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MDS (Oral Pathology & Microbiology), BDS
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02 Aug 2019 | 11:46 AM (IST)
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Humalog 100 IU/ml Solution for Injection


Overview

Introduction of Humalog Solution for Injection

Humalog 100 IU/ml Solution for Injection is a type of rapid-acting insulin used in the treatment of diabetes mellitus. It helps to control blood sugar level and prevents long-term complications. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines if prescribed by your doctor. It may cause hypoglycemia (low blood sugar level) as a side effect.

Uses of Humalog Solution for Injection

Humalog Solution for Injection side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Injection site allergic reaction
  • Skin thickening or pits at the injection site (Lipodystrophy)
  • Rash
  • Itching

How to use Humalog Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Humalog Solution for Injection works

Humalog 100 IU/ml Solution for Injection is a fast-acting insulin, starts working within 10-20 minutes after injection. It works similar to insulin produced by the body. Insulin facilitates reuptake of glucose in muscle and fat cell and also block the release of glucose from the liver.

Humalog Solution for Injection related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Humalog 100 IU/ml Solution for Injection. Taking Humalog 100 IU/ml Solution for Injection with alcohol may affect blood glucose levels in patients with diabetes.
Pregnancy
PROBABLY SAFE
Humalog 100 IU/ml Solution for Injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the fetus, however, there are limited human studies. Please consult your doctor.
Lactation
SAFE
Humalog 100 IU/ml Solution for Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Humalog 100 IU/ml Solution for Injection should be used with caution in patients with kidney disease. Dose adjustment of Humalog 100 IU/ml Solution for Injection may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised for dose adjustment.
Liver
CAUTION
Humalog 100 IU/ml Solution for Injection should be used with caution in patients with liver disease. Dose adjustment of Humalog 100 IU/ml Solution for Injection may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised for dose adjustment.

What if you miss a dose of Humalog Solution for Injection?

If you have missed a dose of Humalog 100 IU/ml Solution for Injection, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Humalog 100 IU/ml Solution for Injection
₹774/Solution for Injection
242% costlier
Humalog 100IU/ml Kwikpen
Eli Lilly and Company India Pvt Ltd
₹283.67/ml of Solution for Injection
26% costlier

Expert Advice

  • Take it 15 minutes before a meal or within 20 minutes after starting a meal.
  • Hypoglycemia (low blood sugar level) is a common side effect. Monitor your blood sugar level regularly. 
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites.
  • Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator  (2°C–8°C).
  • Do not use if the preparation is no longer clear and colorless or if it contains particles.

Interaction with Drugs

Taking Humalog with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Digeplex T
SERIOUS
Brand(s): Densol
SERIOUS
Brand(s): Zencort-M, Welone, Rigapred
SERIOUS
Brand(s): Kopram, Ecit, Escnx
SERIOUS
Brand(s): Psycool, Proparise
SERIOUS
Brand(s): Nudiglue-C
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Defmark, Zacdef, Ecodef
SERIOUS
Brand(s): Stacort
SERIOUS

Patient Concerns

Questions Related to Humalog

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Can you interpret and let me know c peptide result if that's normal. I am type 1 diabetic and I doubt this test
Dr. Ila Jain Khandelwal
Pathologist
Dear PATIENT you for sharing your reports with me. C Peptide levels are generally high in type 2 diabetes or insulin resistance while levels are generally low in type 1 diabetes. The values can also vary depending upon anti diabetic or insulin medicine if you are taking. Please consult a diabetologist for the exact interpretation.
I have type 2 diabetes. Need to know economic alternative for Jalra 50mg. Already following germe forte 2mg. Also need alternative for ivepred.
Dr. Sanjay Bhatt
Diabetes Specialist
Almost all alternatives of good company are of same priceYou need to change saltDiabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).
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User Feedback


FAQs

Q. Is it safe to use Humalog during pregnancy and breastfeeding?

Humalog does not affect pregnant women or their fetus/newborn. Insulin requirements usually fall during the first trimester and increase during the second and third trimesters. Patients with diabetes should inform their doctor if they are pregnant or are planning to conceive. Careful monitoring of glucose control, as well as general health, is essential in pregnant patients with diabetes. Patients with diabetes who are breastfeeding may require adjustments in insulin dose, diet or both.

Q. What are the serious side effects that may be caused by Humalog?

Humalog may cause low blood sugar (hypoglycemia) with dizziness or lightheadedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, hunger, anxiety, irritability, or mood changes. Use of Insulin Lispro can affect the potassium levels in your blood. It can also cause weight loss or weight gain. You may notice changes in your diet or fall ill or feel tired. It can also cause serious allergic reactions which may lead to rashes all over the body, trouble breathing, fast heartbeat, sweating and a feeling of fainting. Fluid retention and heart failure can also be seen if Humalog is taken with other antidiabetic medicines like Thiazolidinediones (TZDs).

Q. What should I do if I experience any side effects?

If you experience any side effects, please contact your doctor.

Q. Which drugs may increase the risk of hypoglycemia (low blood sugar level) when given along with Humalog?

The use of Humalog can cause hypoglycemia if co-administered with antidiabetic agents, salicylates, sulfonamide antibiotics, monoamine oxidase inhibitors. Using Humalog with fluoxetine, pramlintide, disopyramide, fibrates, propoxyphene, pentoxifylline can increase the threat of hypoglycemia. Use of ACE inhibitors, angiotensin II receptor blocking agents, and somatostatin analogs (for e.g. octreotide) with Humalog can also cause hypoglycemia. Dose adjustment and increased frequency of glucose monitoring may be required when Humalog is co-administered with these drugs.

Q. Does Humalog need to be refrigerated?

Unopened cartridges and unused pre-filled pens of Humalog must be stored in a refrigerator where the temperature is between 2°C to 8°C. When the cartridge has been inserted into the injection pen, it should not be refrigerated and should be kept at room temperature.

Q. What should I do if the dose knob is hard to push?

Pushing the dose knob more slowly will make it easier to inject. It could also be possible that your needle is blocked. Put on a new needle and prime the pen.

Q. How do I inject the dose of my insulin?

Wash your hands before injecting. Choose a site for injection and clean the skin as instructed. Remove outer needle cap. Stabilize the skin by spreading it or pinching up a large area. Insert the needle as instructed. Press the knob. Pull the needle out and apply gentle pressure over the injection site for several seconds. Do not rub the area. Using the outer needle cap, unscrew the needle and dispose of safely. Injection sites should be rotated so that the same site is not used more than once in a month.

Q. Can Humalog be mixed with other insulin preparations?

Humalog solution must not be mixed with any other insulin preparation. Also, do not mix insulin in vials with insulin in cartridges.

Q. Where do I inject Humalog?

Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs, or upper arms. Never inject Humalog into a muscle or vein.

Q. Is it necessary to prime my pen before using it?

Yes, you need to prime your pen. Priming means removing the air from needle and cartridge that may have collected. If you do not prime, you may get too much or too little insulin. You need to turn the dose knob to 2 units. Hold your pen with the needle pointing up. Tap the cartridge holder gently to collect air bubbles at the top. Continue holding your pen with the needle pointing up. Push the dose knob in until it stops and "0" is seen in the dose window. Hold the dose knob in and count to 5 slowly. You should see insulin at the tip of the needle.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1250-51.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 733.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 722-23.
  4. Insulin lispro. Indianapolis, Indiana: Eli Lilly and Company; 2003. [Accessed 12 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, HARYANA, INDIA
A licensed pharmacy from your nearest location will deliver Humalog 100IU/ml Solution for Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹542.4
MRP678  Get 20% OFF
3 ml in 1 cartridge
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