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Composition for LUPIFLEX

Ketoprofen(100 mg),Thiocolchicoside(8 mg)

food interaction for LUPIFLEX

alcohol interaction for LUPIFLEX

pregnancy interaction for LUPIFLEX

lactation interaction for LUPIFLEX

There is no data available. Please consult doctor before consuming the drug.
Taking Ketoprofen with alcohol increases the risk of stomach bleeding.
Lupiflex 100 mg/8 mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Lupiflex 100 mg/8 mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Ketoprofen(100 mg)


Ketoprofen is used in the management of inflammation and pain due to any arthritis including rheumatoid arthritis (inflammatory disorder that typically affects the small joints in hands and feet), osteoarthritis (damage to the cushioning cartilage between the joints), ankylosing spondylitis (pain due to inflammation in spine or backbone), and acute gout (painful, red, swollen joints due to deposition of uric acid in the joints). It is also used in painful menstruation (dysmenorrhea) and for control of pain and inflammation following injuries that affect bones and muscles (orthopedic) surgery.

How it works

Ketoprofen is a pain killer medication belongs to group of medicines called nonselective cyclooxygenase inhibitors (traditional non-steroidal anti-inflammatory drug [NSAID]). It inhibits the synthesis of chemicals like prostaglandin and thromboxane that results in the reduction of fever, formation of blood clots, pain and inflammation.

Common side effects

Nausea, Heartburn, Indigestion, Stomach pain, Vomiting
Thiocolchicoside(8 mg)


Thiocolchicoside is used (as an additive treatment) for relieving painful stiffness or constriction in various diseases of the muscles, nerves, spine and the joints.

How it works

Thiocolchicoside belongs to group of medicines called muscle relaxant. It is semi-synthetic derivative of naturally occurring compound colchicoside. It acts against chemical called gamma amino-butyric acid (GABA). It reduces the swelling (anti-inflammatory) and pain (analgesic), and relaxes the muscles.

Common side effects

Abdominal cramp, Abdominal bloating, Abdominal pain, Diarrhoea, Dizziness, Fatigue, Headache, Influenza like symptoms, Nausea, Weakness

Common Dosage

Patients taking this medicines

  • 64%
    Two Times A Day
  • 18%
    Three Times A Day
  • 18%
    One Time A Day


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Top General Physicians

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Expert advice for LUPIFLEX

  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Do not drive or operate any machinery because you may feel sleepy or dizzy while being treated with ketoprofen.
  • Do not consume alcohol while taking ketoprofen as it may cause serious side effects.
  • Caution should be taken when giving ketoprofen to children younger than 18 years or elderly 65 years of age or older.

Frequently asked questions for LUPIFLEX


Q. Is ketoprofen safe?
Ketoprofen is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is ketoprofen a blood thinner?
No, ketoprofen is not a blood thinner.
Q. Is ketoprofen a controlled substance?
No, ketoprofen is not a controlled substance.
Q. Is ketoprofen the same as ibuprofen?
Both ketoprofen and ibuprofen belongs to the same class, i.e non-steroidal anti-inflammatory drug (NSAID), but their effect may vary upon individual condition or response.
Q. Can I take ketoprofen with Aspirin (acetylsalicylic acid), Tylenol (acetaminophen), Vicodin (acetaminophen and hydrocodone), hydrocodone, ibuprofen, paracetamol, or tramadol?
Ibuprofen should not be given with ketoprofen. It is not reported to interact with Aspirin, Tylenol, Vicodin, hydrocodone, paracetamol, or tramadol. Please follow the advice of the doctor regarding their simultaneous use.
Q. Does ketoprofen contain aspirin, ibuprofen, or ketamine?
No, ketoprofen does not contain aspirin, ibuprofen, or ketamine.
Q. Does ketoprofen cause drowsiness?
Yes, ketoprofen may cause drowsiness. Please consult your doctor before taking the drug.


Q. Is thiocolchicoside a steroid?
No, thiocolchicoside is not a steroid. It is a semi-synthetic muscle relaxant.
Q. Thiocolchicoside is derived from which plant?
Thiocolchicoside is a semi-synthetic derivative of naturally occurring compound colchicoside from the plant Gloriosa superba.
Q. What is thiocolchicoside and aceclofenac?
Thiocolchicoside is used as combination with aceclofenac to treat painful muscular contraction (spasm).
Q. Is thiocolchicoside safe?
Thiocolchicoside is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.


Content on this page was last updated on 21 January, 2016, by Dr. Varun Gupta (MD Pharmacology)