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Lypex SB Injection is a combination medicine. It is prescribed to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 23 Sep 2025 | 05:12 PM (IST)
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General Information

Contains

Cefoperazone (1000mg)+ Sulbactam (500mg)

Marketer

Hetero Drugs Ltd

Storage

Store below 30°C
The content is shown in English
Lypex SB Injection image
Lypex SB Injection image

Product introduction

Lypex SB Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Lypex SB Injection

Benefits of Lypex SB Injection

Treatment of Bacterial infections
Lypex SB Injection contains two different medicines, Cefoperazone and Sulbactum, that work together to kill the bacteria that cause infections. Cefoperazone works by stopping the growth of bacteria. Sulbactam reduces resistance and enhances the activity of Cefoperazone against bacteria.

Lypex SB Injection can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Lypex SB Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lypex SB
  • Decreased white blood cell count (neutrophils)
  • Decreased white blood cell count (lymphocytes)
  • Decreased hemoglobin
  • Decreased hematocrit level
  • Low blood platelets
  • Coagulation disorder
  • Increased white blood cell count (eosinophils)
  • Diarrhea
  • Nausea
  • Increased alanine aminotransferase
  • Increased aspartate aminotransferase
  • Increased alkaline phosphatase level in blood
  • Vomiting
  • Increased bilirubin in the blood

How to use Lypex SB Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lypex SB Injection works

Lypex SB Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

All substitutes for Lypex SB Injection

For information purposes only. Consult a doctor before taking any medicine.

Zostum 1.5gm Injection

by Zuventus Healthcare Ltd
₹514.3/injection
71% costlier
<h3 class=bodySemiBold>Zostum 1.5gm Injection</h3>

Sulbacef 1000mg/500mg Injection

by Zydus Healthcare Limited
₹350.63/injection
17% costlier
<h3 class=bodySemiBold>Sulbacef 1000mg/500mg Injection</h3>

Lactagard 1500 Injection

by Ipca Laboratories Ltd
₹323.7/injection
8% costlier
<h3 class=bodySemiBold>Lactagard 1500 Injection</h3>

Zonamax ES 1000mg/500mg Injection

by Macleods Pharmaceuticals Pvt Ltd
₹275.6/injection
8% cheaper
<h3 class=bodySemiBold>Zonamax ES 1000mg/500mg Injection</h3>

Efatum 1000 mg/500 mg Injection

by BestoChem Formulations India Ltd
₹195.05/injection
35% cheaper
<h3 class=bodySemiBold>Efatum 1000 mg/500 mg Injection</h3>

Quick tips

  • You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance. 
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Lypex SB Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Stop taking Lypex SB Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Safety advice

Alcohol

Alcohol

UNSAFE
Consuming alcohol while taking Lypex SB Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Lypex SB Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Lypex SB Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Lypex SB Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Lypex SB Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Lypex SB Injection in patients with liver disease. Please consult your doctor.

Frequently asked questions

Lypex SB Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.
Usually, Lypex SB Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

  1. Sterile cefoperazone. New York, New York, Pfizer Inc.; 2015. [Accessed 09 Apr. 2019] (online) Available from:
  2. PubChem. Sulbactam Sodium. [Accessed 09 Apr. 2019] (online) Available from:
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User feedback

Bacterial infections
100%
Poor
67%
Average
33%
Headache
100%
Empty stomach
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hetero Drugs Ltd
Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lypex SB Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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