Hituber 2V Tablet

Isoniazid (300mg)+ Vitamin B6 (Pyridoxine) (10mg)+ Rifampicin (600mg)

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Product Summary :

Hituber 2V Tablet contains isoniazid and rifampicin, which act against tuberculosis bacteria, along with pyridoxine (vitamin B6), which helps reduce the risk of nerve damage caused by isoniazid. It must be taken only as part of a doctor-prescribed TB treatment or preventive regimen. Take it regularly as directed and do not miss doses or stop treatment on your own. It may cause nausea, vomiting or orange-red urine.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 10 Nov 2026 | 01:28 PM (IST)

₹175 MRP ₹190.318% off

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General Information

Contains

Isoniazid (300mg)+ Vitamin B6 (Pyridoxine) (10mg)+ Rifampicin (600mg)

Marketer

HiGlance Laboratories

Storage

Store below 30°C

The content is shown in English

Product introduction

Hituber 2V Tablet contains two medicines that act against tuberculosis (TB) bacteria and vitamin B6 (pyridoxine), which helps reduce the risk of nerve damage associated with isoniazid.

Take this medicine exactly as prescribed by your doctor or TB treatment team. It is generally taken on an empty stomach, at least 1 hour before or 2 hours after food, unless your doctor gives different instructions. Take it regularly and complete the prescribed treatment regimen. Do not skip doses or stop treatment on your own.

Nausea, vomiting and stomach discomfort may occur. Rifampicin can also turn urine, sweat, saliva and tears orange-red; this is usually harmless. However, dark brown urine, yellowing of the skin or eyes, persistent vomiting, loss of appetite or unusual tiredness may indicate liver problems and require urgent medical assessment. Tingling or numbness in the hands and feet should also be reported.

Tell your doctor if you have liver or kidney disease, diabetes, alcohol dependence, HIV infection or a history of nerve problems. Inform your doctor about all medicines you take, as rifampicin interacts with many medicines, including hormonal contraceptives and blood thinners. Avoid alcohol during treatment. Consult your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Hituber Tablet

Treatment of Tuberculosis (TB)

Benefits of Hituber Tablet

Treatment of Tuberculosis (TB)
Hituber 2V Tablet contains two medicines that act against the bacteria responsible for tuberculosis. Isoniazid and rifampicin help kill or stop the growth of TB bacteria, while pyridoxine helps protect against nerve-related side effects of isoniazid. Use this combination only as part of the complete treatment regimen prescribed by your doctor.

Side effects of Hituber Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Hituber

Nausea
Vomiting
Rash
Fever
Dark colored urine
Sweating
Increased sputum production
Salivation
Watery eyes
Peripheral neuropathy (tingling and numbness of feet and hand)
Increased liver enzymes
Jaundice

How to use Hituber Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hituber 2V Tablet is to be taken on an empty stomach.
Avoid Hituber 2V Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Hituber Tablet works

Hituber 2V Tablet combines two anti-tuberculosis medicines with vitamin B6 (pyridoxine). Isoniazid prevents TB bacteria from producing mycolic acids, which are essential components of their protective cell wall. Rifampicin blocks bacterial DNA-dependent RNA polymerase, an enzyme needed to produce RNA and make essential proteins. Together, these medicines act against TB bacteria. Pyridoxine helps prevent nerve damage, such as tingling and numbness in the hands and feet, which may occur during isoniazid treatment.

Dosage

Take Hituber 2V Tablet exactly as prescribed by your doctor or TB treatment team. The dose depends on your body weight, treatment regimen and the strength of the tablet. It is generally taken on an empty stomach with water, at least 1 hour before or 2 hours after food. Follow the instructions given by your treatment team if they differ. Do not change the dose, skip doses or stop treatment on your own.

Quick tips

Hituber 2V Tablet should be taken on an empty stomach but at the same time every day.
Do not skip any doses and finish the full course of treatment even if you feel better.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how the medicine affects you.
Avoid taking hormone-based birth control methods as Hituber 2V Tablet may decrease their effectiveness.
Avoid consuming alcohol while taking this medication as it can enhance the dizziness.
Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.

Safety advice

Alcohol

UNSAFE

Consumption of alcohol with Hituber 2V Tablet may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Hituber 2V Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

UNSAFE

Hituber 2V Tablet may cause side effects that could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Hituber 2V Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

SAFE IF PRESCRIBED

Hituber 2V Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

What is Hituber 2V Tablet used for?

Hituber 2V Tablet contains two medicines that act against TB bacteria, along with pyridoxine (vitamin B6), which helps reduce the risk of nerve damage associated with isoniazid. It should be used only as part of the TB treatment or preventive regimen prescribed by your doctor.

Is Hituber 2V Tablet enough to cure active tuberculosis?

Not necessarily. Active TB usually requires a combination of multiple anti-TB medicines, selected according to the type of TB and drug-susceptibility results. This product contains only isoniazid and rifampicin as anti-TB agents. Do not use it as the only treatment for active TB unless your doctor has specifically prescribed it as part of an appropriate regimen.

Why should I take Hituber 2V Tablet on an empty stomach?

Food can reduce the absorption of Hituber 2V Tablet which may affect how much medicine enters your bloodstream. It is generally recommended to take the medicine on an empty stomach, at least 1 hour before or 2 hours after food. Follow the instructions on your specific product and from your doctor.

Why has my urine turned orange or red after taking Hituber 2V Tablet?

Hituber 2V Tablet can cause orange-red discolouration of urine and other body fluids, including sweat, saliva and tears. This is an expected and usually harmless effect that generally disappears after treatment ends. However, dark brown urine, particularly with yellowing of the skin or eyes, nausea or loss of appetite, may indicate liver injury and requires urgent medical assessment.

Can Hituber 2V Tablet affect my birth control pills?

Yes. Hituber 2V Tablet can reduce the effectiveness of hormonal contraceptives, including birth control pills, patches, implants and some other hormonal methods. Discuss a reliable alternative or additional non-hormonal contraceptive method with your doctor before starting treatment. Do not rely on your usual hormonal contraceptive method without discussing this interaction.

Can I take other medicines with Hituber 2V Tablet?

Tell your doctor about all medicines, supplements and herbal products you use. Hituber 2V Tablet can interact with many medicines, including blood thinners, medicines for diabetes, HIV medicines, anti-seizure medicines and hormonal contraceptives. Your doctor may need to adjust treatment or monitor you more closely.

What symptoms should I watch for while taking Hituber 2V Tablet?

Watch for loss of appetite, persistent nausea or vomiting, unusual tiredness, abdominal pain, dark brown urine or yellowing of the skin or eyes. These may be signs of liver injury. Seek urgent medical advice if they occur. Do not wait for your next routine appointment.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: HiGlance Laboratories
Address: 1204, 12th Floor, Hemkunt Chambers-89, Nehru Place, New Delhi-110 019

Vendor Details

Country of origin: India

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Hituber 2V Tablet

Hituber 2V Tablet

Product Summary :

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Hituber Tablet

Benefits of Hituber Tablet

Side effects of Hituber Tablet

How to use Hituber Tablet

How Hituber Tablet works

Dosage

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Hituber 2V Tablet used for?

Is Hituber 2V Tablet enough to cure active tuberculosis?

Why should I take Hituber 2V Tablet on an empty stomach?

Why has my urine turned orange or red after taking Hituber 2V Tablet?

Can Hituber 2V Tablet affect my birth control pills?

Can I take other medicines with Hituber 2V Tablet?

What symptoms should I watch for while taking Hituber 2V Tablet?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests