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food interaction for LUPIHIST

alcohol interaction for LUPIHIST

pregnancy interaction for LUPIHIST

lactation interaction for LUPIHIST

There is no data available. Please consult doctor before consuming the drug.
Lupihist syrup may cause excessive drowsiness and calmness with alcohol.
Lupihist syrup is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
Lupihist syrup is probably unsafe to use during breastfeeding. Please consult your doctor.


Diphenhydramine(15 mg)


Diphenhydramine is used in the treatment of allergic disorders and motion sickness

How it works

Diphenhydramine blocks the action of certain chemical messengers that are responsible for inflammation, congestion, itching, and other allergic reactions.

Common side effects

Nausea, Nervousness, Palpitations, Abnormal sensation in skin, Blurred vision, Confusion, Convulsion, Difficulty in paying attention, Dizziness, Drowsiness, Dry mouth, Shortness of breath, Difficulty in urination, Eye swelling, Lip swelling, Fatigue, Headache, Hypersensitivity reaction, Inability to empty the urinary bladder, Increased energy, Muscle twitching, Restlessness, Ringing in ear, Sedation, Tachycardia, Thickened respiratory tract secretions, Unsteadiness, Vomiting
Sodium Citrate(80 mg)


Sodium Citrate is used in short term fluid replacement after trauma, dehydration and irrigation solution for eye/nose

How it works

Sodium citrate is a salt and belongs to class of medications called as urinary alkalinizers. It neutralizes excess acid in the blood and urine thereby relieving the associated symptoms.

Common side effects

Volume overload
Ammonium Chloride(150 mg)


Ammonium Chloride is used in the treatment of cough with mucus

How it works

Ammonium Chloride works by decreasing the stickiness of airway secretions and help their removal from the airways.

Common side effects

Facial swelling, Allergic reaction, Difficulty in swallowing, Sickness, Nausea, Stomach pain, Shortness of breath, Throat disorder
Pseudoephedrine(30 mg)


Pseudoephedrine is used in the treatment of rhinitis (common cold)

How it works

Pseudoephedrine belongs to the class of medications known as decongestants. Pseudoephedrine works by relaxing the smooth muscles in the nasal cavity which decreases excess secretion of mucous in nasal cavity and sinuses (air cavities) thereby relieving congestion.

Common side effects

Nausea, Headache, Vomiting, Weakness, Restlessness


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Expert advice FOR LUPIHIST

  • Do not drive or operate machinery after taking diphenhydramine as it may cause dizziness or drowziness.
  • Avoid alcohol intake.
  • Drink plenty of fluids to prevent dehydration.
  • It is best to take this drug at bedtime as it makes you sleepy or drowsy.
Do not start or continue the diphenhydramine tablets:
  • If you are allergic (hypersensitive) to diphenhydramine or any of the other ingredients of diphenhydramine tablet.
  • If you have asthma, chronic obstructive pulmonary disorder (COPD) or other breathing disorder, narrow angle glaucoma, stomach ulcer or obstruction of the gut or bladder, porphyria, thyroid disorder, heart disease, prostrate problem.
  • If you have an intolerance to some sugars like lactose.
  • If you are pregnant or breastfeeding.
  • If you have prostate problems.
Doctor’s advice should be considered before taking diphenhydramine tablets in case of any following disease conditions such as:
  • Liver problems
  • Long-term lung problems or difficulty breathing due to bronchitis.
  • Glaucoma
  • Difficulty passing urine
  • Fits
  • Myasthenia gravis
  • Tinnitus
  • Rare hereditary problems of galactose intolerance, the Lap lactase deficiency or glucose-galactose malabsorption.

Frequently asked questions FOR LUPIHIST


Q. Is diphenhydramine a blood thinner/narcotic/water soluble?
No, it is an antihistaminic drug and not a blood thinner or narcotic

Q. Is diphenhydramine Hcl the same as Benadryl?
Benadryl is a trade name of product containing the drug diphenhydramine

Q. Is diphenhydramine hydrochloride/Benadryl safe?
It is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Is Benadryl safe for infants?
No, it should not be given to infants. Always follow doctor's advice regarding its use

Q. Is Benadryl an expectorant/antibiotic?
Benadryl is an expectorant as guaifenesin is one of its components. And it is not an antibiotic

Q. Is Benadryl banned in India?
No, it is available in India

Q. Is Benadryl effective?
It is effective at prescribed doses for the prescribed duration and disease condition as advised by your doctor

Q. Can you take diphenhydramine/ Benadryl for anxiety/cold/hives/bug bites/sleep?
Diphenhydramine tablet is used for the relief of short term sleeplessness. It can be used for cold and treatment of hives. Always follow doctor's advice regarding its use

Q. Can I take Benadryl for a rash/dry cough/cold/eczema/ sinus infection/yeast infection/headaches/sinus/motion sickness/ skin rash/itchy skin?
Benadryl is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. It is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson's disease. But, it is not used for eczema, sinus infection, and yeast infection. Always follow doctor's advice regarding its use

Q. Can I take diphenhydramine with hydrocodone/dextromethorphan and guaifenesin/ acetaminophen/phenylephrine/tramadol/Zoloft/ doxylamine succinate/prednisone/ citalopram/Advil?
Yes, but taking other medicines may alter the effects of diphenhydramine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required

Q. Can I take Benadryl with Zyrtec/Mucinex/Sudafed/ Tamiflu/ amoxicillin/Xanax/Advil/ azithromycin/Norco/robitussin?
Yes, but taking other medicines may alter the effects of Benadryl. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required

Q. Does diphenhydramine make you sleepy/drowsy?
Yes, it makes you sleepy/drowsy. Always follow doctor's advice regarding its use

Q. Does diphenhydramine cause Alzheimer's/depression/constipation/dementia/increase blood pressure?
Diphenhydramine causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects

Q. Does diphenhydramine potentiate opiates?
No it does not potentiate opiates

Q. Does Benadryl make you sleepy/high/ raise blood pressure/weight gain?
Benadryl causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects.

Sodium Citrate

Q. Is sodium citrate ionic, covalent, or dissolve in water?
Sodium citrate is an ionic compound and dissolves in water. It does not contain covalent bonds

Q. Is sodium citrate a preservative, vegan or natural compound?
Yes, sodium citrate is a vegan compound used as a preservative

Q. Can I take sodium citrate with antibiotics?
No, avoid taking any two medications together and keep a gap of at least 1 hour between two drugs

Q. Does sodium citrate cause diarrhea?
Yes, long term use of sodium citrate can cause diarrhea

Q. Does sodium citrate cure cystitis and cancer?
Sodium citrate is used to treat cystitis (inflammation of the urinary bladder) in women. It is not known to cause cancer

Q. Does sodium citrate contain gluten?
No, sodium citrate does not contain gluten

Q. Does sodium citrate bind calcium and have iodine in its structure?
No, sodium citrate does not contain iodine but it binds to the calcium in the blood and reduces blood clotting

Q. Is sodium citrate the same as citric acid?
Sodium citrate is an acid salt of citric acid

Q. Is sodium citrate safe?
Sodium citrate is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Ammonium Chloride

Q. How does ammonium chloride work?
Ammonium chloride is used as an expectorant (helps in bringing mucus out of the lungs) thus helping in curing cough. Ammonium chloride is used to maintain the acid-base balance in the body and thus is used to treat patients with hypochloremia and metabolic alkalosis

Q. Is ammonium chloride safe/ dangerous?
Anmmonium chloride is safe when taken for an indication and at a dose strictly instructed by your doctor.


Q. Can I take pseudoephedrine for allergies?
Pseudoephedrine does give symptomatic relief from seasonal allergic conditions such as runny nose and nasal decongestion.

Q. Can I take pseudoephedrine with ibuprofen?
Yes. Ibuprofen may relieve fever experienced during cold.



Content on this page was last updated on 12 January, 2017, by Dr. Varun Gupta (MD Pharmacology)