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Meprenor Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 21 Sep 2025 | 05:34 PM (IST)
Meprenor Tablet is a combination of three medicines used to treat neuropathic pain. It works by decreasing pain by controlling calcium channel activity of the nerve cells. It also increases the level of chemical messengers in the brain that help in regulating the mood and protect nerve fibers.
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Meprenor Tablet is currently sold out
Same composition alternative:
Nervmax MNT 75mg/10mg/1500mcg Tablet
₹230₹255
14% cheaper alternative available from Alkem Laboratories
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Meprenor Tablet
Meprenor Tablet
strip of 10 tablets
₹269
₹304.69
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Same composition
Nervmax MNT 75mg/10mg/1500mcg Tablet
Nervmax MNT 75mg/10mg/1500mcg Tablet
strip of 10 tablets
Pregabalin (75mg) + Nortriptyline (10mg) + Methylcobalamin (1500mcg)
by Alkem Laboratories Ltd
Get in 60 mins
₹230
₹19.6 per tablet

₹196

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₹1200

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General Information

Contains

Pregabalin (75mg)+ Nortriptyline (10mg)+ Methylcobalamin (1500mcg)

Marketer

Necleous Pharmaceuticals

Storage

Store below 25°C
The content is shown in English
Meprenor Tablet image
Meprenor Tablet image
Meprenor Tablet image
Meprenor Tablet image

Product introduction

Meprenor Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by the doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may worsen your symptoms.

Some common side effects of this medicine include constipation, weight gain, and dryness in mouth. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. You must inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Meprenor Tablet

Benefits of Meprenor Tablet

Treatment of Neuropathic pain
Meprenor Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that are essential for improving nerve conduction.
Taking Meprenor Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

Side effects of Meprenor Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Meprenor
  • Constipation
  • Weight gain
  • Dizziness
  • Sleepiness
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Uncoordinated body movements
  • Decreased appetite
  • Difficulty in urination
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

How to use Meprenor Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Meprenor Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Meprenor Tablet works

Meprenor Tablet is a combination of three medicines: Pregabalin, Nortriptyline and Methylcobalamin. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

All substitutes for Meprenor Tablet

For information purposes only. Consult a doctor before taking any medicine.

Dubinor Tablet

by Integrace Pvt Ltd
₹26.4/tablet
2% cheaper
<h3 class=bodySemiBold>Dubinor Tablet</h3>

GB 29 Total Tablet

by Corona Remedies Pvt Ltd
₹27.1/tablet
1% costlier
<h3 class=bodySemiBold>GB 29 Total Tablet</h3>

Nervite Plus Tablet

by Macleods Pharmaceuticals Pvt Ltd
₹24.2/tablet
10% cheaper
<h3 class=bodySemiBold>Nervite Plus Tablet</h3>

Pregabanyl NTM Tablet

by Leeford Healthcare Ltd
₹16.5/tablet
39% cheaper
<h3 class=bodySemiBold>Pregabanyl NTM Tablet</h3>

Nervmax MNT 75mg/10mg/1500mcg Tablet

by Alkem Laboratories Ltd
₹23/tablet
14% cheaper
<h3 class=bodySemiBold>Nervmax MNT 75mg/10mg/1500mcg Tablet</h3>

Quick tips

  • Meprenor Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
  • Inform your doctor if you are taking any other pain-relieving medicines.
  • Inform your doctor if you have a history of seizures.
  • Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
  • Along with taking Meprenor Tablet, your doctor might advise you to undergo physiotherapy to get relief rom pain.

Safety advice

Alcohol

Alcohol

UNSAFE
Meprenor Tablet may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Meprenor Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Meprenor Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Meprenor Tablet may cause side effects which could affect your ability to drive.
As Meprenor Tablet may affect your alertness which may affect your ability to drive.
Kidney

Kidney

CAUTION
Meprenor Tablet should be used with caution in patients with kidney disease. Dose adjustment of Meprenor Tablet may be needed. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Meprenor Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Meprenor Tablet may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Meprenor Tablet is a combination of three medicines: pregabalin, nortriptyline, and methylcobalamin. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
No, you should not stop taking Meprenor Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Meprenor Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
Meprenor Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Yes, Meprenor Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
The use of Meprenor Tablet can affect the sexual life of both men and women. Most commonly observed problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Meprenor Tablet.
Serious side effects because of Meprenor Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
An initial benefit with Meprenor Tablet may be seen after 2 weeks of the treatment. However, it may take around 2-3 months or more to see full benefits and even.
If you forget to take the scheduled dose of Meprenor Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect. If you are not sure what to do, consult your about how to manage a situation like this.
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Meprenor Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Meprenor Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Meprenor Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
You may need to see your doctor regularly if you have started to take Meprenor Tablet. However, you must consult your doctor if the advised dosage of Meprenor Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Keep your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
Yes, Meprenor Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Meprenor Tablet after the expiry date.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Pregabalin. Sandwich, Kent: Pfizer Limited; 2009 [revised July 2018]. [Accessed 24 Apr. 2019] (online) Available from:
  2. Pregabalin (Prolonged Release), Methylcobalamin and Nortriptyline Hydrochloride [Patient Information Sheet]. Haridwar, Uttarakhand: Synokem Pharmaceutical Ltd,; 2022. [Accessed 28th Sept. 2023] (online) Available from:
  3. Pregabalin+ Nortriptyline [Prescribing Information]. Mumbai, Maharashtra: Alkem Laboratories Limited. [Accessed 28th Sept. 2023] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Necleous Pharmaceuticals
Address: UNIT NO 140 1ST FLOOR VARDHMAN FORTUNE MALL GT KARNAL ROAD INDUSTRIAL AREA AZADPUR DELHI 110033 9717129594

Vendor Details

Country of origin: India

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