Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
User feedback
FAQs

Author Details

Written By

Dr. Sakshi Jain

MS, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

17 Jan 2026 | 02:11 AM (IST)

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Home>Melanorm-MS>melanorm-ms cream

Melanorm-MS Cream

Prescription Required

Marketer

Unimarck Pharma India Ltd

SALT COMPOSITION

Hydroquinone (2% w/w) + Mometasone (0.1% w/w) + Tretinoin (0.025% w/w)

Storage

Store below 25°C

68% cheaper alternative available with same salt composition

Click here to view all substitutes

Product introduction

Melanorm-MS Cream is a dermatological medicine used for the short-term, intermittent treatment of moderate to severe melasma of the face. It works by reducing excess melanin formation and improving skin turnover, helping lighten dark facial patches.

Melanorm-MS Cream is for external use only. Melanorm-MS Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not use this medicine more than the recommended dose.

The common side effects of this medicine include dryness, redness, and a stinging sensation at the application site. If these side effects or any other symptoms that you think are because of this medicine persist for a longer duration, consult your doctor.

Melanorm-MS Cream should be used only under medical supervision and for short-term, intermittent treatment. It is meant for external use on the face only and should not come into contact with the eyes, mouth, or mucous membranes. Sun exposure or UV light should be strictly avoided during treatment, as this can cause repigmentation of treated areas. Use sunscreen regularly.

Its safety has not been established in pregnancy or in children below 12 years, and caution is advised in breastfeeding women. Treatment should be stopped if severe irritation, hypersensitivity, or worsening of skin symptoms occur.

Uses of Melanorm-MS Cream

Treatment of Melasma

Benefits of Melanorm-MS Cream

In Treatment of Melasma

Melasma is a condition that causes dark patches on the face, commonly associated with sun exposure and hormonal factors. Melanorm-MS Cream helps improve melasma by reducing excess melanin formation and supporting skin cell turnover, which allows dark patches to fade more evenly. When used for short-term, intermittent treatment under medical supervision and combined with proper sun protection, it helps improve the appearance of facial melasma.

Side effects of Melanorm-MS Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Melanorm-MS

Application site reactions (burning, irritation, itching and redness)

How to use Melanorm-MS Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Melanorm-MS Cream works

Melanorm-MS Cream is a combination of three medicines: Hydroquinone, Mometasone, and Tretinoin—used for the treatment of melasma of the face. Hydroquinone reduces excess melanin formation in the skin, which helps lighten dark patches. Mometasone is a corticosteroid that helps reduce inflammation, redness, and irritation associated with treatment. Tretinoin is a vitamin A derivative that promotes skin cell turnover, helping melanin to disperse more evenly. Together, these actions help improve the appearance of melasma when used for short-term, intermittent treatment under medical supervision.

Safety advice

Alcohol

No interaction found/established

Pregnancy

UNSAFE

Melanorm-MS Cream is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

SAFE IF PRESCRIBED

Melanorm-MS Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

What if you forget to take Melanorm-MS Cream?

If you miss a dose of Melanorm-MS Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Melanorm-MS Cream

₹14.07/gm of Cream

ELOsone-HT Cream

Leeford Healthcare Ltd

₹4.52/gm of cream

68% cheaper

Ultrabrite Cream

Leeford Healthcare Ltd

₹4.52/gm of cream

68% cheaper

Skinshine Cream

Cadila Pharmaceuticals Ltd

₹6/gm of cream

57% cheaper

Cadila Skinshine Cream

Cadila Pharmaceuticals Ltd

₹7.07/gm of cream

50% cheaper

Skinbrite Cream

Galpha Laboratories Ltd

₹8.47/gm of cream

40% cheaper

View all substitutes

Quick tips

Melanorm-MS Cream is used for the short-term treatment of mild to moderate melasma.
It helps reduce scars, marks, blemishes, and dark circles under the eyes.
It should always be used along with sun-avoidance measures, like using sunscreens and wearing protective clothing.
Apply and massage gently till the cream is fully absorbed, once daily at night.
Initial improvement may be seen in just 2 weeks; full results generally appear after 2-3 months of regular use.
Do not apply to broken or infected areas of skin. Discontinue use if you experience irritation or an allergy and consult your doctor.
Do not use it for longer than 6-8 weeks without consulting your doctor.

Fact Box

Habit Forming

Therapeutic Class

DERMA

Patient concerns

hi doctor, a black spot starts to appear in my nose a year back. still its there. i have attached the photo of my nose here. is there any medicine for this sir?

Dr. Banashree Majumdar

Dermatology

Hello Ms PATIENT are having melasma, which is multifactorial disease. As per now do strict sun protection. Apply sunban ultra from 8am -4pm and kojiglo cream at night for 3 weeks.

Creame for fine lines of under eye

Dr. Banashree Majumdar

Dermatology

Dear Ms Smita, apply Cetaphil moisturising cream twice daily

User feedback

Patients taking Melanorm-MS Cream

Once A Day

100%

What are you using Melanorm-MS Cream for?

Melasma

44%

Hyperpigmenta*

28%

Acne

12%

Others

Skin disorder*

*Hyperpigmentation, Skin disorders

How much was the improvement?

Excellent

46%

Average

44%

Poor

10%

What were the side-effects while using Melanorm-MS Cream?

No Side Effec*

50%

Skin irritati*

25%

Muscle disord*

25%

*No Side Effect, Skin irritation, Muscle disorders

How do you take Melanorm-MS Cream?

Empty stomach

33%

With food

33%

With or witho*

33%

*With or without food

Please rate Melanorm-MS Cream on price

Average

50%

Not Expensive

30%

Expensive

20%

FAQs

What is Melanorm-MS Cream used for?

Melanorm-MS Cream is used for the short-term, intermittent treatment of moderate to severe melasma of the face. It is prescribed when dark facial patches do not respond adequately to other treatments and must be used along with sun protection measures.

Can Melanorm-MS Cream be used for pigmentation on other parts of the body?

No. This medicine is indicated only for melasma of the face. It should not be used on other body areas unless specifically advised by a doctor.

How should I use Melanorm-MS Cream?

Melanorm-MS Cream is usually applied once daily in the evening, as directed by your doctor. A thin layer should be applied only to the affected facial areas. The duration of treatment depends on response and should be decided by a physician.

How long does it take to see improvement?

Many patients may notice visible improvement within 8 weeks, although results can vary. Treatment should not be continued longer than advised, even if improvement is slow.

Is sun protection necessary while using Melanorm-MS Cream?

Yes. Sun exposure or UV light can cause repigmentation of treated areas. Strict sun avoidance, regular use of sunscreen, and protective measures are essential during treatment.

Can Melanorm-MS Cream be used for long-term treatment?

No. Melanorm-MS Cream is meant for short-term, intermittent use only. Prolonged or continuous use may increase the risk of side effects and should be avoided.

Who should not use Melanorm-MS Cream?

Melanorm-MS Cream should not be used by people who are allergic to hydroquinone, tretinoin, or mometasone furoate. It is also not recommended during pregnancy, in children below 12 years, or without medical supervision.

What should I avoid while using Melanorm-MS Cream?

Avoid contact with the eyes, mouth, and mucous membranes. Avoid excessive sun exposure and UV light. Do not apply more than prescribed, and do not use other skin-lightening or irritating products unless advised by your doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Hydrocortisone [EMC SmPC]. Clonmel, Tipperary: Pinewood Laboratories Limited; 2018. [Accessed 04 Apr. 2019] (online) Available from:
Tretinoin [Prescribing Information]. Manati, Puerto Rico: Janssen Ortho LLC; 2014. [Accessed 03 Apr. 2019] (online) Available from:
Hydroquinone+Tretinoin+Mometasone Furoate [Prescribing Information]. Mehsana, India: Torrent Pharmaceuticals.

Marketer details

Name: Unimarck Pharma India Ltd

Address: SCO 264SECTOR 32 CHANDIGARH UT CH 000000 IN

Country of origin: India
Expires on or after: December, 2026

A licensed vendor partner from your nearest location will deliver Melanorm-MS Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP₹223.1 5% OFF

₹211

Inclusive of all taxes

15.0 gm in 1 tube

The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (such as shipping fee, handling and/or platform fee etc.) will be clearly disclosed before you complete your purchase.