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Matiz Plus Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 12 Feb 2026 | 12:28 PM (IST)
Matiz Plus Tablet is used to treat irritable bowel syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). It prevents the sudden spasm of muscles to relieve stomach pain and cramps. It also promotes easy passage of gas to reduce stomach discomfort.
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General Information

Contains

Mebeverine (135mg)+ Chlordiazepoxide (5mg)

Marketer

Tas Med India Pvt Ltd

Storage

Store below 25°C
The content is shown in English
Matiz Plus Tablet image
Matiz Plus Tablet image
Matiz Plus Tablet image
Matiz Plus Tablet image

Product introduction

Matiz Plus Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.


There is limited data on the side effects of Matiz Plus Tablet. Let your doctor know if you experience any symptoms while taking the medicine. They can suggest ways to treat or manage the side effects.


Before you start Matiz Plus Tablet, let your doctor know if you have any medical conditions. Let your doctor also know about all the medications you are taking, as some medicines may interact with Matiz Plus Tablet. Pregnant or breastfeeding women should consult their doctor before taking Matiz Plus Tablet to ensure safety.

Uses of Matiz Plus Tablet

Benefits of Matiz Plus Tablet

Irritable bowel syndrome
Irritable Bowel Syndrome (IBS) is a chronic condition that causes abdominal pain, bloating, gas, and irregular bowel movements. Matiz Plus Tablet offers dual relief: It relaxes the intestinal muscles to ease cramps, discomfort, and helps reduce anxiety, which often worsens IBS symptoms. This medicine improves digestive comfort and helps restore regular bowel habits, making daily life more manageable.

Side effects of Matiz Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Matiz Plus
  • Limited data available

How to use Matiz Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Matiz Plus Tablet may be taken with or without food.

How Matiz Plus Tablet works

Matiz Plus Tablet is a combination of two medicines: Mebeverine and Chlordiazepoxide.

Quick tips

  • You have been prescribed Matiz Plus Tablet for the treatment of pain and other discomfort associated with irritable bowel syndrome.
  • Do not take Matiz Plus Tablet at least 2 hours before or after taking other medicines as it may interact with other medicines.
  • Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Matiz Plus Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Matiz Plus Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Matiz Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Matiz Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
As Matiz Plus Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Matiz Plus Tablet in patients with kidney disease. Please consult your doctor.
Caution is advised in patients with severe kidney disease.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Matiz Plus Tablet in patients with liver disease.
Caution is advised in patients with severe liver disease.

Frequently asked questions

Yes, Matiz Plus Tablet may cause withdrawal symptoms. Do not stop taking Matiz Plus Tablet all of a sudden. Stopping Matiz Plus Tablet suddenly can cause seizures, shaking, stomach and muscle cramps, vomiting and sweating. Consult with your doctor before stopping Matiz Plus Tablet.
No, avoid drinking alcohol while you are taking Matiz Plus Tablet. Drinking alcohol can increase the risk of side effects like drowsiness or sleepiness.
Yes, Matiz Plus Tablet may make you feel drowsy or sleepy. Avoid driving, operating any machines, working at heights or participating in potentially dangerous activities at the start of your treatment. Inform your doctor if you experience such episodes while taking this medicine.
Matiz Plus Tablet should not be taken along with opioid-like substances as it contains chlordiazepoxide. Use of opioids along with chlordiazepoxide may cause excessive sedation (state of calm or sleep), respiratory depression and eventually coma or death. Inform your doctor about all the medicines that you are taking if you are advised to take Matiz Plus Tablet.
Both Mebeverine and Chlordiazepoxide show different symptoms of overdose. Chlordiazepoxide can cause sleepiness, reflexes, confusion and coma. Whereas, Mebeverine can cause CNS excitability which is mild and reversible. Inform the doctor in case you take a higher dose and any of these symptoms appear.
Yes, the use of Matiz Plus Tablet can cause constipation. Eat high-fiber foods like vegetables, fruits and cereals, and drink plenty of water. Exercise regularly by engaging in activities like swimming, jogging or taking a walk. Consult a doctor if the constipation persists for a long duration.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Yes

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Complete Blood Count

References

  1. Daniluk J, Malecka-Wojciesko E, Skrzydlo-Radomanska B, et al. The Efficacy of Mebeverine in the Treatment of Irritable Bowel Syndrome-A Systematic Review. J Clin Med. 2022;11(4):1044. [Accessed 22 Nov. 2025]. Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Tas Med India Pvt Ltd
Address: Plot No. 45, N.T.M., Sector -26, Chandigarh

Vendor Details

Country of origin: India

Lab tests offered by us

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