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Megamentin Syrup

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 14 Apr 2026 | 04:21 PM (IST)
Megamentin Syrup is an antibiotic medicine that helps treat bacterial infections of the ear, nose, throat, chest, lungs, teeth, skin, and urinary tract. It is capable of killing bacteria that have become resistant to other therapies and thus also helps treat tuberculosis that is resistant to other treatments.
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Megamentin Syrup
bottle of 50 ml Syrup
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Megamentin Syrup image
Megamentin Syrup image

Product introduction

You can give Megamentin Syrup to your child with or without food. It is better to give it with food as that helps increase absorption and decrease the risk of stomach upset. The doctor may prescribe giving it two to three times a day. Medicine dose depends on the severity of the infection, its type, and your child’s body weight and age. So, stick to the dose, time, and way prescribed. If your child vomits the medicine within 30 minutes of intake, let the child calm down and repeat the dose. Do not double dose if it's the time for the next dose.

Megamentin Syrup may cause vomiting, diarrhea, nausea, abdominal pain, and allergy. These side effects should diminish on their own. But, in case they persist or start bothering your child, you must not delay speaking to your child’s doctor.

Share your child’s entire medical history with the doctor, including any previous episode of allergy, heart problem, a blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, liver impairment, and kidney malfunction. This information will assist the doctor in making dose alterations and in planning your child’s overall treatment.

Uses of Megamentin Syrup

Benefits of Megamentin Syrup

Treatment of Bacterial infections
Megamentin Syrup contains two different medicines, Amoxycillin and Clavulanic Acid, that work together to kill the bacteria that cause infections. Amoxycillin works by stopping the growth of bacteria. Clavulanic Acid reduces resistance and enhances the activity of Amoxycillin against bacteria.

This combination medicine can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin, teeth, joints, and bones. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Megamentin Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Megamentin
  • Abdominal pain
  • Allergy
  • Vomiting
  • Nausea
  • Diarrhea
  • Mucocutaneous candidiasis

How to use Megamentin Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Megamentin Syrup should be taken with or after food.

How Megamentin Syrup works

Megamentin Syrup is an antibiotic. It has two active agents, amoxycillin and clavulanic acid. Amoxycillin works by preventing the formation of the bacterial protective covering (cell wall) essential for the survival of the bacteria. Whereas, clavulanic acid serves a special purpose of inhibiting an enzyme (beta-lactamase) that is produced by resistant bacteria. This makes the combination of amoxycillin and clavulanic acid an effective line of treatment for many types of infections.

Quick tips

  • Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
  • Your child may have a bitter taste in the mouth after the intake of Megamentin Syrup. Eating citrus fruit or sipping plenty of water or fruit juice may help.
  • Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
  • Never give Megamentin Syrup until and unless prescribed by the doctor. You must also never share your child’s medicine with anyone else even if they show similar symptoms.
  • Do not give Megamentin Syrup to treat common cold and flu-like symptoms caused by viruses.
  • Never save medicine for future illnesses. It cannot be said whether the same medicine will work on future infections.
  • Check ‘expiry’ before giving Megamentin Syrup to your child. Immediately discard all the expired medicines.
  • Stop Megamentin Syrup immediately if your child develops an itchy rash, facial swelling, or breathing difficulty. Report to the doctor without any delay. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Megamentin Syrup. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Megamentin Syrup during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Megamentin Syrup during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Megamentin Syrup does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Megamentin Syrup should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
The dose also needs to be reduced in neonates and infants due to incompletely developed renal function.
Liver

Liver

CAUTION
Megamentin Syrup should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is recommended while you are taking this medicine

Frequently asked questions

Megamentin Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Megamentin Syrup. Also, check with your child’s doctor before giving any medicine to your child.
Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.
With prolonged therapy, the doctor may monitor kidney and liver function tests periodically to keep a check on your child’s condition.
No, do not stop giving this medicine to your child unless the full course of the treatment is complete, even if you feel better. The symptoms may improve before the infection is completely cured. Hence, continue giving the medicine for the due course as it may still be showing beneficial effects.
Yes, Megamentin Syrup may cause diarrhea. It is an antibiotic that kills harmful bacteria. In addition to that, the medicine may also affect the helpful bacteria in your child’s stomach and cause diarrhea. In case of diarrhea, encourage your child to drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less frequency of urination with dark-colored and strong-smelling urine. Do not give any other medicine to your child without consulting a doctor.
Most of the time, bacterial infections do not follow viral infections. In fact, giving antibiotics in viral infection can increase your child’s risk of developing side effects. So, use antibiotics only after consulting with your child’s doctor.
Yellow or green mucus in the nose does not mean that antibiotics are needed. During a common cold, it is normal for mucus to thicken up and change from clear to yellow or green. Symptoms often last for 7-10 days.
You must call your child’s doctor right away if your child experiences serious allergic reactions (breathing problems, skin rashes), gastrointestinal infections (diarrhea), and liver damage (weakness, paleness, vomiting). Though rare, these side effects are serious and need an expert’s attention.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
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