Magnesium Sulphate 0.25% Injection

Magnesium Sulphate (25% w/v)

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Magnesium Sulphate 0.25% Injection is a medicine used in the treatment of decreased magnesium levels in blood. It is also used for treatment of seizures in pregnant women who have high blood pressure. It widens the blood vessels in the brain and improves the blood supply to the nerve cells.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 28 Jul 2026 | 01:04 AM (IST)

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General Information

Contains

Magnesium Sulphate (25% w/v)

Marketer

Hindustan Antibiotics Ltd

Storage

Store below 30°C

The content is shown in English

Magnesium Sulphate 0.25% Injection image

Product introduction

Magnesium Sulphate 0.25% Injection is generally administered by a healthcare professional in a hospital or clinical setting. You should not self-administer this medicine at home. Using of Magnesium Sulphate 0.25% Injection may cause redness, pain, and swelling at the site of injection. If these side effects persist or worsen, inform your doctor.

Uses of Magnesium Sulphate Injection

Seizures in pregnant women with high blood pressure
Decreased magnesium levels in blood

Benefits of Magnesium Sulphate Injection

Seizures in pregnant women with high blood pressure
Magnesium Sulphate 0.25% Injection is mostly used with other medicines to prevent and control seizures (fits) in pregnant women with high blood pressure. It can help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. This medicine may take several weeks or months to work effectively as the dose is adjusted. Carefully follow all instructions and never take more tablets than your doctor tells you to. It needs to be taken regularly as prescribed to be most effective.

Decreased magnesium levels in blood
Magnesium Sulphate 0.25% Injection is also used to improve the level of magnesium in blood which is a very essential nutrient for carrying out various functions of our body. It has many benefits such as maintaining bone density and strength, calming the brain, relieving anxiety, and making you sleep better. It also helps to control blood sugar in people with diabetes and may lower the risk of developing diabetes. Additionally, it decreases abnormal heart rhythms and reduces premenstrual syndrome (PMS) symptoms such as abnormal cramps, mood swings, nausea, tiredness, or restlessness. Overall, it helps to improve your quality of life.

Side effects of Magnesium Sulphate Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Magnesium Sulphate

Injection site reactions (pain, swelling, redness)

How to use Magnesium Sulphate Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Magnesium Sulphate Injection works

Magnesium Sulphate 0.25% Injection controls seizures and high blood pressure in pregnant women by widening the blood vessels in the brain and improving the blood supply to the nerve cells. It also treats low levels of magnesium in the blood.

Quick tips

Magnesium Sulphate 0.25% Injection is given to improve the level of magnesium in the blood and to prevent seizures in pregnant women with high blood pressure.
If you are taking any antibiotics, take it either 2 hours prior or 4 hours after taking Magnesium Sulphate 0.25% Injection.
Inform your doctor if you have any bleeding disorder, heart blockage, kidney problems, or breathing problems.
You will be asked to get your blood and urine test done while taking Magnesium Sulphate 0.25% Injection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Magnesium Sulphate 0.25% Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Magnesium Sulphate 0.25% Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Magnesium Sulphate 0.25% Injection can cause fetal abnormalities when administered beyond 5-7 days to pregnant women.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

CONSULT YOUR DOCTOR

It is not known whether Magnesium Sulphate 0.25% Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Magnesium Sulphate 0.25% Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Magnesium Sulphate 0.25% Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

What is Magnesium Sulphate 0.25% Injection used for?

Magnesium Sulphate 0.25% Injection is used to treat serious conditions such as convulsions (seizures) caused by pre-eclampsia, and eclampsia during pregnancy, and to control seizures associated with acute nephritis in children. It is also used to treat low magnesium levels (hypomagnesemia), uterine tetany (prolonged, strong, and sustained contraction of the uterus), and premature labor.

Who should not use Magnesium Sulphate 0.25% Injection?

Magnesium Sulphate 0.25% Injection should not be given to patients with heart block, severe heart conditions, or those with serious kidney impairment. It should also be avoided in pregnant women in the two hours before delivery.

Are there any serious side effects of Magnesium Sulphate 0.25% Injection I should watch out for?

Yes, Magnesium Sulphate 0.25% Injection can cause serious side effects such as low blood pressure, respiratory depression, and cardiac arrest. If you experience extreme weakness, difficulty breathing, or severe changes in your heart rate, contact your doctor immediately.

How does Magnesium Sulphate 0.25% Injection work to control seizures?

Magnesium Sulphate 0.25% Injection works by blocking neuromuscular transmission and reducing the amount of acetylcholine released by nerves, which helps prevent and control seizures. It also has a calming effect on the central nervous system.

Can I use Magnesium Sulphate 0.25% Injection if I have kidney problems?

Magnesium Sulphate 0.25% Injection should be used cautiously in people with kidney problems, as the medicine is excreted by the kidneys. If you have renal impairment, your doctor may adjust the dosage or closely monitor your kidney function while you are using this medication.

Fact Box

Chemical Class

Alkaline Earth Metal Sulfate

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Inorganic Compounds

Related lab tests

Calcium

Magnesium

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 833.
Magnesium Sulphate. Lake Forest, Illinois: Hospira, Inc.; 2013. [Accessed 05 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 05 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hindustan Antibiotics Ltd
Address: Hindustan Antibiotics Limited, Pimpri, Pune - 411018

Vendor Details

Country of origin: India

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Magnesium Sulphate 0.25% Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Magnesium Sulphate Injection

Benefits of Magnesium Sulphate Injection

Side effects of Magnesium Sulphate Injection

How to use Magnesium Sulphate Injection

How Magnesium Sulphate Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Magnesium Sulphate 0.25% Injection used for?

Who should not use Magnesium Sulphate 0.25% Injection?

Are there any serious side effects of Magnesium Sulphate 0.25% Injection I should watch out for?

How does Magnesium Sulphate 0.25% Injection work to control seizures?

Can I use Magnesium Sulphate 0.25% Injection if I have kidney problems?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Calcium

Magnesium

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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