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18 Feb 2020 | 05:25 PM (IST)
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Gynarone 400mg Capsule


Overview

Introduction

Gynarone 400mg Capsule is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance.

It is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).  It should be taken without food, preferably in the evening or at bedtime. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well. 

The most common side effects include headache, feeling very tired, stomach cramps, pain or swelling in your abdomen and feeling sick. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently. If you experience dizziness or tiredness, avoid driving or activity which requires mental concentration. 

Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina or liver disease. You will probably have several tests both before and during treatment to check your womb.  Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. In general, it is advisable to avoid alcohol and smoking.

Side effects of Gynarone Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gynarone

  • Headache
  • Vomiting
  • Bloating
  • Nausea
  • Stomach pain
  • Uterine bleeding

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Bloating
    Try eating small and frequent meals. Drink and chew your food slowly. Exercise regularly to improve how your body digests food. Try not to swallow too much air. This can happen when you talk and eat at the same time. Avoid drinking with a straw, chewing gum and smoking as these can also make you swallow air. Try to limit foods that are hard to digest or produce gas (such as fried and fatty foods, cheese, beans, cabbage, onion, whole grains and many others). Avoid drinking alcohol, carbonated soft drinks and fruit juices. If you wear dentures, make sure they fit properly. Some over-the-counter medicines can help. Talk to your doctor about possible medication if your condition does not improve.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Stomach pain
    Try to get plenty of rest and relax. Putting a heat pad or covered hot water bottle on your stomach may relieve the stomach pain. It may help if you eat and drink slowly and have smaller and more frequent meals. Reduce your intake of coffee, tea and alcohol as these can make the pain worse. If you are in a lot of pain, speak to your doctor about possible medication. Your doctor may be able to prescribe some over-the-counter medicines to help reduce the pain.

How to use Gynarone Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Gynarone 400mg Capsule is to be taken empty stomach.

How Gynarone Capsule works

Gynarone 400mg Capsule is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of oestrogen when used for the treatment of postmenopausal symptoms.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Gynarone 400mg Capsule. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Gynarone 400mg Capsule is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breastfeeding
SAFE IF PRESCRIBED
Gynarone 400mg Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Gynarone 400mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Gynarone 400mg Capsule in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Gynarone 400mg Capsule in patients with liver disease. Please consult your doctor.
Use of Gynarone 400mg Capsule is however not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Gynarone 400mg Capsule
₹37.5/Capsule
Holderon 400mg Capsule
Ultra Biotech Formulations
₹40/Capsule
7% costlier

Quick Tips

  • Gynarone 400mg Capsule is used in the treatment of female infertility and as a part of hormone replacement therapy.
  • It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
  • It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
  • It should be taken without food, preferably in the evening or at bedtime.
  • It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how Gynarone 400mg Capsule affects you.
  • It may cause bleeding  or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Patient Concerns

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I have been told by doctors I have cystitis also simple cyst in right ovary . What should I be doing its been two years I have this issue
Dr. Megha Tuli
Obstetrics and Gynaecology
Hi PATIENT hormone therapy helps with cysts. Ask your doctor for a hormone replacement.
I am a male to female transsexual and I need Bilateral Orchiectomy at a fair cost I am already on hormone replacement therapy for 2 years anti androgen/spirnolactone (Aldactone) and estrodiol valerate progynova, I need to have bilateral orchiectomy at the cheapest option
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to your nearest doctor
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Do you have any questions related to Gynarone 400mg Capsule ?

User Feedback


FAQs

Q. Can you take Gynarone every day?

Yes, Gynarone can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.

Q. Does Gynarone cause weight gain?

Yes, taking Gynarone may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Gynarone is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

Q. How is progesterone beneficial for fertility and pregnancy?

Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Gynarone (form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.

Related Products

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
  2. Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
  3. Mayo Clinic. Progesterone. [Accessed 03 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
A licensed vendor partner from your nearest location will deliver Gynarone 400mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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