Meswemb 200mg Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 14 Apr 2026 | 04:20 PM (IST)

Meswemb 200mg Injection is used to prevent ifosfamide-induced hemorrhagic cystitis (bleeding in the bladder that may be caused as a side effect due to treatment with a cancer chemotherapy drug called ifosfamide). However, it is not used to reduce the risk of bladder bleeding due to other medical conditions.

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General Information

Contains

Mesna (100mg/ml)

Marketer

Wembrace Biopharma Pvt. Ltd.

Storage

Store below 25°C

The content is shown in English

Product introduction

Meswemb 200mg Injection is given under the supervision of a doctor. The dose and duration of the treatment vary based on your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some common side effects of this medicine include nausea, headache, lightheadedness, lethargy, and abdominal pain. It is advised to drink at least 1 liter of fluid daily when you are on treatment with this medicine. You should seek immediate medical attention if you experience signs of severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking this medicine. Regular blood tests are required to check your blood cells along with the kidney, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have an autoimmune disorder, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Meswemb Injection

Treatment of Ifosfamide-induced hemorrhagic cystitis

Benefits of Meswemb Injection

Treatment of Ifosfamide-induced hemorrhagic cystitis
Ifosfamide-induced hemorrhagic cystitis is an inflammatory condition due to the use of a medicine called Ifosfamide that causes bleeding in the bladder. Meswemb 200mg Injection helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged area, prevents further damage, and stabilises your condition

How to use Meswemb Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Meswemb Injection works

Meswemb 200mg Injection helps to reduce the risk of inflammation and bleeding in the bladder, who receive ifosfamide (a medicine used to treat cancer).

Quick tips

Meswemb 200mg Injection is given as in injection or infusion under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
It is advisable to drink plenty of water to stay hydrated while taking this medicine.
Your doctor may get a regular urine and blood tests done to monitor your blood cell count (CBC).

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Meswemb 200mg Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Meswemb 200mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Meswemb 200mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Meswemb 200mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As patients undergoing treatment with Meswemb 200mg Injection may experience undesirable effects such as lightheadedness, lethargy, dizziness, and blurred vision which could affect the ability to drive.

Kidney

CAUTION

Meswemb 200mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Meswemb 200mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Why it is given with ifosamide or cyclophosphamise (Cytoxan)?

It is given along with the chemotherapy drug ifosfamide or cyclophosphamide to reduce the side effects of these drugs

Is mesna compatible with potassium chloride and doxorubicin?

Yes, Mesna is compatible with potassium chloride and doxorubicin

Is Meswemb 200mg Injection a chemotherapy drug?

Meswemb 200mg Injection is not a chemotherapy drug

Is Meswemb 200mg Injection cytotoxic?

No. Meswemb 200mg Injection is not cytotoxic drug. It is cytoprotective drug

Is Meswemb 200mg Injection a vesicant?

No, Meswemb 200mg Injection is not a vesicant.

Fact Box

Chemical Class

Organosulfonic acids

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Cytoprotective agents- Bladder

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 870-71.
Mesna. Thetford, Norfolk: Baxter Healthcare Ltd.; 2003 [revised Oct. 2014]. [Accessed 28 Jan. 2019] (Online) Available from:
Mesna. Los Angeles, California: American pharmaceutical partners; 2001. [Accessed 26 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wembrace Biopharma Pvt. Ltd.
Address: B-6/9,Commercial Complex Safdarjung Enclave, New Delhi-110029

Vendor Details

Country of origin: India

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