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MD Pharmacology, MBBS
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Mahacef-Plus 100 Tablet

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Your child’s medicine at a glance

Mahacef-Plus 100 Tablet is an antibiotic medicine that treats bacterial infections that may affect your child’s eyes, ears, nose, throat, lungs, skin, bone and joints, gastrointestinal tract, and urinary tract. It can also be used in treating typhoid fever in children and adolescents.

Give Mahacef-Plus 100 Tablet to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. The dose and duration depend upon the type and severity of the infection, your child’s age, and body weight, so stick to the dose, time, and way prescribed by the doctor. If your child vomits within 30 minutes of intake, repeat the same dose but do not double dose if it's time for the next dose.

Do not give this medicine to your child in case of cold and flu symptoms. Such symptoms are almost always a result of viral infections, and antibiotics are ineffective in killing viruses. Antibiotics are given in cough and flu symptoms only when the doctor detects any underlying secondary bacterial infection.

This medicine may have some minor and temporary side effects such as vomiting, diarrhea, nausea, abdominal pain, and allergy. These side effects will disappear once your child’s body adapts to the medicine. However, if they persist or become bothersome for your child, report to the doctor without any delay.

Share your child’s complete medical history with your child’s doctor. Make sure the doctor knows if your child has or had any previous episode of allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.

Uses of Mahacef-Plus 100 Tablet in children

Benefits of Mahacef-Plus 100 Tablet for your child

In Treatment of Typhoid fever

Typhoid fever spreads through the intake of contaminated food and water. Children who have typhoid and do not require hospital admission can be well managed with Mahacef-Plus 100 Tablet at home because of its excellent activity against organisms that cause typhoid fever.

In Treatment of Bacterial infections

Mahacef-Plus 100 Tablet is a combination of two different antibiotics that work together, in different ways, to treat various bacterial infections. Cefixime works by stopping the growth of bacteria and kills them. Ofloxacin prevents multiplication and repair of infection causing bacteria and prevents further spread of the infection.

This combination medicine can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Mahacef-Plus 100 Tablet in children

Mahacef-Plus 100 Tablet does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Mahacef-Plus

  • Loss of appetite
  • Allergy

How can I give Mahacef-Plus 100 Tablet to my child?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mahacef-Plus 100 Tablet is to be taken with food.

How Mahacef-Plus Tablet works

Mahacef-Plus 100 Tablet contains two antibiotics. Cefixime works by preventing the formation of the bacterial protective covering (cell wall) while ofloxacin directly interacts with the genetic material of bacteria. As a consequence, the infection-causing bacteria stop growing further and the spread of the infection is successfully arrested.

Safety advice

Kidney
CAUTION
Mahacef-Plus 100 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mahacef-Plus 100 Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Mahacef-Plus 100 Tablet is safe to use in patients with liver disease. No dose adjustment of Mahacef-Plus 100 Tablet is recommended.
However, consult your child’s doctor before giving $med_name to your child in case of a severe form of liver disease.

What if I forget to give Mahacef-Plus 100 Tablet to my child?

Unless your child’s doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next dose. Do not give the double dose to catch up and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Mahacef-Plus 100 Tablet
₹11.2/Tablet
Zenflox-Plus 100 Tablet
Mankind Pharma Ltd
₹10.7/tablet
4% cheaper
₹8.63/tablet
23% cheaper
Wanixim OF 100mg/100mg Tablet
Wannock Pharmaceuticals
₹9.02/tablet
19% cheaper
Cefiquik O 100mg/100mg Tablet
Torrent Pharmaceuticals Ltd
₹7.69/tablet
31% cheaper
₹9.6/tablet
14% cheaper

Quick tips

  • Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
  • Give this medicine with food to avoid an upset stomach.
  • Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
  • Do not give any calcium, magnesium, iron, vitamin, or antacid within 2 hours of taking Mahacef-Plus 100 Tablet as these can affect the absorption of the medicine.
  • Conditions like common cold and flu are caused by viruses. Never use this medicine for such conditions.
  • Only give Mahacef-Plus 100 Tablet to your child for their current infection. Never save medicine for future illnesses.
  • Stop this medicine and immediately report to your child’s doctor in case your child develops an itchy rash, facial swelling, or breathing difficulties while taking this medicine.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

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I am suffering from Typhoid, please suggest the medicine and doses
Dr. Pushkar Mani
Physician
ok take MAHACEF PLUS twice daily for 7 days , paracetamol 500 mg twice daily for 7 days, capsule Zevit twice daily for 10 days, Omez d 20mg in empty stomach once daily for 10 daysremember dont leave the dosage of MAHACEF PLUS in between even your fever is gone, u have to complete the course of 7 days without missing any dosage
can i will take mahacef 200 with febrex plus for cold and flu and body pain fever
Dr. Sunil Sekhri
Diabetology
Antibiotics are given after a clinical check up is done to a assess the severity and extent and type of infection.Take team inhalation, Tab Pyrigesic 500 1 tab SOS, Tab Loridin 1 Od x 3 days
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User feedback


FAQs

Q. What if I give too much of Mahacef-Plus 100 Tablet by mistake?

An extra dose of Mahacef-Plus 100 Tablet is unlikely to do harm. However, you must still be vigilant because overdoses may cause unwanted side effects and may even worsen your child’s condition. If you think you have given too much of Mahacef-Plus 100 Tablet to your child, speak to a doctor immediately.

Q. Are there any possible serious side effects of Mahacef-Plus 100 Tablet?

Some serious side effects of this medicine include persistent vomiting, kidney damage, allergy, diarrhea, and severe gastrointestinal infections. Always consult your child’s doctor for help in such a situation.

Q. Can other medicines be given at the same time as Mahacef-Plus 100 Tablet?

Mahacef-Plus 100 Tablet can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Mahacef-Plus 100 Tablet. Also, check with your child’s doctor before giving any medicine to your child.

Q. Can I get my child vaccinated while on treatment with Mahacef-Plus 100 Tablet?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

Q. Can Mahacef-Plus 100 Tablet impact my child’s digestion?

Children often have a sensitive stomach and develop a stomach upset while taking antibiotics. When antibiotics are given, the medicine may kill off the good bacteria along with the bad ones, increasing the risk of developing other infections. In case your child is having diarrhea while on Mahacef-Plus 100 Tablet, do not stop the medicine course. Instead, call your child’s doctor to ask about the next steps. In some cases, the doctor may alter the dose.

Q. Can Mahacef-Plus 100 Tablet lead to bacterial resistance in my child?

Yes, the infection-causing bacteria can become resistant to Mahacef-Plus 100 Tablet because of irregular dosing, unrequired repeated use, and misuse of Mahacef-Plus 100 Tablet can lead to resistance. Resistant bacteria are no longer killed by the antibiotics and may lead to reinfection.

Q. What should I tell the doctor before giving Mahacef-Plus 100 Tablet to my child?

Inform the doctor if your child is suffering from heart disease, genetic disorders involving blood vessels, seizures, psychiatric disorders, diabetes, photoallergy (allergy from sunlight), neuromuscular disorders, or rheumatoid arthritis. This is because there is a possibility that Mahacef-Plus 100 Tablet may aggravate these conditions and result in complications.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Tiwaskar M. Cefixime-ofloxacin Combination in the Management of Uncomplicated Typhoid Fever in the Indian Community Setting. J Assoc Physicians India. 2019;67(3):75-80. [Accessed 29 Jan. 2021] (online) Available from:External Link
  2. Healthy Children. Antibiotic Prescriptions for Children: 10 Common Questions Answered. [Accessed 29 Jan. 2021] (online) Available from:External Link
  3. Mayo Clinic: Drugs and Supplements. Cefixime (Oral Route). [Accessed 29 Jan. 2021] (online) Available from:External Link
  4. Nationwide Children’s. Cefixime oral suspension. [Accessed 29 Jan. 2021] (online) Available from:External Link
  5. University of Michigan: C.S. Mott Children’s Hospital. Ofloxacin. [Accessed 29 Jan. 2021] (online) Available from:External Link

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Country of origin: India
Expires on or after: July, 2025

A licensed vendor partner from your nearest location will deliver Mahacef-Plus 100 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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