analgesic (pain reliever) which works by blocking the release of certain chemical messengers that cause pain. Together, they relieve headache effectively.

Quick tips

  • Metacin Exs Tablet is used to get relief from headache.
  • You can take a dose of Metacin Exs Tablet every 4-6 hours if needed, up to four times a day. Remember to leave at least four hours between doses and do not take more than four doses in any 24-hour period.
  • Taking too much of this medicine can cause damage to your liver because of the presence of paracetamol in it.
  • Managing your stress levels well and taking 6-7 hours of sleep at night can help prevent a headache.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Metacin Exs Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Metacin Exs Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Metacin Exs Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Metacin Exs Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Metacin Exs Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, Metacin Exs Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.
Liver

Liver

CAUTION
Metacin Exs Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Metacin Exs Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Caffeine is often combined with paracetamol because it increases the effectiveness of paracetamol.
Contact your doctor immediately even if you feel well. An overdose of Metacin Exs Tablet can cause serious liver damage. Symptoms of liver damage are fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, and yellow skin or eyes.
Avoid using Metacin Exs Tablet for more than 2-3 days per week for headache. Its overuse can instead lead to the occurrence of a medicine-overuse headache.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Metacin Exs Tablet contains paracetamol. This medicine is known to cause harm to the liver in high doses. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal liver enzymes.

Fact Box

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User feedback

Fever
33%
Headache
33%
Others
17%
Migraine
17%
Excellent
75%
Average
25%
No Side Effect
100%
With food
75%
With or without food
25%
Not Expensive
67%
Expensive
25%
Average
8%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Chemosyn Limited
Address: 69-B , J-type area ,G.I.D.C. Industrial Estate,Near CNG Gas Station,Vapi- 396195

Vendor Details

Country of origin: India
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