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Ledoben Tablet is a prescription medicine used in the treatment of Parkinson's disease. It helps to reduce excessive shaking by slowing down the body movements. It works by increasing the amount of chemical messenger that is needed to control abnormal movements.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 26 Jul 2026 | 01:02 AM (IST)
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Ledoben Tablet image
Ledoben Tablet image
Ledoben Tablet image
Ledoben Tablet image

Product introduction

Ledoben Tablet can be taken with or without food but it is better to avoid high protein diet and dairy products while taking this medicine. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better. Do not stop taking medicine until told by your doctor as it can cause harmful effects.

This medicine may cause side effects like nausea, vomiting, dryness in mouth, constipation, and headache. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it's better to rise slowly if you have been sitting or lying down. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Ledoben Tablet

Benefits of Ledoben Tablet

Parkinson's disease
Ledoben Tablet is a medicine that helps relieve symptoms of Parkinson's disease such as tremors, muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Side effects of Ledoben Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ledoben
  • Nausea
  • Vomiting
  • Dryness in mouth
  • Constipation
  • Anxiety
  • Dizziness
  • Headache
  • Abnormal dreams
  • Insomnia (difficulty in sleeping)
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Abnormality of voluntary movements

How to use Ledoben Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ledoben Tablet may be taken with or without food.
Avoid Ledoben Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How Ledoben Tablet works

Ledoben Tablet is a combination of two medicines: Levodopa and Benserazide which treats Parkinsonism. Levodopa is a dopamine precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Benserazide is a peripheral decarboxylase inhibitor which prevents breakdown of levodopa allowing it to enter the brain and increase dopamine levels.

Quick tips

  • You have been prescribed Ledoben Tablet to treat your symptoms of Parkinson's disease.
  • It can be taken with or without food or as directed by your doctor.
  • Reduce/avoid a high-protein diet (e.g. meat, poultry, and dairy products) while you are taking the medicine as it can reduce the amount of medication absorbed by your body.
  • Be cautious while driving or doing anything that requires concentration as Ledoben Tablet can make you very sleepy.
  • When you start the medication, get out of bed slowly, as the medication may cause dizziness, lightheadedness or fainting.
  • Do not stop taking the medication without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating, and confusion.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Ledoben Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ledoben Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Ledoben Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Ledoben Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Ledoben Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
No dose adjustment of Ledoben Tablet is required in mild or moderate liver disease.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Ledoben Tablet in patients with liver disease.
All

Frequently asked questions

Ledoben Tablet (mainly levodopa) can make you feel very sleepy. This can happen just after taking the medicine, even during the day. If you experience lack of focus because of sleepiness you must not drive or use machinery. Consult your doctor to know what particular activities you can be involved in, while taking this medicine.
The effects of Ledoben Tablet on human bone during prolonged administration is not known. It is not to be given in patients less than 25 years of age since the skeletal development is incomplete. Also, it should be used with caution in patients with osteomalacia and osteoporosis.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Levodopa and benserazide. Auckland, New Zealand: Roche Products; 2016. [Accessed 23 Apr. 2019] (online) Available from:
  2. Levodopa and benserazide. Segrate, Italy: Delpharm Milano S.r.l; 2024.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Peakmed Lifecare Enterprise
Address: C-123, 1st Floor, Sneh Plaza, Suvidha Comm. & Hous. Society, IOC Road, Chandkheda, Ahmedabad-382424, Gujarat

Vendor Details

Country of origin: India
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