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Hepgel 250IU Ointment

Heparin (250IU)
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Hepgel 250IU Ointment is an anticoagulant that prevents the clotting of blood. It is applied on the skin for the treatment of post-injection superficial thrombophlebitis (inflammation of a vein due to a blood clot). It speeds up the formation of blood clots and decreases pain and pain and swelling.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Mar 2026 | 01:49 AM (IST)
MRP ₹47.38
 
 
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General Information

The content is shown in English
Hepgel 250IU Ointment image
Hepgel 250IU Ointment image

Product introduction

Hepgel 250IU Ointment may also be used for treating extensive superficial bruises. It should be used as advised by your doctor. This medicine is meant for external use only. It should be applied only to the affected area of the skin as per the dosage and schedule prescribed by your doctor. In order to get the most benefit, apply it regularly and preferably at the same time each day. Do not use larger amounts or apply it more often or for a longer duration than directed. This will only increase the risk of side effects.

Avoid any contact with your eyes, nose, or mouth. Rinse it off with water if you accidentally get the medicine in these areas. Local side effects like rashes may be seen after application. This is usually temporary and resolves quickly. Consult your doctor if it bothers you or if your condition doesn't improve.

Uses of Hepgel Ointment

  • Prevention of Blood clots

Benefits of Hepgel Ointment

Prevention of Blood clots
Formation of blood clots blocks one or more veins, usually in your legs. Hepgel 250IU Ointment is used to prevent formation of blood clots near the surface of your skin. It dissolves the clots and also relieves pain and inflammation by increasing the blood flow. This improves the overall healing process.
Use it as advised by the doctor to get maximum benefit. The condition usually improves on its own in sometime. However, your doctor might recommend applying heat to the painful area, elevating the affected leg, using an over-the-counter painkiller and possibly wearing compression stockings.

Side effects of Hepgel Ointment

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Hepgel
  • Skin rash

How to use Hepgel Ointment

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.

How Hepgel Ointment works

Hepgel 250IU Ointment is an anticoagulant. It penetrates into the diseased tissue immediately upon application without leaving residues or degreasing the skin. This helps in strengthening and supporting the connective tissues, thus alleviating pain and speeding up healing.

Quick tips

  • Apply it precisely on the affected area as instructed by your doctor.
  • Wash your hands properly with soap before and after applying the gel.
  • It is given as an injection or drip into the veins by a healthcare professional.
  • It makes your skin more sensitive toward sunlight. Apply sunscreen or wear protective clothing while going out.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Hepgel 250IU Ointment during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Hepgel 250IU Ointment may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Hepgel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Mild

Argatroban (Injection Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).

Frequently asked questions

Hepgel 250IU Ointment is used for the prevention of a blood clot that causes inflammation or swelling of a vein. When applied to the affected area, Hepgel 250IU Ointment penetrates the skin to help reduce inflammation and pain, and aid faster healing.
Hepgel 250IU Ointment is usually used for a short term and can be discontinued when the symptoms are relieved. However, Hepgel 250IU Ointment should be continued if the doctor has advised to do so.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
It is important to know that Hepgel 250IU Ointment is for external use only. Do not apply close to the eyes, mouth, nose, or any cut, broken, or burned skin. In some patients, use of this medicine causes an increase in sensitivity to UV rays. It is recommended to avoid the exposure to direct sunlight as much as possible. If it is unavoidable to expose yourself to sunlight then wear as much protective clothing as possible and use sunscreen.
Hepgel 250IU Ointment is effective if used in the dose and duration advised by your doctor. Do not stop using it even if you see improvement in your condition. If you stop using Hepgel 250IU Ointment too early, the symptoms may return or worsen.
Yes, Hepgel 250IU Ointment increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Hepgel 250IU Ointment can interact with several medicines. Talk to your doctor, and inform him about using Hepgel 250IU Ointment before taking any prescription or non prescription medicine.
Hepgel 250IU Ointment reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Hepgel 250IU Ointment. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Fact Box

Chemical Class

Glycosaminoglycans

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

Unfractionated Heparin (UFH)

References

  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 853-59.
  2. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 591-93.
  3. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 367-73.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 652-53.
  5. Central Drugs Standard Control Organisation (CDSCO). Heparin. [Accessed 18 Mar. 2019] (online) Available from:
  6. Heparin sodium. Florence, Italy: A. Menarini Industrie Farmaceutiche Riunite S.r.l.; [Accessed 05 Jan. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gland Pharma Limited
Address: Gland Pharma Limited, 6-3-865/1/2, Greenland Apartments, Ameerpet, Hyderabad - 500016, India

Vendor Details

Country of origin: India
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