Author Details
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:25 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Kolzep Forte Tablet


Overview

Introduction

Kolzep Forte Tablet is a prescription medicine used in the treatment of bipolar depression. It works by increasing the level of chemical messengers in the brain which improves mood and physical symptoms of depression.

Kolzep Forte Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, vomiting, diarrhea, constipation, dry mouth, muscle rigidity, restlessness, tremor, delayed ejaculation, anorgasmia (decreased orgasm), and low sexual desire. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

Before taking Kolzep Forte Tablet, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. You should avoid alcohol while taking Kolzep Forte Tablet, as it may worsen certain side effects.

Kolzep Forte Tablet can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Kolzep Tablet

  • Bipolar depression

Side effects of Kolzep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kolzep

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Dryness in mouth
  • Weight gain
  • Sleepiness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dizziness
  • Muscle stiffness
  • Restlessness
  • Tremor
  • Delayed ejaculation
  • Anorgasmia (decreased orgasm)
  • Low sexual desire

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Weight gain
    Try to eat a healthy balanced diet without increasing your portion sizes. Avoid processed meat or poultry and seafood. Eat small, frequent meals and eat slowly. Do not snack on foods that contain a lot of calories such as crisps, cakes, biscuits and sweets. If you feel hungry between meals, eat fruits and vegetables which have low calories. Avoid reaching for a sugary drink if you feel stressed. Fasting once a week can be an effective way to lose weight. Make sure you get enough sleep. With proper diet and lifestyle changes, you might not gain any weight or may gain only a small amount. Even then if it bothers you, ask your doctor if there are any alternative medicines that do not have this side effect.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Restlessness
    This often disappears when the condition you are being treated for is managed. You could ask your doctor about changing the dose of your medicine or alternatives if it is affecting your daily life or causing you distress. Psychological treatments may be available. Some things you can do to help yourself include stopping smoking, cutting down the amount of alcohol and caffeine you drink, and doing regular exercise. You should also eat a healthy diet and find out how to get sleep if you are having trouble. Try talking to a friend or family member. Calming breathing exercises and other relaxation techniques may also help.
  • Coping with Tremor
    These symptoms can be a sign that the dose is too high for you. It may help to change your dose or take your medicine at a different time of the day. There are also exercises that can improve muscle strength, control and coordination. In terms of lifestyle, avoid caffeine (in coffee, tea and chocolate), alcohol, and ask your doctor about other techniques to help you relax and manage stress. Talk to your doctor if this bothers you. Your doctor may be able to prescribe you medicines that can help.
  • Coping with Delayed ejaculation
    Speak to your doctor as they may be able to change your medicine or offer other treatments that might help with the problem. Making healthy lifestyle changes and eating a healthy balanced diet can help. Lose weight if you are overweight. Exercise daily and try to reduce stress and anxiety. Avoid the use of alcohol, cigarettes or recreational drugs such as marijuana which can also affect sexual function. Counselling or psychotherapy can also be helpful.

How to use Kolzep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kolzep Forte Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Kolzep Tablet works

Kolzep Forte Tablet is a combination of two medicines: Fluoxetine and Olanzapine. They work by increasing the activity of certain chemicals called serotonin, norepinephrine, and dopamine in the brain. These chemicals help relieve the symptoms of bipolar depression.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Kolzep Forte Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Kolzep Forte Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Kolzep Forte Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Kolzep Forte Tablet may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Kolzep Forte Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kolzep Forte Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Kolzep Forte Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Kolzep Forte Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Kolzep Forte Tablet
₹7.7/Tablet
Olanzotic Forte 20mg/10mg Tablet
Glenmark Pharmaceuticals Ltd
₹6.25/Tablet
save 19%
Olapin Forte 20 mg/10 mg Tablet
Crescent Therapeutics Ltd
₹9.86/Tablet
28% costlier
Fostera 20 mg/10 mg Tablet
Intas Pharmaceuticals Ltd
₹11.6/Tablet
51% costlier
Olanex Plus 10 Tablet
Strides shasun Ltd
₹12.84/Tablet
67% costlier
Oleanz Forte Tablet
Sun Pharmaceutical Industries Ltd
₹15.4/Tablet
100% costlier

Quick Tips

  • You have been prescribed Kolzep Forte Tablet for the treatment of bipolar disorder with depression.
  • Take it in the evening as it can make you feel sleepy.
  • It may take 4 to 6 weeks to experience the full benefits of the medication.
  • Don't drive or do anything requiring concentration until you know how it affects you.
  • It may cause increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy and exercise regularly.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Patient Concerns

arrow
Mujhe bipolar 2 depression hai
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar disorder type 2 is like BAD type 1, except there are majorly Depressive episodes interspersed with hypomanic episodes. Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
Bipolar mood anxiety depression and jolts in body
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
arrow
Do you have any questions related to Kolzep Forte Tablet ?

User Feedback


Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Medscape. Fluoxetine+Olanzapine. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Fluoxetine+Olanzapine. [Accessed 23 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

152, I.d.c., Inudstrial Area, Rohtak - 124001, Rohtak
Best Price
₹65.45
MRP77  Get 15% OFF
Valid only on the orders above ₹500
10 tablets in 1 strip
SOLD OUT

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.