Losfirst H Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 13 Nov 2025 | 02:35 PM (IST)

Losfirst H Tablet is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.

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General Information

Contains

Losartan (50mg)+ Hydrochlorothiazide (12.5mg)

Marketer

Zyphar's Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

You can take Losfirst H Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.

The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhea, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of hydrochlorothiazide and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.

This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.

Uses of Losfirst H Tablet

Treatment of Hypertension (high blood pressure)

Benefits of Losfirst H Tablet

Treatment of Hypertension (high blood pressure)
Losfirst H Tablet is a combination of two medicines namely Losartan and Hydrochlorothiazide. It is generally used when one medicine alone is not controlling your blood pressure effectively. Losartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Hydrochlorothiazide is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Side effects of Losfirst H Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Losfirst H

Increased blood uric acid
Nausea
Taste change
Upset stomach
Headache
Dizziness
Weakness
Decreased blood pressure
Increased blood lipid level
Glucose intolerance
Electrolyte imbalance

How to use Losfirst H Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Losfirst H Tablet may be taken with or without food.

How Losfirst H Tablet works

Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

All substitutes for Losfirst H Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Losfirst H Tablet for the treatment of high blood pressure.
It can be taken with or without food.
Losfirst H Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Use of Losfirst H Tablet during pregnancy or breastfeeding is unsafe.
It may also decrease the risk of stroke and heart attacks.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Losfirst H Tablet

Pregnancy

CONSULT YOUR DOCTOR

Losfirst H Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Losfirst H Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Losfirst H Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Losfirst H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Losfirst H Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Losfirst H Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Are there any special instructions regarding storage and disposal of this medicine?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I feel dizzy after taking Losfirst H Tablet?

Yes, the use of Losfirst H Tablet can make you feel dizzy. This may occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Can I use Losfirst H Tablet in pregnancy?

No, Losfirst H Tablet should be avoided in pregnancy. Its use can cause injury and death to the baby. If you conceive while using Losfirst H Tablet, stop using it and contact your doctor immediately. Your doctor will recommend you other ways to lower the blood pressure.

What are some lifestyle changes to make while using Losfirst H Tablet?

Making lifestyle changes can boost your health while taking Losfirst H Tablet. Avoid smoking, as smoking increases your risk of having heart attack and stroke. If you are overweight or obese, try to lose weight. You should maintain a healthy diet by including fruits and vegetables in your meals. Regular exercise can make your heart strong and reduce the risk of heart attack.

Can I stop taking Losfirst H Tablet if I feel well?

No, keep using Losfirst H Tablet as advised by your doctor, even if you feel well. Stopping Losfirst H Tablet suddenly may lead to serious complications such as heart attack and stroke.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Related lab tests

Kidney Function Test

References

User feedback

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Hypertension (high blood pressure)

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zyphar's Pharmaceuticals Pvt Ltd
Address: 102/103, Park Plaza, Opp. Kamla Nehru Park, Off. Bhandarkar Road, Pune - 411004, Maharashtra (India)

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Losfirst H Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Losfirst H Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Losfirst H Tablet

Benefits of Losfirst H Tablet

Side effects of Losfirst H Tablet

How to use Losfirst H Tablet

How Losfirst H Tablet works

All substitutes for Losfirst H Tablet

Cosart-H Tablet

Losar-H Tablet

Repace H Tablet

Losakind-H Tablet

Covance-D Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Are there any special instructions regarding storage and disposal of this medicine?

Can I feel dizzy after taking Losfirst H Tablet?

Can I use Losfirst H Tablet in pregnancy?

What are some lifestyle changes to make while using Losfirst H Tablet?

Can I stop taking Losfirst H Tablet if I feel well?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Kidney Function Test

References

User feedback

What are you using Losfirst H Tablet for?

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests