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Irbepex-H Tablet is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 09 Mar 2026 | 05:38 PM (IST)
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General Information

Contains

Irbesartan (150mg)+ Hydrochlorothiazide (12.5mg)

Marketer

Shilpex Pharmysis

Storage

Store below 25°C
The content is shown in English
Irbepex-H Tablet image
Irbepex-H Tablet image
Irbepex-H Tablet image

Product introduction

You can take Irbepex-H Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.

The most common side effect is dizziness. Other side effects include nausea, feeling tired, diarrhea, upset stomach, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of hydrochlorothiazide and helps control your blood pressure. You may experience other possible side effects, but most are rare. Hydrochlorothiazide may occasionally lead to an increase in pressure in your eye and lead to permanent eye damage if not treated. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.

This medicine is not recommended during pregnancy or while breastfeeding and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.

Uses of Irbepex-H Tablet

Benefits of Irbepex-H Tablet

Hypertension (high blood pressure)
Irbepex-H Tablet is a combination of two medicines namely Irbesartan and Hydrochlorothiazide. It is generally used when one medicine alone is not controlling your blood pressure effectively. Irbesartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Hydrochlorothiazide is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Side effects of Irbepex-H Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Irbepex-H
  • Nausea
  • Taste change
  • Upset stomach
  • Diarrhea
  • Weakness
  • Dizziness
  • Headache
  • Glucose intolerance
  • Increased blood uric acid
  • Increased blood lipid level
  • Electrolyte imbalance
  • Decreased blood pressure

How to use Irbepex-H Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Irbepex-H Tablet may be taken with or without food.

How Irbepex-H Tablet works

Irbepex-H Tablet is a combination of two medicines:

Quick tips

  • You have been prescribed Irbepex-H Tablet for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Irbepex-H Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position. 
  • Use of Irbepex-H Tablet during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Irbepex-H Tablet.
Pregnancy

Pregnancy

UNSAFE
Irbepex-H Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Irbepex-H Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Irbepex-H Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Irbepex-H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Irbepex-H Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Irbepex-H Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

Irbepex-H Tablet is a combination of two medicines that helps keep the blood pressure under control. The medicine works by reducing the risk of strokes and myocardial infarction (heart attack), thereby treating hypertension (high blood pressure).
You should take Irbepex-H Tablet exactly as directed by your doctor. It is for oral use and is usually taken once a day. You should take it with plenty of water, with or without food. It is recommended that you take this medicine at the same time every day.
If you have missed a dose of Irbepex-H Tablet, take it as soon as you remember it. However, if it is almost time for your next dose, take it in the regular schedule instead of taking the missed dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Irbepex-H Tablet may take about 2 weeks to show a visible reduction in blood pressure. Full benefits of Irbepex-H Tablet may take a little longer, about 4 weeks. However, if you are worried or have any concerns, contact your doctor.
It is important for you to know that this medicine can cause harm or death to your unborn baby. Therefore, if you are planning a pregnancy or have become pregnant, consult your doctor right away. Your doctor may switch you to a different medicine to treat your high blood pressure.
Both Irbepex-H Tablet and Telmisartan are blood pressure-lowering medicines. Irbepex-H Tablet is a relatively new medicine. It has been found to be as effective as Telmisartan in lowering blood pressure. It can be safely used in patients as it has fewer side effects.
No, do not stop taking Irbepex-H Tablet without speaking to your doctor, even if you are feeling well or your blood pressure is controlled. Stopping it suddenly may increase your blood pressure which may increase your risk of stroke.
Taking more than the recommended dose of Irbepex-H Tablet may decrease your blood pressure due to which you may feel dizzy or may even faint. Consult your doctor immediately or seek emergency medical aid in a nearby hospital.
Lifestyle changes play a major role in keeping you healthy if you are taking Irbepex-H Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Irbepex-H Tablet and to keep yourself healthy.

Fact Box

Habit Forming

No

Therapeutic Class

CARDIAC

Related lab tests

Kidney Function Test

References

  1. Hydrochlorothiazide + Irbesartan. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 17 Nov. 2017]. [Accessed 11 Apr. 2019] (online) Available from:
  2. Irbesartan+hydrochlorothiazide. Birżebbuġa, Malta: APL Swift Services (Malta) Limited; 2017. [Accessed 11 Apr. 2019] (online) Avaailable from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)Bajaj Formulations
Address: A)Khasra No. 161, Village- Lakeshwary Bhagwanpur, Roorkee Distt. Haridwar (U.K)

Marketer details

Name: Shilpex Pharmysis
Address: A-1, Ground Floor, Functional Industrial Estate, Patparganj, New Delhi - 110092

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Irbepex-H Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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