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HI Five D Tablet is a prescription medicine. It treats gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease. It also manages nausea, vomiting, and indigestion. It reduces excess stomach acid production and prevents the reflux of stomach acid into the food pipe.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 24 Sep 2025 | 02:26 PM (IST)
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HI Five D Tablet image
HI Five D Tablet image

Product introduction

HI Five D Tablet is a combination of two medicines. It is to be taken in the dose and duration advised by your doctor. In case you have missed a dose, take it as soon as you remember. Finish the full course of treatment even if you feel better. A high dose or overdose may have harmful effects on the body.

This medicine is generally well tolerated by patients. Some of the common side effects of this medicine are stomach pain, diarrhea, constipation, and headache. Before taking the medicine always consult your doctor if you are pregnant, breastfeeding. Let your doctor also know if you are suffering from any severe stomach, liver, kidney disease, or any known disease.

Uses of HI Five D Tablet

Benefits of HI Five D Tablet

Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. HI Five D Tablet reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Treatment of Peptic ulcer disease
Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). HI Five D Tablet reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.

Side effects of HI Five D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of HI Five D
  • Stomach pain
  • Diarrhea
  • Constipation
  • Headache
  • Flatulence
  • Dryness in mouth
  • Dizziness
  • Fatigue

How to use HI Five D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. HI Five D Tablet is to be taken empty stomach.

How HI Five D Tablet works

HI Five D Tablet is a combination of two medicines: Domperidone and Ilaprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Ilaprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Quick tips

  • You have been prescribed HI Five D Tablet for the treatment of acidity and heartburn.
  • Take it one hour before the meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with HI Five D Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
HI Five D Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CAUTION
HI Five D Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving

Driving

UNSAFE
HI Five D Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
HI Five D Tablet should be used with caution in patients with kidney disease. Dose adjustment of HI Five D Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
HI Five D Tablet should be used with caution in patients with liver disease. Dose adjustment of HI Five D Tablet may be needed. Please consult your doctor.
Use of HI Five D Tablet is not recommended in patients with moderate and severe liver disease.

Frequently asked questions

HI Five D Tablet is used to treat gastroesophageal reflux disease (acid reflux), peptic ulcer disease, nausea, vomiting, and indigestion. It reduces excess stomach acid production and prevents the reflux of stomach acid into the food pipe.
People should avoid taking HI Five D Tablet if they are allergic to any ingredient in it, have severe liver or kidney disorders, gastrointestinal obstruction, cardiac arrhythmias (like prolonged QT), or are pregnant without a doctor's advice.
Although they are rare, serious side effects of HI Five D Tablet include irregular heartbeat, cardiac issues, severe allergic reactions, and liver problems. Immediate medical attention is required if these occur.
Long-term HI Five D Tablet use should be monitored by a doctor to reduce risks of side effects and assess ongoing need.
While on HI Five D Tablet treatment, if you experience chest pain, vision changes, persistent vomiting, severe diarrhea, allergic reactions, or worsening symptoms, contact your doctor immediately.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Akumentis Healthcare Ltd
Address: 204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver HI Five D Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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