Kyzific 40mg Tablet

Asciminib (40mg)

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Kyzific 40mg Tablet is a prescription medication used to treat adults with a type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It targets and inhibits specific proteins that promote cancer cell growth and helps manage and control the progression of CML.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 20 Apr 2026 | 12:03 PM (IST)

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General Information

Contains

Asciminib (40mg)

Marketer

Novartis India Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Kyzific 40mg Tablet may be taken with or without food. Take it exactly as prescribed by your doctor. Try to take your medication at the same time every day for maximum benefits. Make sure to follow your doctor’s instructions regarding blood tests and other evaluations to monitor your response to the treatment.

Common side effects include nausea, diarrhea, headache, fatigue, and muscle pain. If you experience these symptoms, talk to your doctor. They may be able to offer strategies to manage these side effects and ensure they do not interfere with your treatment. Drinking plenty of water, eating small and frequent meals, and getting adequate rest can help alleviate some of these symptoms.

While on treatment with Kyzific 40mg Tablet avoid grapefruit and grapefruit juice, as they can interfere with the effectiveness of the medicine. Let your doctor know about all other medications, supplements, or herbal products you are taking, as this medicine can interact with other substances. Be cautious about activities that may increase your risk of bleeding or injury, as Kyzific 40mg Tablet can sometimes affect blood clotting. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their doctor to make sure it is safe for them.

Uses of Kyzific Tablet

Treatment of Blood cancer (Chronic myeloid leukaemia)

Benefits of Kyzific Tablet

Treatment of Blood cancer (Chronic myeloid leukaemia)
Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) is a type of blood cancer where there is an abnormal chromosome called the Philadelphia chromosome. Ph+ CML is a specific form of CML identified by the presence of this Philadelphia chromosome.

Kyzific 40mg Tablet works by specifically targeting the abnormal protein that causes cancer cell growth, helping to control the disease. This targeted approach not only improves the management of CML but also minimizes damage to healthy cells, leading to potentially fewer side effects compared to traditional treatments. This helps improve the patient's overall quality of life and treatment outcomes.

Side effects of Kyzific Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kyzific

Fatigue
Nausea
Rash
Diarrhea
Low blood platelets
Increased triglyceride level in blood
Decreased white blood cell count (neutrophils)
Upper respiratory tract infection
Musculoskeletal (bone, muscle or joint) pain
Decreased hemoglobin
Elevated creatine kinase
Increased alanine aminotransferase
Increased lipase in the blood
Elevated levels of serum amylase

How to use Kyzific Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kyzific 40mg Tablet may be taken with or without food.

How Kyzific Tablet works

Kyzific 40mg Tablet works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

Quick tips

Inform your doctor if you have a history of inflammation of your pancreas.
Tell your doctor if you have a history of heart problems or blood clots in blood vessels.
Inform your doctor if you are taking some other medications.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Kyzific 40mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Kyzific 40mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Kyzific 40mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Kyzific 40mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Kyzific 40mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Kyzific 40mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Frequently asked questions

What is Kyzific 40mg Tablet used for?

Kyzific 40mg Tablet is used to treat adults with a certain type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in the chronic phase.

How should I take Kyzific 40mg Tablet?

Kyzific 40mg Tablet should be taken exactly as prescribed by your healthcare provider, usually once or twice daily, with or without food. Swallow the tablets whole with water.

Are there any serious side effects I should be aware of?

Serious side effects can include cardiovascular issues, liver problems, and pancreatitis. If you experience symptoms like chest pain, yellowing of the skin or eyes, or severe abdominal pain, seek medical attention immediately.

Can I take Kyzific 40mg Tablet with other medications?

You should inform your doctor about all other medications and supplements you are taking, Kyzific 40mg Tablet can interact with other drugs, potentially affecting its effectiveness or causing side effects.

Are there any special precautions I should follow while taking Kyzific 40mg Tablet?

Avoid grapefruit and grapefruit juice, as they can interfere with Kyzific 40mg Tablet. Also, ensure regular blood tests and check-ups with your healthcare provider to monitor your response to the treatment and manage any potential side effects.

What is Kyzific 40mg Tablet used for?

Kyzific 40mg Tablet is used to treat adults with a certain type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in the chronic phase.

How should I take Kyzific 40mg Tablet?

Kyzific 40mg Tablet should be taken exactly as prescribed by your healthcare provider, usually once or twice daily, with or without food. Swallow the tablets whole with water.

Are there any serious side effects I should be aware of?

Can I take Kyzific 40mg Tablet with other medications?

Are there any special precautions I should follow while taking Kyzific 40mg Tablet?

Fact Box

Chemical Class

Aromatic anilides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Related lab tests

Bcr-Abl Gene Translocation (Qualitative)

Bcr-Abl Gene Translocation (Quantitative)

Complete Blood Count

Peripheral Smear Examination

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: Switzerland
A licensed vendor partner from your nearest location will deliver Kyzific 40mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Kyzific 40mg Tablet

Payment

Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Kyzific Tablet

Benefits of Kyzific Tablet

Side effects of Kyzific Tablet

How to use Kyzific Tablet

How Kyzific Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Kyzific 40mg Tablet used for?

How should I take Kyzific 40mg Tablet?

Are there any serious side effects I should be aware of?

Can I take Kyzific 40mg Tablet with other medications?

Are there any special precautions I should follow while taking Kyzific 40mg Tablet?

What is Kyzific 40mg Tablet used for?

How should I take Kyzific 40mg Tablet?

Are there any serious side effects I should be aware of?

Can I take Kyzific 40mg Tablet with other medications?

Are there any special precautions I should follow while taking Kyzific 40mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Related lab tests

Bcr-Abl Gene Translocation (Qualitative)

Bcr-Abl Gene Translocation (Quantitative)

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests