Leadcef CV 500mg/125mg Tablet

Cefuroxime (500mg)+ Clavulanic Acid (125mg)

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Leadcef CV 500mg/125mg Tablet is a potent antibiotic that effectively treats bacterial infections of the ear, nose, throat, lungs, skin, soft tissues, bones, joints, abdomen, and urinary tract in children. It also prevents infection after surgeries and animal or human bite wounds.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 17 Jul 2026 | 01:05 AM (IST)

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General Information

Contains

Cefuroxime (500mg)+ Clavulanic Acid (125mg)

Marketer

Human Discovery Pharma & Research

Storage

Store below 30°C

The content is shown in English

Product introduction

Leadcef CV 500mg/125mg Tablet can be given either before or after meals but giving it with food improves absorption and reduces the chances of stomach upset in your child. The dose and duration depend upon the type and severity of the infection, so stick to the dose, time, and way prescribed by the doctor. If your child vomits within 30 minutes of the intake, give the same dose again but do not double dose if it is already time for the next dose.

This medicine may have some minor and temporary side effects such as vomiting, diarrhea, nausea, abdominal pain, and allergy. These episodes should start receding after a few doses. However, if these side effects persist or become bothersome for your child, report to the doctor without any delay.

Narrate your child’s complete medical history to your child’s doctor, including any previous episode of allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.

Uses of Leadcef CV Tablet

Treatment of Bacterial infections

Benefits of Leadcef CV Tablet

Treatment of Bacterial infections
Leadcef CV 500mg/125mg Tablet contains two different medicines, Cefuroxime and Clavulanic Acid, that work together to kill the bacteria that cause infections. Cefuroxime works by stopping the growth of bacteria. Clavulanic Acid reduces resistance and enhances the activity of Cefuroxime against bacteria.

This combination medicine can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Leadcef CV Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Leadcef CV

Nausea
Vomiting
Diarrhea
Abdominal pain
Allergy

How to use Leadcef CV Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leadcef CV 500mg/125mg Tablet should be taken with or after food.

How Leadcef CV Tablet works

Leadcef CV 500mg/125mg Tablet is a combination of two medicines: Cefuroxime and Clavulanic Acid. Cefuroxime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Clavulanic Acid is a beta-lactamase inhibitor which blocks the action of enzymes produced by bacteria to inactivate Cefuroxime. Addition of Clavulanic Acid reduces resistance and enhances the activity of Cefuroxime against bacteria.

All substitutes for Leadcef CV 500mg/125mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
Conditions like common cold and flu are caused by viruses. This medicine is not to be taken in such cases.
Only give Leadcef CV 500mg/125mg Tablet to your child for their current infection. Never save medicine for future illnesses.
Discontinue giving Leadcef CV 500mg/125mg Tablet and consult the doctor immediately in case your child develops an itchy rash, facial swelling, or breathing difficulties while taking this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Leadcef CV 500mg/125mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Leadcef CV 500mg/125mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

NOT RELEVANT

Not relevant, as Leadcef CV 500mg/125mg Tablet is intended for use in hospitalized patients.

Kidney

CAUTION

Leadcef CV 500mg/125mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Leadcef CV 500mg/125mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.
However, consult with your child’s doctor before giving this medicine to your child in case of a severe form of liver disease.

Frequently asked questions

My child is underweight and is not growing as per his age. Is it safe to give Leadcef CV 500mg/125mg Tablet?

Use Leadcef CV 500mg/125mg Tablet with caution as it may be associated with blood clotting problems especially in children who are underweight and not growing adequately. This risk is further increased if the child has underlying liver and kidney disease. Consult your child’s doctor in such cases.

My child is suffering from a seizure disorder. Can I give Leadcef CV 500mg/125mg Tablet to my child?

Leadcef CV 500mg/125mg Tablet may cause seizure activity, particularly in children who have kidney disease. So, Leadcef CV 500mg/125mg Tablet should be used with caution in children with a history of seizure disorder. If seizures occur, discontinue Leadcef CV 500mg/125mg Tablet and visit your child’s doctor right away.

What if I give too much of Leadcef CV 500mg/125mg Tablet by mistake?

An extra dose of Leadcef CV 500mg/125mg Tablet is unlikely to harm. However, if you think you have given too much of Leadcef CV 500mg/125mg Tablet to your child, immediately speak to a doctor. Overdose may cause unwanted side effects and may even worsen your child’s condition.

For how long do I need to give Leadcef CV 500mg/125mg Tablet to my child?

Give Leadcef CV 500mg/125mg Tablet for as long as advised by the doctor. Usually, it takes 3 to 5 days for the infection to start improving. However, you must still finish the full course of the medicine and never stop it abruptly by yourself as that may worsen your child’s condition or cause infection recurrence.

Are there any possible serious side effects of Leadcef CV 500mg/125mg Tablet?

Some serious side effects of this medicine include persistent vomiting, kidney damage, allergy, diarrhea, and severe gastrointestinal infections. Always consult your child’s doctor for help in such a situation.

Can other medicines be given at the same time as Leadcef CV 500mg/125mg Tablet?

Leadcef CV 500mg/125mg Tablet can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Leadcef CV 500mg/125mg Tablet. Also, check with your child’s doctor before giving any medicine to your child.

Can I get my child vaccinated while on treatment with Leadcef CV 500mg/125mg Tablet ?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

Does a common cold caused by viruses always result in a secondary bacterial infection? When to start an antibiotic to prevent infection?

In most cases, bacterial infections do not follow viral infections. Using antibiotics to treat viral infections may instead lead to side effects without benefiting your child's health. Hence, you must give antibiotics to your child only after consulting with your child’s doctor.

Can Leadcef CV 500mg/125mg Tablet impact my child’s digestion?

Antibiotics kill the infection-causing bacteria, but while doing this they may affect the good bacteria present in the gastrointestinal tract. As a result, your child may develop diarrhea or some other infections as well. Moreover, children have a more sensitive stomach than adults, so the likelihood of developing a stomach upset is more. In case your child is having diarrhea while on Leadcef CV 500mg/125mg Tablet, do not stop the medicine course. Instead, call your child’s doctor to ask about the next steps. In some cases, the doctor may alter the dose.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Human Discovery Pharma & Research
Address: 2nd Floor, Plot No- 62, near Industrial Area , Phase 2, Harmilap Nagar, Phase 1, Baltana, Industrial Area Phase 2, Panchkula, Zirakpur, Haryana 134112

Vendor Details

Country of origin: India

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Why we need a prescription?

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Anti Infectives

Cephalosporins

Leadcef CV 500mg/125mg Tablet

Leadcef CV 500mg/125mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Leadcef CV Tablet

Benefits of Leadcef CV Tablet

Side effects of Leadcef CV Tablet

How to use Leadcef CV Tablet

How Leadcef CV Tablet works

All substitutes for Leadcef CV 500mg/125mg Tablet

Cefaprime-CV Tablet

Venroxim CV 500mg/125mg Tablet

Ceroxitum CV 500mg/125mg Tablet

Cefakind-CV 500 Tablet

Forcef-CV 500 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

My child is underweight and is not growing as per his age. Is it safe to give Leadcef CV 500mg/125mg Tablet?

My child is suffering from a seizure disorder. Can I give Leadcef CV 500mg/125mg Tablet to my child?

What if I give too much of Leadcef CV 500mg/125mg Tablet by mistake?

For how long do I need to give Leadcef CV 500mg/125mg Tablet to my child?

Are there any possible serious side effects of Leadcef CV 500mg/125mg Tablet?

Can other medicines be given at the same time as Leadcef CV 500mg/125mg Tablet?

Can I get my child vaccinated while on treatment with Leadcef CV 500mg/125mg Tablet ?

Does a common cold caused by viruses always result in a secondary bacterial infection? When to start an antibiotic to prevent infection?

Can Leadcef CV 500mg/125mg Tablet impact my child’s digestion?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests