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MRP: Rs. 1076 for 1 vial(s) (1 injection each)
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Composition for MEROBAX SB

Meropenem(1000 mg),Sulbactam(500 mg)

food interaction for MEROBAX SB

alcohol interaction for MEROBAX SB

pregnancy interaction for MEROBAX SB

lactation interaction for MEROBAX SB

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Merobax sb 1000mg/500mg injection is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Meropenem(1000 mg)


Meropenem is used to treat bacterial infections of lung (pneumonia), brain (meningitis), urinary tract, abdomen, blood, skin and soft tissue. It is also used to treat lung and bronchial infections and infections during or after delivery. It may be used in the management of reduced white blood cells (neutropenic) patients with fever.

How it works

Meropenem belongs to a group of medicines called carbapenem beta-lactam antibiotics. It kills bacteria by inhibiting bacterial cell wall (outer coating of bacteria) formation. As a result, the bacterial cell wall is weakened and ruptures, thereby killing the bacteria.

Common side effects

Nausea, Numbness, Pale red skin, Itchy rash, Rash, Abdominal pain, Abnormal blood cell count, Application site pain, Application site inflammation, Burning sensation, Diarrhoea, Fungal infection of mouth, Fungal infection of vagina, Headache, Increased bilirubin in the blood, Increased blood platelets, Itching, Pricking sensation, Tingling sensation, Increased blood urea, Vomiting
Sulbactam(500 mg)


Sulbactam is used in combination with other antibiotics for treating certain bacterial infections. It is used to treat intraabdominal, gynecological, skin or soft tissue, and surgal infections, especially those developed in the hospital.

How it works

Sulbactam belongs to group of medicines called betalactamase Inhibitor with very weak action against bacteria.  Beta-lactamase inhibitors are available only in fixed combinations with specific penicillins (beta-lactam antibiotics) such as amoxicillin, ampicillin, piperacillin, and ticarcillin. It works by preventing destruction of beta-lactam antibiotics from chemicals released from bacteria and extends their spectrum of activity.

Common side effects

Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing


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Expert advice for MEROBAX SB

Meropenem is given as an injection directly into a vein by a doctor or nurse using water for injections or a suitable infusion fluid. Do not start or continue the meropenem and consult your doctor:
  • If you have kidney or liver problems.
  • If you have a history of seizures or central nervous system problems (e.g. brain lesions).
  • If you experience severe and persistent diarrhea after taking antibiotics.
  • If you are taking other drugs like probenecid, valproic acid, or oral anticoagulants like warfarin.
  • If you are pregnant, planning to become pregnant or breastfeeding.

Frequently asked questions for MEROBAX SB


Q. Is meropenem a penicillin, cephalosporin, or beta lactam drug?
Meropenem is not a penicillin or cephalosporin drug. It is a carbapenem beta-lactam antibiotic.
Q. Is meropenem safe?
Meropenem is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is meropenem dialyzable?
Yes, meropenem is dialyzable.
Q. Is meropenem compatible with vancomycin, or potassium?
Meropenem may be compatible with potassium or vancomycin. Please consult your doctor before taking the drug.
Q. Is meropenem nephrotoxic, vesicant or cause thrombocytopenia?
Meropenem may be nephrotoxic, vesicant, and may cause thrombocytopenia. Please consult your doctor if you experience these side effects.
Q. What organisms does meropenem cover?
Meropenem is active against gram-positive and gram-negative bacteria, aerobes as well as anaerobes. It is effective against enterococcus, streptococcus, and methicillin-sensitive Staphylococcus aureus (MSSA), but not effective against listeria or methicillin-resistant Staphylococcus aureus.


Q. Is sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor.
Q. What is sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins.
Q. Is sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.


Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)