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PGDHHM, BDS
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MBA, MBBS
Last updated
06 Mar 2024 | 04:47 PM (IST)

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Insuman Comb 25 Injection

Prescription Required
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
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Product introduction

Insuman Comb 25 Injection is a combination of two medicines, an intermediate-acting and a short-acting type of insulin. It is used in the treatment of diabetes mellitus (type 1 and 2) to improve blood sugar control both in adults and children. It helps maintain the blood sugar levels in diabetic patients.

Insuman Comb 25 Injection is normally prescribed along with other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Don’t stop taking it unless your doctor tells you to.


It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.


The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it's important to always inject the correct dose of medicine only, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Some people gain weight while taking insulin.  You may also notice a rash, edema (swelling), or itching while taking this medicine.


Do not use this medicine when you have low blood glucose levels (hypoglycemia). Tell your doctor if you’ve ever had kidney, liver or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.


Uses of Insuman Comb Injection

Benefits of Insuman Comb Injection

In Treatment of Diabetes

Insuman Comb 25 Injection contains an intermediate-acting and a short-acting type of insulin. Together, they ensure rapid and consistent sugar control that helps control blood sugar levels for an entire day. It is given as an injection and your doctor or nurse will train you on the correct way to inject it. Managing blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Insuman Comb Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Insuman Comb

  • Hypoglycemia (low blood glucose level)
  • Injection site reactions (pain, swelling, redness)
  • Weight gain

How to use Insuman Comb Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Insuman Comb Injection works

Insulin Isophane has a prolonged duration of action, while human insulin has a fast onset of action. Together, they ensure rapid and consistent sugar control by facilitating reuptake of sugar in muscle and fat cells and suppressing the production of sugar in the liver.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Insuman Comb 25 Injection.
Pregnancy
SAFE IF PRESCRIBED
Insuman Comb 25 Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Insuman Comb 25 Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Insuman Comb 25 Injection should be used with caution in patients with kidney disease. Dose adjustment of Insuman Comb 25 Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver
CAUTION
Insuman Comb 25 Injection should be used with caution in patients with liver disease. Dose adjustment of Insuman Comb 25 Injection may be needed. Please consult your doctor.
Regular monitoring of glucose levels is recommended for dose adjustment.

What if you forget to take Insuman Comb Injection?

If you have missed a dose of Insuman Comb 25 Injection, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Take it 15 minutes before a meal or within 20 minutes after starting a meal.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites such as skin of the upper arms, thighs, or buttocks. After injection, the site of injection should not be massaged.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Change to another type or brand of insulin should be done under strict medical supervision as it may require a change in dosage.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Do not share your insulin device with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.
  • Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator  (2°C–8°C).

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

Patient concerns

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equivalent to Insuman 25/75 40UI medicine. Please suggest
Dr. Sfurti Mann
Internal Medicine
Insulin can't be replaced by oral medication
Sugar level above 200 after meal medicine taking glycomet gp2 BD and insulin insuman comb 25 (20 units) BD Also 3 months sugar level is 9.2
Dr. Sanjay Bhatt
Physician
Confirm about your diet failure. You needs some dose adjustment in the medicine you are taking if you are not having any diet failure. So discuss with your doctor and try to keep sugar level in normal limits.
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User feedback


FAQs

Q. Can I drink alcohol while taking Insuman Comb 25 Injection?

No, it is not safe to drink alcohol while using Insuman Comb 25 Injection. Drinking alcohol while using this medicine may lower your blood sugar levels and cause unexpected hypoglycemia.

Q. What are the instructions for storage and disposal of Insuman Comb 25 Injection?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Which is the best area to inject Insuman Comb 25 Injection?

Insuman Comb 25 Injection is to be injected under the skin (subcutaneously). The best areas to give Insuman Comb 25 Injection are your stomach, upper thigh, upper arm or buttocks.

Q. What are the symptoms of high blood sugar?

Symptoms of high blood sugar include frequent urination, increased thirst, fatigue, nausea, vomiting, shortness of breath, stomach pain, fruity breath odor, dry mouth and a fast heartbeat.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. European Medicine Agency. Insulin Isophane/NPH+Human Insulin/Soluble Insulin; 2002 [revised Nov. 2013]. [Accessed 08 Apr. 2019] (online) Available from: External Link
  2. Isophane. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2014 [revised 30 Jul. 2018]. [Accessed 08 Apr. 2019] (online) Available from: External Link
  3. Human Insulin. Gatwick, West Sussex: Novo Nordisk Limited; 2002 [revised Mar. 2018]. [Accessed 08 Apr. 2019] (online) Available from: External Link
  4. Mixtard [Summary of Product Characteristics]. Bagsværd, Denmark; Novo Nordisk A/S; 2021. [Accessed 13 Oct. 2021] (online) Available from: External Link
  5. Humulin [FDA Prescribing Information]. Indianapolis, USA; Lilly USA, LLC.; 2018. [Accessed 13 Oct. 2021] (online) Available from: External Link
  6. Medscape. Insulin Isophane/NPH/ Human Insulin/Soluble Insulin. [Accessed 08 Apr. 2019] (online) Available from: External Link

Marketer details

Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
Country of origin: Germany

356
Inclusive of all taxes
MRP367  3% OFF
3.0 ml in 1 cartridge
SOLD OUT
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