Megarab-D SR Capsule is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux). It works by relieving the symptoms of acidity such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort.
Megarab-D SR Capsule is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are diarrhea, stomach pain, dryness in the mouth, headache, flatulence, and weakness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.
Before you start taking this medicine it is important to inform your doctor if you are suffering from kidney or liver disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
In Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Megarab-D SR Capsule reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective. Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
In Treatment of Peptic ulcer disease
Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Megarab-D SR Capsule reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.
Side effects of Megarab-D Capsule SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Megarab-D
Pharyngitis
Cough
Headache
Diarrhea
Dizziness
Inflammation of the nose
Abdominal pain
Vomiting
Weakness
Insomnia (difficulty in sleeping)
Nausea
Constipation
Flatulence
Nasal congestion (stuffy nose)
Fundic gland polyps
Back pain
How to use Megarab-D Capsule SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megarab-D SR Capsule is to be taken empty stomach.
How Megarab-D Capsule SR works
Megarab-D SR Capsule is a combination of two medicines: Domperidone and Rabeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Rabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Megarab-D SR Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Megarab-D SR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Megarab-D SR Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Megarab-D SR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Megarab-D SR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Megarab-D SR Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Megarab-D SR Capsule should be used with caution in patients with liver disease. Dose adjustment of Megarab-D SR Capsule may be needed. Please consult your doctor. Use of Megarab-D SR Capsule is not recommended in patients with moderate and severe liver disease.
What if you forget to take Megarab-D Capsule SR?
If you miss a dose of Megarab-D SR Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Megarab-D SR Capsule for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
You have been prescribed Megarab-D SR Capsule for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
My cough is not getting cured since 4-6 months. Tried some doctors, their medicines work for some time and the dry cough starts again. Though it happens occasionally, but i still cough
Dr. Shubhra Chandan Pradhan
ENT
It can be allergic cough or acid reflux disease. Can't give more opinion without seeing
Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen
Dr. Saurav Arora
Homeopathy
Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly,
As soon as I go to sleep I start coughing and it stops after i drink water. it feels like as if something has stuck in the throat. it is happening for the past few days. Same happen if i do not drink water for some time. Please help me with the solution.
Dr. Shubhra Chandan Pradhan
ENT
It can be due to acid reflux. Take tab pan D morning and zintac bed time . Try this
What is the reason and perfect treatment for acid reflux?
Dr. Satyam S. Bhavsar
Physician
Hello, Welcome to 1mg consulting, Myself Dr.Satyam, MBBS.For acid reflux , take TAB.PAN-D twice a day half hour before food for 2 weeks.SYR.DIGENE 2 spoons before bedtime for 2 weeks.Avoid spicy food & fasting.Hope this helps.Happy to help you. Have a nice day :-)
Megarab-D SR Capsule is a combination of two medicines: Domperidone and Rabeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.
What are the contraindications of Megarab-D SR Capsule?
The use of Megarab-D SR Capsule is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Can the use of Megarab-D SR Capsule cause dry mouth?
Yes, the use of Megarab-D SR Capsule can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.
Can the use of Megarab-D SR Capsule cause diarrhea?
Yes, the use of Megarab-D SR Capsule can cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and if you notice any signs of dehydration, like less urination with dark colored and strong-smelling urine.
What is the recommended storage condition for Megarab-D SR Capsule?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Is it safe to use Megarab-D SR Capsule?
Yes, Megarab-D SR Capsule is safe for most of the patients. However, in some patients it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
What is the best time to take Megarab-D SR Capsule?
It is best to take Megarab-D SR Capsule before the first meal of the day or on an empty stomach.
Can the use of Megarab-D SR Capsule cause abnormal heartbeat?
Yes, the use of Megarab-D SR Capsule can increase the risk of developing irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.
What is Megarab-D SR Capsule?
Megarab-D SR Capsule is a combination of two medicines: Domperidone and Rabeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.
What are the contraindications of Megarab-D SR Capsule?
The use of Megarab-D SR Capsule is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Can the use of Megarab-D SR Capsule cause dry mouth?
Yes, the use of Megarab-D SR Capsule can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.
Can the use of Megarab-D SR Capsule cause diarrhea?
Yes, the use of Megarab-D SR Capsule can cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and if you notice any signs of dehydration, like less urination with dark colored and strong-smelling urine.
Is it safe to use Megarab-D SR Capsule?
Yes, Megarab-D SR Capsule is safe for most of the patients. However, in some patients it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
What is the best time to take Megarab-D SR Capsule?
It is best to take Megarab-D SR Capsule before the first meal of the day or on an empty stomach.
Can the use of Megarab-D SR Capsule cause abnormal heartbeat?
Yes, the use of Megarab-D SR Capsule can increase the risk of developing irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.
What is the recommended storage condition for Megarab-D SR Capsule?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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References
Domperidone+Rabeprazole [Product Monograph]. Mumbai, India: GlaxoSmithKline Pharmaceuticals Limited; 2009. [Accessed 13 May 2021] (online) Available from:
CiplaMed. Rabeprazole sodium + Domperidone [Prescribing Information]. Mumbai, India: Cipla Ltd.; 2020. [Accessed 13 May 2021] (online) Available from:
Rabeprazole (GR) and Domperidone (SR) Capsules [Drug Label]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 13 May 2021] (online) Available from:
Rabeprazole sodium and Domperidone sustained release capsules [Patient Information Sheet]. Solan, Himachal Pradesh: Torrent Pharmaceuticals Ltd.; 2022. [Accessed 13 May 2021] (online) Available from:
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.